We narrowed to 15,447 results for: grn

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pJZC73

Plasmid

#62341

Purpose

sgRNA (no RNA aptamer addition) with COM-KRAB effector for mammalian cells

Depositor

Wendell Lim, Stanley Qi

Publication

Zalatan et al Cell. 2014 Dec 18. pii: S0092-8674(14)01

Inserts

sgRNA
COM-KRAB

Use

Lentiviral

Tags

KRAB

Expression

Mammalian

Mutation

Targets sv40 promoter, sequence: GAATAGCTCAGAGGCC…

Promoter

CMV and U6

Available since

April 2, 2015

Availability

Academic Institutions and Nonprofits only

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pSUPERIOR.puro-shREV3-4

Plasmid

#38029

Depositor

Emanuela Felley-Bosco, Rolf Stahel

Publication

Knobel et al Neoplasia. 2011 Oct;13(10):961-70.

Insert

shREV3-4 (REV3L Human, human, Mouse, Rat)

Use

RNAi

Available since

Aug. 20, 2012

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
DCX 3UTRm3hp

Plasmid

#28302

Depositor

Joseph Loturco

Publication

Bai et al Nat Neurosci. 2003 Dec . 6(12):1277-83.

Insert

Doublecortin 3' Untranslated region mutated

Expression

Mammalian

Mutation

3 base pair mutation in DCX 3'UTR region

Available since

May 12, 2011

Availability

Academic Institutions and Nonprofits only
pLKO-Tet-On-AHR-shRNA1

Plasmid

#166889

Purpose

Lentivirus for inducible knockdown of human AHR

Depositor

Roland Friedel

Publication

Halawani et al Nature. 2026 May;653(8116):1119-1129. do

Insert

AHR shRNA (AHR Human)

Use

Lentiviral

Expression

Mammalian

Promoter

TRE

Available since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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LT3GEPIR-CCND1shRNA2

Plasmid

#220578

Purpose

To inducibly knockdown CCND1 expression

Depositor

Sean Lee

Publication

Magrath et al Cancer Res. 2024 May 2;84(9):1426-1442.

Insert

CCND1 shRNA2 (CCND1 Human)

Use

Lentiviral

Promoter

TRE3G (TetOP) promoter

Available since

July 1, 2024

Availability

Academic Institutions and Nonprofits only

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p207-Switch-ON (FRT)

Plasmid

#217886

Purpose

Retroviral Switch-ON vector for sgRNA expression; U6-BbsIx2-SWITCH-ON-scaffold; neoR

Depositor

Ulrich Elling

Publication

Chylinski et al Nat Commun. 2019 Nov 29;10(1):5454. doi:

Type

Empty backbone

Use

CRISPR and Retroviral

Expression

Mammalian

Promoter

hU6

Available since

May 20, 2024

Availability

Academic Institutions and Nonprofits only

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pBFC0694

Plasmid

#186693

Purpose

ShDART under control of Lac promoter, original configuration (pre-gRNA terminator and J23119 promoter), Sh_lacZ_α_1 gRNA, GmR+sfGFP cargo

Depositor

Jennifer Doudna

Publication

Rubin et al Nat Microbiol. 2022 Jan;7(1):34-47. doi:

Inserts

tnsB
tnsC
tniQ
Cas12k
Sh_lacZ_α_1 gRNA
Tn7 transposon
GmR+sfGFP ShDART Cargo

Expression

Bacterial

Promoter

PLac

Available since

Sept. 9, 2022

Availability

Academic Institutions and Nonprofits only

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pAAV-shMcu-2

Plasmid

#181867

Purpose

Expresses Mcu-targeted shRNA under control of the U6 promoter and hrGFP under control of the synthetic CAG promoter

Depositor

Hilmar Bading

Publication

Qiu et al Nat Commun. 2013;4:2034. doi: 10.1038/nc

Insert

mitochondrial calcium uniporter (Mcu Mouse)

Use

AAV, Adenoviral, and Mouse Targeting

Tags

hrGFP

Expression

Mammalian

Promoter

U6

Available since

March 17, 2022

Availability

Academic Institutions and Nonprofits only

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pAPM-D4 miR30-AGO2 ts2

Plasmid

#115854

Purpose

AGO2 knockdown

Depositor

Jeremy Luban

Publication

Yurkovetskiy et al Nat Microbiol. 2018 Dec;3(12):1354-1361.

