We narrowed to 145 results for: lias

1. Inzolia library in pRDA_550

   Pooled Library

   #209552

   Purpose

   The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

   Depositor

   John Doench

   Article

   Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

2. Inzolia library in pRDA_052

   Pooled Library

   #209551

   Purpose

   The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

   Depositor

   John Doench

   Article

   Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

   Pooled Library

   #161769

   Purpose

   Inducible CRISPRi library

   Depositor

   Nicholas Ingolia

   Article

   McGlincy et al BMC Genomics. 2021 Mar 23;22(1):205. doi

   Expression

   Yeast

   Species

   Saccharomyces cerevisiae

   Use

   CRISPR

   Available since

   Nov. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

4. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

5. Human Epigenetic Knockout Library

   Pooled Library

   #162256

   Purpose

   Lentiviral CRISPR library targets human epigenetic genes

   Depositor

   Kivanc Birsoy

   Article

   Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

6. TRE-MPRA_minCMV Library

   Pooled Library

   #201012

   Purpose

   Massively parallel reporter assay (MPRA) library with minCMV promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

7. TRE-MPRA_minPromega Library

   Pooled Library

   #201013

   Purpose

   Massively parallel reporter assay (MPRA) library with minPromega promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

8. TRE-MPRA_minTK Library

   Pooled Library

   #201014

   Purpose

   Massively parallel reporter assay (MPRA) library with minTK promoter

   Depositor

   Justin English

   Article

   Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

   Expression

   Mammalian

   Use

   Luciferase

   Available since

   Oct. 31, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Human sgRNA library Gattinara in pRDA_118 backbone

   Pooled Library

   #136986

   Purpose

   Expresses sgRNAs targeting human genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Mouse sgRNA library Gouda in pRDA_118 backbone

    Pooled Library

    #136987

    Purpose

    Expresses sgRNAs targeting mouse genes

    Depositor

    John Doench

    Article

    DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

11. SPLINTR mCHERRY v1

    Pooled Library

    #179775

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

12. SPLINTR BFP v1

    Pooled Library

    #179776

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

13. Human SLC SAM Library

    Pooled Library

    #132561

    Purpose

    Expresses gRNAs for activation of human Solute Carrier family genes

    Depositor

    Giulio Superti-Furga

    Article

    Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 18, 2020

    Availability

    Academic Institutions and Nonprofits only

14. SPLINTR GFP v1

    Pooled Library

    #179774

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

15. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

    Pooled Library

    #89640

    Purpose

    Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

    Depositor

    Wensheng Wei

    Article

    Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 17, 2017

    Availability

    Academic Institutions and Nonprofits only

16. pMuSIC pool v1.0

    Pooled Library

    #227193

    Purpose

    Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

    Depositor

    Marc Birtwistle

    Article

    Lu et al bioRxiv [Preprint]. 2024 Oct 24:2024.10.

    Expression

    Mammalian

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

17. pUC57kan-T7-mt-gRNA library

    Pooled Library

    #82480

    Purpose

    Pool of sgRNAs to remove mouse mitochondrial DNA reads in the sequencing of genomic libraries

    Depositor

    Wei Xie

    Article

    Wu et al Nature. 2016 Jun 30;534(7609):652-7.

    Available since

    April 5, 2017

    Availability

    Academic Institutions and Nonprofits only

18. Human Transporter Knockout library

    Pooled Library

    #213695

    Purpose

    Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

19. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

    Pooled Library

    #171531

    Purpose

    Pooled gRNA library against human ubiquitination and de-ubiquitination complex genes (UBDUB)

    Depositor

    Chunliang Li

    Article

    Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

    Pooled Library

    #138015

    Purpose

    This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

    Depositor

    William Pu

    Article

    VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

    Species

    Mus musculus

    Use

    AAV, CRISPR, and Cre/Lox

    Available since

    April 17, 2020

    Availability

    Academic Institutions and Nonprofits only