We narrowed to 32,277 results for: uros

1. EIF2AK2 gRNA (BRDN0001146342)

   Plasmid

   #75637

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EIF2AK2

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EIF2AK2 (EIF2AK2 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. FUW-hSNCA-GFP

   Plasmid

   #215489

   Purpose

   Lentiviral expression and easy visualization of alpha-synuclein in mammalian cells

   Depositor

   Ophir Shalem

   Article

   Santhosh Kumar et al Sci Adv. 2024 Feb 9;10(6):eadj4767. doi:

   Insert

   alpha-synuclein (SNCA Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Expression

   Mammalian

   Promoter

   Ubc

   Available Since

   April 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV2ss-U6-sgHTT1-7sk-sgCas9

   Plasmid

   #190900

   Purpose

   AAV-KamiCas9 vector expressing sgGFP and human HTT sgRNAs

   Depositor

   Nicole Déglon

   Article

   Duarte et al Mol Ther Methods Clin Dev. 2023 Mar 27;2

   Insert

   sgRNA (HTT Human, spCas9)
   

   Use

   AAV and CRISPR

   Promoter

   U6 and 7sk

   Available Since

   March 27, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pcDNA5-FRT/T0-Flag-RECQL5

   Plasmid

   #222620

   Purpose

   Mammalian expression vector of flag-tagged RECQL5

   Depositor

   Daniel Durocher

   Article

   Zhao et al Mol Cell. 2023 Aug 3;83(15):2792-2809.e9

   Insert

   RECQL5 (RECQL5 Human)
   

   Tags

   Flag

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   July 25, 2024

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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5. pSN840

   Plasmid

   #184832

   Purpose

   Expresses human KIF5A(∆exon27) and human KLC1 in insect cells

   Depositor

   Kyoko Chiba

   Article

   Nakano et al Genes Cells. 2022 Apr 17. doi: 10.1111/g

   Inserts

   KIF5A (∆exon27) (KIF5A Human)
   KLC1 (KLC1 Human)
   

   Use

   Cre/Lox

   Tags

   His-FLAG and mScarlet-2xStrepII

   Expression

   Insect

   Mutation

   ∆exon27 form of human KIF5A

   Promoter

   p10 and polyhedrin

   Available Since

   July 19, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAG303-Gal-PA50

   Plasmid

   #84906

   Purpose

   induce expression of dipeptide repeat PA in yeast

   Depositor

   Aaron Gitler

   Article

   Jovicic et al Nat Neurosci. 2015 Sep;18(9):1226-9. doi

   Insert

   PA50 (C9orf72 Synthetic)
   

   Tags

   FLAG and Myc

   Expression

   Yeast

   Promoter

   GAL1

   Available Since

   April 13, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-CAG-mCherry-Tandem-PSAM4-GlyR

   Plasmid

   #208361

   Purpose

   Expression of the inhibitory chemogenetic tool PSAM4-GlyR and mCherry reporter. Application of ultrapotent agonists induces neuronal silencing.

   Depositor

   David Bennett

   Article

   Perez-Sanchez et al Sci Transl Med. 2023 Oct 4;15(716):eadh3

   Insert

   mCherry-TANDEM-PSAM4-GlyR
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Oct. 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pDEST53-LRRK2-3XKD

   Plasmid

   #25049

   Depositor

   Mark Cookson

   Article

   Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

   Insert

   LRRK2 (LRRK2 Human)
   

   Tags

   GFP

   Expression

   Mammalian

   Mutation

   "Kinase Dead" Lysine 1906 mutated to A…

   Available Since

   June 17, 2010

   Availability

   Academic Institutions and Nonprofits only

9. Slc17a7-IRES2-Cre targeting vector

   Plasmid

   #61574

   Purpose

   Target the Cre recombinase gene to the stop codon of the mouse Slc17a7 (VGlut1) gene

   Depositor

   Hongkui Zeng

   Article

   Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

   Insert

   Slc17a7-IRES2-Cre
   

   Use

   Cre/Lox and Mouse Targeting

   Available Since

   July 30, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV hPGRN

    Plasmid

    #213682

    Purpose

    Expresses human progranulin (PGRN) with an N-terminal twin-Strep-V5 tag

    Depositor

    Thomas Kukar

    Article

    Root et al Cell Rep. 2024 Nov 19;43(12):114985. doi

    Insert

    Human Progranulin (hPGRN) (GRN Human)
    

    Use

    AAV

    Tags

    Twin-Strep tag and V5 tag (after signal peptide)

    Promoter

    cytomegalovirus enhancer/chicken β-actin promoter

    Available Since

    Dec. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAG303-Gal-GA50

    Plasmid

    #84907

    Purpose

    induce expression of dipeptide repeat GA in yeast

    Depositor

    Aaron Gitler

    Article

    Jovicic et al Nat Neurosci. 2015 Sep;18(9):1226-9. doi

    Insert

    GA50 (C9orf72 Synthetic)
    

