We narrowed to 16,121 results for: grna

Showing: 11601 - 11620 of 16121 results

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pLentiCRISPRv1-sgAAVS1

Plasmid

#83906

Purpose

stable knockout

Depositor

David Sabatini

Publication

Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

Insert

adeno-associated virus integration site 1 (AAVS1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

Oct. 21, 2016

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pSico-shRaptor

Plasmid

#81086

Purpose

conditional expression of an shRNA targeting murine Raptor

Depositor

Angelique Bordey

Publication

Hartman et al Cell Rep. 2013 Oct 31;5(2):433-44. doi:

Insert

Raptor shRNA (Rptor Mouse)

Use

Cre/Lox, Lentiviral, and RNAi

Expression

Mammalian

Promoter

U6

Available since

Sept. 27, 2016

Availability

Academic Institutions and Nonprofits only

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pSico-shRheb

Plasmid

#81087

Purpose

conditional expression of an shRNA targeting murine Rheb

Depositor

Angelique Bordey

Publication

Hartman et al Cell Rep. 2013 Oct 31;5(2):433-44. doi:

Insert

Rheb shRNA (Rheb Mouse)

Use

Cre/Lox, Lentiviral, and RNAi

Expression

Mammalian

Promoter

U6

Available since

Sept. 21, 2016

Availability

Academic Institutions and Nonprofits only

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D. vulgaris sp2 CRISPR/pACYCDuet-1

Plasmid

#81186

Purpose

Expresses CRISPR array containing 3 copies of Desulfovibrio vulgaris spacer 2 and flanking repeats in E. coli

Depositor

Jennifer Doudna

Publication

Hochstrasser et al Mol Cell. 2016 Sep 1;63(5):840-51. doi:

Insert

Synthetic CRISPR array (3 copies of D. vulgaris spacer #2 flanked by repeats)

Use

CRISPR

Tags

None

Expression

Bacterial

Promoter

T7

Available since

Sept. 15, 2016

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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shCDK4/6(1)

Plasmid

#73554

Purpose

vector encoding both shRNA against CDK4(1) and shRNA against CDK6(1)

Depositor

Gerardo Ferbeyre

Publication

Acevedo et al Cancer Res. 2016 Jun 1;76(11):3252-64. d

Insert

shRNA against CDK4 + shRNA against CDK6

Use

Retroviral

Expression

Mammalian

Promoter

LTR

Available since

Aug. 8, 2016

Availability

Academic Institutions and Nonprofits only
shMEK1/2 puro

Plasmid

#72567

Purpose

Hairpin targeting MEK1 and MEK2 (murine).

Depositor

Kevin Janes

Publication

Jensen et al Cell Syst. 2016 Feb 24;2(2):112-121.

Insert

MEK1/2 (Map2k1, Map2k2 Mouse)

Use

Lentiviral

Tags

None

Expression

Mammalian

Available since

July 12, 2016

Availability

Academic Institutions and Nonprofits only

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TRCN0000072254

Plasmid

#78161

Purpose

Luciferase control

Depositor

William Hahn

Publication

Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

Insert

Luciferase

Use

RNAi

Promoter

hU6

Available since

June 22, 2016

Availability

Academic Institutions and Nonprofits only
plentiCRISPR-sgGOT1

Plasmid

#72874

Purpose

The lentiviral sgGOT1 vector was generated via ligation of hybridized oligos (below) into lentiCRISPR-v1 vector linearized with BsmBI using Gibson assembly (NEB).

Depositor

David Sabatini

Publication

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Insert

sgGOT1

Use

Lentiviral

Available since

March 4, 2016

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles
pLKO_HOXB13_#2

Plasmid

#70094

Purpose

Expression of shRNA to human HOXB13, puromycin selection

Depositor

William Hahn

Publication

Pomerantz et al Nat Genet. 2015 Nov;47(11):1346-51. doi:

Insert

HOXB13 (HOXB13 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Promoter

U6

Available since

Nov. 6, 2015

Availability

Academic Institutions and Nonprofits only
pU6_(Gluc)_INT(GenPurpClon)

Plasmid

#68433

Purpose

General Purpose cloning vector for "INT"-like constructs under U6-promoter expression.

