Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more



Description mitogen-activated protein kinase kinase 1
Also known as MAPKK1, MEKK1, Mek1, Prkmk1
Species Mus musculus
Entrez ID 26395
MGC ID BC054754

Addgene Alerts

You can receive an email alert when new materials related to this gene are available at Addgene.

Log in to manage alerts

Plasmids containing this gene, or a homologous gene.

ID Plasmid Gene/Insert PI
14746MEK1-GFPMEK1 (Homo sapiens) Seger
18885pYBS369Ste7 (Saccharomyces cerevisiae) Elion
18886pYBS370Ste7 (Saccharomyces cerevisiae) Elion
21193L1E-1Mek1 (Homo sapiens) Khavari
21195LDNMek1 (Homo sapiens) Khavari
21196LZRS-Mek1-wt1 (wt1)Mek1 (Homo sapiens) Khavari
21207CC2Mek1 (Homo sapiens) Khavari
21208W1Mek1 (Homo sapiens) Khavari
21209DN9Mek1 (Homo sapiens) Khavari
23406pDONR223-MAP2K1MAP2K1 (Homo sapiens) Hahn
31166782 pMEActMEKMEK (Homo sapiens) Lawson
31202pDONR223-MEKDDMAPKK1 (Homo sapiens) Root
31880783 pCScherryActMEKMEK1 (Homo sapiens) Lawson
39194pCMV-myc-ERK2-MEK1_fusionERK2-MEK1 Fusion (Homo sapiens) Cobb
39197pCMV-myc-ERK2-L4A-MEK1_fusionERK2-MEK1 Fusion (Homo sapiens) Cobb
39212pET-His6-ERK2-MEK1_R4F_coexpressionMek1 R4F (Homo sapiens), Erk2 (Rattus norvegicus) Cobb
40774Mek1MKK1 (Homo sapiens) Maly
40807pMCL-HA-MAPKK1-G1C [delta(44-51)/S218E/S222D]MAP2K1 (Homo sapiens) Ahn
40808pMCL-HA-MAPKK1-WTMAP2K1 (Homo sapiens) Ahn
40809pMCL-HA-MAPKK1-11A55B [S218E/S222D]MAP2K1 (Homo sapiens) Ahn
40810pMCL-HA-MAPKK1-R4F [delta(31-51)/S218E/S222D]MAP2K1 (Homo sapiens) Ahn
40811pMCL-HA-MAPKK1-8E (K97M)MAP2K1 (Homo sapiens) Ahn
47576pGEX-4T-1 3xHA-MEK1-DDMEK1-DD (Mus musculus) Janes
52681pGEX4T2-Ste7-EESte7 (Saccharomyces cerevisiae) Turk
53159pGEX6P1-HA-MEK1MEK1 (Homo sapiens) Counter
53161pWZLblasti-HA-MEK1MEK1 (Homo sapiens) Counter
53163pGEX6P1-HA-MEK1 CBMMEK1 (Homo sapiens) Counter
53164pGEX6P1-HA-MEK1 C121SMEK1 (Homo sapiens) Counter
53165pWZLblasti-HA-MEK1 C121SMEK1 (Homo sapiens) Counter
53176pBABEpuro-HA-MEK1-MEK5DDMEK1 (1-201)-MEK5 (498–1344) fusion (Homo sapiens) Counter
53177pWZLblasti-HA-MEK1-MEK5DDMEK1 (1-201)-MEK5 (498–1344) fusion (Homo sapiens) Counter
53179pSUPER-retro-puro-tetO-Mek1-shRNAMEK1 (Mus musculus) Counter
53195pBABEpuro-HA-MEK1MEK1 (Homo sapiens) Counter
53196pBABEpuro-HA-MEK1 CBMMEK1 (Homo sapiens) Counter
53197pBABEpuro-HA-MEK1 C121SMEK1 (Homo sapiens) Counter
53225PCRT7 tetR pLtetO MBP-MEK1 XX AmpMEK1 (Homo sapiens) Rinehart
64604MEK1 (S218D,S222D)-pcw107MAP2K1 (Homo sapiens) Sabatini
64650MEK1-pcw107-V5MAP2K1 (Homo sapiens) Sabatini
68300MBP-MEK1MBP-MEK1 (Homo sapiens) Rinehart
68301MBP-MEK1 S218TAGMBP-MEK1 S218TAG (Homo sapiens) Rinehart
68302MBP-MEK1 S222TAGMBP-MEK1 S222TAG (Homo sapiens) Rinehart
70405R777-E121 Hs.MAP2K1MAP2K1 (Homo sapiens) Esposito
70406R777-E122 Hs.MAP2K1-nostopMAP2K1 (Homo sapiens) Esposito
72567shMEK1/2 puroMEK1/2 (Mus musculus) Janes
72568shMEK1/2 v2 puroMEK1/2 (Mus musculus) Janes
72569shMEK1/2 neoMEK1/2 (Mus musculus) Janes
72570shMEK1/2 v2 neoMEK1/2 (Mus musculus) Janes
81669pDONR223_MAP2K1_p.C121SMAP2K1 (Homo sapiens) Boehm
81672pDONR223_MAP2K1_p.L177MMAP2K1 (Homo sapiens) Boehm
81695pDONR223_MAP2K1_p.K57TMAP2K1 (Homo sapiens) Boehm
81703pDONR223_MAP2K1_p.P124SMAP2K1 (Homo sapiens) Boehm
81729pDONR223_MAP2K1_p.E203KMAP2K1 (Homo sapiens) Boehm
81920pDONR223_MAP2K1_WTMAP2K1 (Homo sapiens) Boehm
82139pDONR223_MAP2K1_WTMAP2K1 (Homo sapiens) Boehm
82177pDONR223_MAP2K1_p.S218D_S222DMAP2K1 (Homo sapiens) Boehm
86141pMXs2-MEK1MEK1 (Homo sapiens) Sabatini
89361pLL3.7m-psMEK1psMEK1 (Homo sapiens) Lin
89362pLL3.7m-psMEK1tightpsMEK1tight (Homo sapiens) Lin
107973pcDNA3-MKK1MKK1 (Homo sapiens) Krebs
107974pcDNA3-MKK1K97AMKK1 K97A (Homo sapiens) Krebs
116427pHAGE-MAP2K1-K57NMAP2K1 (Homo sapiens) Scott
116428pHAGE-MAP2K1-P124SMAP2K1 (Homo sapiens) Scott
116429pHAGE-MAP2K1-S222AMAP2K1 (Homo sapiens) Scott
116757pHAGE-MAP2K1MAP2K1 (Homo sapiens) Scott
164638MEK1C222mitogen-activated protein kinase kinase 1 (Homo sapiens) Davis
164639MEK1C218mitogen-activated protein kinase kinase 1 (Homo sapiens) Davis
164640MEK1C218C222mitogen-activated protein kinase kinase 1 (Homo sapiens) Davis
164641Δ1-60MEK1C222N-terminal truncated mitogen-activated protein kinase kinase 1 (Homo sapiens) Davis
164643Δ1-60MEK1C218N-terminal truncated mitogen-activated protein kinase kinase 1 (Homo sapiens) Davis
164645Δ1-60MEK1C218C222N-terminal truncated mitogen-activated protein kinase kinase 1 (Homo sapiens) Davis
170240LV_EF1a_MEK1(S218D,S222D)-P2A-Hygro_BarcodeMAP2K1 (Homo sapiens) Mali
194882pLX311-GFP-MEKDDMEKDD (Homo sapiens) Rosenbluh