    Tags

    FLAG and Myc

    Expression

    Yeast

    Promoter

    GAL1

    Available Since

    Dec. 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-nEF-Coff/Fon-ChRmine-oScarlet

    Plasmid

    #137160

    Purpose

    Intersectional viral expression of ChRmine-p2a-oScarlet in cells expressing Flp AND NOT Cre

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Has Service

    AAV8

    Insert

    Coff/Fon-ChRmine-p2a-oScarlet
    

    Use

    AAV, Cre/Lox, and Synthetic Biology ; Flp/frt

    Mutation

    oScarlet E95D

    Promoter

    nEF

    Available Since

    June 25, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAG303-Gal-PR50

    Plasmid

    #84905

    Purpose

    induce expression of dipeptide repeat PR in yeast

    Depositor

    Aaron Gitler

    Article

    Jovicic et al Nat Neurosci. 2015 Sep;18(9):1226-9. doi

    Insert

    PR50 (C9orf72 Synthetic)
    

    Tags

    FLAG and Myc

    Expression

    Yeast

    Promoter

    GAL1

    Available Since

    Nov. 22, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-Ef1a-Con/Foff 2.0-GCaMP6F

    Plasmid

    #137123

    Purpose

    Intersectional viral expression of GCaMP6F in cells expressing Cre AND NOT Flp

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Has Service

    AAV8

    Insert

    Con/Foff 2.0-GCaMP6F
    

    Use

    AAV, Cre/Lox, and Synthetic Biology ; Flp/frt

    Mutation

    Removed RSET tag

    Promoter

    EF1a

    Available Since

    June 25, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAV pCAG-FLEX2-tTA2-WPRE-bGHpA

    Plasmid

    #65458

    Purpose

    Can be used to generate AAV virus that will express the tetracycline transactivator tTA2 from the CAG promoter in a Cre-dependent manner

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Insert

    tTA2
    

    Use

    AAV

    Promoter

    CAG

    Available Since

    July 7, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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16. GABA(A) receptor subunit a2SE

    Plasmid

    #49169

    Purpose

    pHluorin-tagged GABA A receptor subunit (alpha 2) produces minimal fluorescence during trafficking and a robust fluorescent signal at the cell surface

    Depositor

    Tija Jacob, Stephen Moss

    Article

    Tretter et al J Neurosci. 2008 Feb 6;28(6):1356-65. do

    Insert

    GABA(A) receptor subunit alpha-2 (GABRA2 Human)
    

    Tags

    HA, bovine alpha 1 signal sequence, and pHGFP (pH…

    Expression

    Mammalian

    Mutation

    T343A

    Promoter

    CMV

    Available Since

    Dec. 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-nEF-Con/Fon-ChRmine-oScarlet

    Plasmid

    #137159

    Purpose

    Intersectional viral expression of ChRmine-p2a-oScarlet in cells expressing both Cre AND Flp

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Has Service

    AAV8

    Insert

    Con/Fon-ChRmine-p2a-oScarlet
    

    Use

    AAV, Cre/Lox, and Synthetic Biology ; Flp/frt

    Mutation

    oScarlet E95D

    Promoter

    nEF

    Available Since

    June 25, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. pOTTC293 - pAAV EF1a V5-synuclein (WT)

    Plasmid

    #60057

    Purpose

    An AAV packaging vector that expresses wildtype alpha-synuclein under control of the EF1a promoter.

    Depositor

    Brandon Harvey

    Article

    Savolainen et al Neurobiol Dis. 2014 Aug;68:1-15. doi: 10

    Insert

    alpha-synuclein (SNCA human, Human)
    

    Use

    AAV

    Tags

    V5

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    Oct. 9, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAG303-Gal-GR100

    Plasmid

    #84908

    Purpose

    induce expression of dipeptide repeat GR in yeast

    Depositor

    Aaron Gitler

    Article

    Jovicic et al Nat Neurosci. 2015 Sep;18(9):1226-9. doi

    Insert

    GR100 (C9orf72 Synthetic)
    

    Expression

    Yeast

    Promoter

    GAL1

    Available Since

    Nov. 30, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-nEF-Con/Fon-NpHR3.3-EYFP

    Plasmid

    #137152

    Purpose

    Intersectional viral expression of NpHR3.3-EYFP in cells expressing both Cre AND Flp

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Has Service

    AAV8

    Insert

    Con/Fon-NpHR3.3-EYFP
    

    Use

    AAV, Cre/Lox, and Synthetic Biology ; Flp/frt

    Mutation

    W179F

    Promoter

    nEF

    Available Since

    June 25, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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