Insert

AGO2 shRNA (AGO2 Human)

Use

Lentiviral

Promoter

SFFV

Available since

Jan. 9, 2019

Availability

Academic Institutions and Nonprofits only

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pLV(shRNA)-Puro-U6-CCEPR

Plasmid

#108277

Purpose

shRNA for CCEPR lncRNA

Depositor

Karl Munger

Publication

Sharma et al Virology. 2018 Feb 7;518:8-13. doi: 10.1

Insert

CCEPR (CCEPR Human)

Use

Lentiviral

Promoter

U6

Available since

April 3, 2018

Availability

Academic Institutions and Nonprofits only

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tet-pLKO shMKP1.v2 puro

Plasmid

#87791

Purpose

Expresses an inducible short hairpin targeting human MKP1 sequence

Depositor

Kevin Janes

Publication

Shah et al Mol Cell Proteomics. 2017 Apr;16(4 suppl

Insert

shMKP1 (DUSP1 Human)

Use

Lentiviral

Expression

Mammalian

Promoter

TRE tight

Available since

March 27, 2017

Availability

Academic Institutions and Nonprofits only

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shMEK1/2 v2 neo

Plasmid

#72570

Purpose

Hairpin targeting MEK1 and MEK2 (murine).

Depositor

Kevin Janes

Publication

Jensen et al Cell Syst. 2016 Feb 24;2(2):112-121.

Insert

MEK1/2 (Map2k1, Map2k2 Mouse)

Use

Lentiviral

Expression

Mammalian

Available since

July 12, 2016

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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NHR1+2-Flag pcDNA3.1

Plasmid

#17316

Depositor

Joan Conaway, Ronald Conaway

Publication

Koutelou et al J Biol Chem. 2008 Feb 15;283(7):3846-53.

Insert

Neuralized-like (Neurl1a Mouse)

Use

RNAi

Tags

FLAG

Expression

Mammalian

Available since

Feb. 20, 2008

Availability

Academic Institutions and Nonprofits only
PRAS40 (mouse) shRNA

Plasmid

#15672

Depositor

John Lawrence

Publication

Wang et al J Biol Chem. 2007 Jul 6. 282(27):20036-4

Insert

PRAS40 shRNA (Akt1s1 Mouse)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

Sept. 24, 2007

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
pAAV-3xsgMyo7b-CMV-5’dCas9-SDS-BD10-SV40pA

Plasmid

#216322

Purpose

Transactivation of murine Myo7b gene via split dCas9-VPR (REVeRT system).

Depositor

Elvir Becirovic

Publication

Riedmayr et al Nat Commun. 2023 Oct 18;14(1):6578. doi:

Insert

Split Cas9-VPR + splice donor site + gRNAs targeting the murine Myo7b locus for transactivation

Use

AAV

Promoter

CMV

Available since

March 25, 2024

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pD649-HAsp-FCGRT-COMP5AP-AviTag-9xHis

Plasmid

#157384

Purpose

Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

Depositor

Chris Garcia

Publication

Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

Insert

FCGRT (FCGRT Human)

Tags

COMP5AP-AviTag-9xHis

Expression

Mammalian

Promoter

CMV/SP6

Available since

March 8, 2023

Availability

Academic Institutions and Nonprofits only

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pXPR_003 sgSMARCA4 guide 2

Plasmid

#193605

Purpose

SMARCA4 knockout

Depositor

William Hahn

Publication

Hagel et al Cancer Res. 2022 Dec 22:CAN-22-2245. doi

Insert

sgSMARCA4 guide 2 (SMARCA4 Human)

Use

Lentiviral

Available since

Jan. 3, 2023

Availability

Academic Institutions and Nonprofits only

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HP-Cas9hGem-Ade2-LEU2-LINEAR

Plasmid

#174839

Purpose

pRS414 backbone containing LINEAR fragment targeting ADE2 in H. polymorpha

Depositor

Zengyi Shao

Publication

Ploessl et al Nat Chem Biol. 2021 Oct 28. pii: 10.1038

Insert

HH-gRNA-HDV targetting ADE2 in Ogataea (para)polymorpha

Use

CRISPR and Synthetic Biology

Expression

Bacterial and Yeast

Promoter

TDH3p

Available since

Jan. 5, 2022

Availability

Academic Institutions and Nonprofits only

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pMXS-IRES-Blast HA-GPAT4

Plasmid

#173168

Purpose

Retroviral vector to express sgRNA resistant HA tagged human GPAT4

Depositor

Kivanc Birsoy

Publication

Zhu et al Mol Cell. 2019 Apr 4;74(1):45-58.e7. doi

Insert

Glycerol-3-Phosphate Acyltransferase 4 (GPAT4 Human)

Use

Retroviral

Tags

HA

Mutation

Synonymous mutations at sgRNA sites

Promoter

MMLV

Available since

Aug. 27, 2021

Availability

Academic Institutions and Nonprofits only

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pGEM-sgMUC1_dual-MTS-3x-Set I

Plasmid

#162763

Purpose

Separately expressing 3 unique sgMUC1_dual-MTS (SetI)

Depositor

Antony K Chen

Publication

Mao et al Nucleic Acids Res. 2019 Nov 18;47(20):e1

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

sgMUC1_dual-MTS_1; sgMUC1_dual-MTS_2; sgMUC1_dual-MTS_3

Expression

Mammalian

Promoter

U6

Available since

Jan. 6, 2021

Availability

Academic Institutions and Nonprofits only

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