We narrowed to 15,451 results for: grn

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pU6-tevopreq1-FXR1-G266E

Plasmid

#225482

Purpose

Express epegRNA for FXR1

Depositor

Christine Mayr

Publication

Chen et al Cell. 5 August 2024. doi: 10.1016/j.cell

Insert

epegRNA for editing FXR1-G266E (FXR1 Human)

Use

CRISPR

Promoter

hU6

Available since

Oct. 10, 2024

Availability

Academic Institutions and Nonprofits only

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pENTR223-CMV-Cre-U6-sgC0111-U6-sgRb1-U6-sgTrp53-U6-sgRbl2

Plasmid

#209062

Purpose

Entry vector that encodes sgRNAs against mouse Rb1, Trp53, Rbl2, and a non-targeting sgRNA (C0111) and CMV Cre recombinase.

Depositor

Matthew Oser

Publication

Duplaquet et al Nat Cell Biol. 2023 Sep;25(9):1346-1358.

Insert

non-targeting sgRNA (C0111)

Use

Gateway vector to be used for lr reaction

Promoter

U6

Available since

Dec. 20, 2023

Availability

Academic Institutions and Nonprofits only

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pAAV_3x_U6_mmp25_CAG_nlsTagBFP2

Plasmid

#247935

Purpose

Targeting mmp25 gene in vivo by adeno-associated viral vector-mediated delivery

Depositor

Benoit Vanhollebeke

Publication

Panji et al Commun Biol. 2026 Feb 25;9(1):479. doi:

Insert

mmp25 sgRNAs (Mmp25 Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Tags

nls-TagBFP2

Expression

Mammalian

Promoter

U6

Available since

June 1, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV_3x_U6_Slc2a1_CAG_nlsTagBFP2

Plasmid

#247936

Purpose

Targeting Slc2a1 gene in vivo by adeno-associated viral vector-mediated delivery

Depositor

Benoit Vanhollebeke

Publication

Panji et al Commun Biol. 2026 Feb 25;9(1):479. doi:

Insert

Slc2a1 sgRNAs (Slc2a1 Mouse)

Use

AAV, CRISPR, and Mouse Targeting

Tags

nls-TagBFP2

Expression

Mammalian

Promoter

U6

Available since

June 1, 2026

Availability

Academic Institutions and Nonprofits only

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LRG-2.1T-sgTAF12(human)#4.5

Plasmid

#105987

Purpose

lentivirally express gRNA targeting human TAF12 HFD with GFP marker

Depositor

Christopher Vakoc

Publication

Xu et al Cancer Cell. 2018 Jan 8;33(1):13-28.e8.

Insert

gRNA targeting human TAF12-HFD

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

July 3, 2018

Availability

Academic Institutions and Nonprofits only

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KLF17-CRa1-Lsg-MS2

Plasmid

#247476

Purpose

sgRNA1 for KLF17 activation cloned into LsgRNA-MS2 backbone

Depositor

Ting Zhou

Publication

Wu et al Stem Cell Reports. 2025 Apr 25:102499. d

Insert

sgRNA1 targeting KLF17 promoter (KLF17 Synthetic, Human)

Use

CRISPR

Expression

Mammalian

Available since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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KLF17-CRa2-Lsg-MS2

Plasmid

#247477

Purpose

gRNA2 for KLF17 activation cloned into LsgRNA-MS2 backbone

Depositor

Ting Zhou

Publication

Wu et al Stem Cell Reports. 2025 Apr 25:102499. d

Insert

sgRNA2 targeting KLF17 promoter (KLF17 Synthetic, Human)

Use

CRISPR

Expression

Mammalian

Available since

Oct. 23, 2025

Availability

Academic Institutions and Nonprofits only

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PEA1-Nuclease

Plasmid

#176528

Purpose

Delivers all prime editing nuclease components in a single plasmid

Depositor

Paul Thomas

Publication

Adikusuma et al Nucleic Acids Res. 2021 Sep 17. pii: 637

Insert

CbH-Cas9-RT, hU6-pegRNA (Bbs1 gate), hU6-sgRNA (Bbs1 gate)