Depositor

John Rinn

Publication

Shechner et al Nat Methods. 2015 Jul;12(7):664-70. doi:

Insert

INT construct

Use

CRISPR; Cloning vector for generating int-like co…

Expression

Mammalian

Promoter

human U6

Available since

Oct. 5, 2015

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles

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pBrain-GFP-shTACC3

Plasmid

#59355

Purpose

Knocks down TACC3 in mammalian cells via shRNA and co-expresses GFP.

Depositor

Stephen Royle

Publication

Booth et al EMBO J. 2011 Mar 2;30(5):906-19. doi: 10

Insert

EGFP

Use

RNAi

Expression

Mammalian

Available since

Dec. 5, 2014

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pSUPERretro-Sirt7 shRNA2

Plasmid

#53145

Purpose

shRNAi vector for Sirt7

Depositor

Katrin Chua

Publication

Barber et al Nature. 2012 Jul 5;487(7405):114-8. doi:

Insert

Sirt7

Use

RNAi and Retroviral

Expression

Mammalian

Promoter

H1 RNA polymerase III

Available since

May 9, 2014

Availability

Academic Institutions and Nonprofits only
pSUPERretro-Sirt7 shRNA1

Plasmid

#53144

Purpose

shRNAi vector for Sirt7

Depositor

Katrin Chua

Publication

Barber et al Nature. 2012 Jul 5;487(7405):114-8. doi:

Insert

Sirt7

Use

RNAi and Retroviral

Expression

Mammalian

Promoter

H1 RNA polymerase III

Available since

May 9, 2014

Availability

Academic Institutions and Nonprofits only
MSCV-shCasp2-IRES-GFP

Plasmid

#52061

Purpose

stable knockdown of Caspase-2 in mammalian cells

Depositor

Tyler Jacks, Trudy Oliver

Publication

Oliver et al Mol Cell. 2011 Jul 8;43(1):57-71. doi: 1

Insert

Caspase-2 shRNA (CASP2 Human)

Use

Retroviral

Tags

IRES-EGFP

Expression

Mammalian

Available since

March 13, 2014

Availability

Academic Institutions and Nonprofits only
pLKO.1-lincRNA-RoR-sh1 (Linc-sh1)

Plasmid

#45764

Depositor

George Daley

Publication

Loewer et al Nat Genet. 2010 Dec;42(12):1113-7. Epub

Insert

lincRNA-RoR-shRNA1 (LINC-ROR Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

Aug. 12, 2013

Availability

Academic Institutions and Nonprofits only

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shBCL2L1 # 1

Plasmid

#42551

Depositor

William Hahn

Publication

Rosenbluh et al Cell. 2012 Dec 21;151(7):1457-73. doi: 1

Insert

shBCL2L1 (BCL2L1 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

May 10, 2013

Availability

Academic Institutions and Nonprofits only
shBCL2L1 # 2

Plasmid

#42552

Depositor

William Hahn

Publication

Rosenbluh et al Cell. 2012 Dec 21;151(7):1457-73. doi: 1

Insert

shBCL2L1 (BCL2L1 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

May 10, 2013

Availability

Academic Institutions and Nonprofits only
pLKO-shcIAP1-B

Plasmid

#44131

Depositor

William Hahn

Publication

Shen et al Mol Cell Biol. 2012 Dec;32(23):4756-68.

Insert

c-IAP1 (BIRC2 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

April 10, 2013

Availability

Academic Institutions and Nonprofits only
pLKO.1puro-shKIBRA-A

Plasmid

#40888

Depositor

Paul Reynolds

Publication

Moleirinho et al Oncogene. 2012 May 21. doi: 10.1038/onc.

Insert

shKIBRA-A (WWC1 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

March 7, 2013

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
shTCF7L2 # 1

Plasmid

#42557

Depositor

William Hahn

Publication

Rosenbluh et al Cell. 2012 Dec 21;151(7):1457-73. doi: 1

Insert

shTCF7L2 (TCF7L2 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available since

Feb. 14, 2013

Availability

Academic Institutions and Nonprofits only