Use

CRISPR

Expression

Mammalian

Mutation

GC to CA point mutation in SpCas9 to restore nucl…

Promoter

CbH for Cas9, hU6 for gRNAs

Available since

Dec. 16, 2021

Availability

Academic Institutions and Nonprofits only

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pU6-sgT-REX17_EF1a-Puro-T2A-BFP

Plasmid

#195501

Purpose

Lentiviral BFP expression vector bearing a sgRNA targeting the promoter of human T-REX17

Depositor

Alexander Meissner

Publication

Landshammer et al Elife. 2023 Jan 31;12:e83077. doi: 10.75

Insert

sgRNA

Use

CRISPR and Lentiviral

Tags

BFP, Puro, and T2A

Expression

Mammalian

Available since

Feb. 2, 2023

Availability

Academic Institutions and Nonprofits only

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Direct-seq_lentiGuide-Puro-Tetra Loop-8A8G

Plasmid

#157982

Purpose

Expresses programmed gRNA scaffold from U6 promoter. Programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screen (Direct-seq). 3rd generation lentiviral backbone.

Depositor

Lijia Ma

Publication

Song et al Genome Biol. 2020 Jun 8;21(1):136. doi:

Insert

S. pyogenes sgRNA cassette (Tetra-8A8G)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

May 10, 2021

Availability

Academic Institutions and Nonprofits only

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Adeno BN

Plasmid

#101823

Purpose

Adenovirus for the expression of gRNAs targeting intron 13 of murine Bcan and intron 10 of murine Ntrk1

Depositor

Andrea Ventura

Publication

Cook et al Nat Commun. 2017 Jul 11;8:15987. doi: 10

Insert

U6_sgRNA(Bcan)_U6_sgRNA(Ntrk1)_CBh_FLAG-Cas9 (Bcan, Ntrk1 Mouse)

Use

Adenoviral

Tags

FLAG-Cas9

Available since

Nov. 8, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
pXPR_003.gEZH2

Plasmid

#220318

Purpose

Expresses guide RNA for CRISPR/Cas9 knockout of EZH2 for knockout/rescue experiments in mammalian cells.

Depositor

Chen Davidovich

Publication

Gail et al Nat Genet. 2024 May 14. doi: 10.1038/s41

Insert

EZH2 gRNA (EZH2 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Promoter

U6

Available since

June 12, 2024

Availability

Academic Institutions and Nonprofits only

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CROPseq-Puro-2xMS2

Plasmid

#212627

Purpose

MS2 hairpin-containing expression vector and sgRNA entry plasmid for the directed export of barcode transcripts in Gag-MCP virus-like particles

Depositor

Paul Blainey

Publication

Najia et al Cell. 2026 Sep 1:S0092-8674(26)00932-3.

Insert

EF1a-PuroR-2xMS2-WPRE-hU6-sgRNA

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

EF1a

Available since

Nov. 19, 2024

Availability

Academic Institutions and Nonprofits only

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LRG-neo-sgTAF12(mouse)#4.1

Plasmid

#105588

Purpose

lentivirally express gRNA targeting human TAF12 HFD with GFP marker and neo resistance

Depositor

Christopher Vakoc

Publication

Xu et al Cancer Cell. 2018 Jan 8;33(1):13-28.e8.

Insert

gRNA targeting TAF12 HFD

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

March 5, 2018

Availability

Academic Institutions and Nonprofits only

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pLV-KLF17-CRa1-MS2

Plasmid

#251117

Purpose

sgRNA1 for KLF17 activation cloned into lenti sgRNA(MS2)_puro backbone

Depositor

Ting Zhou

Publication

Wu et al Stem Cell Reports. 2025 Apr 25:102499. d

Insert

sgRNA1 targeting KLF17 promoter (KLF17 Synthetic, Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLV-KLF17-CRa2-MS2

Plasmid

#251118

Purpose

sgRNA2 for KLF17 activation cloned into lenti sgRNA(MS2)_puro backbone

Depositor

Ting Zhou

Publication

Wu et al Stem Cell Reports. 2025 Apr 25:102499. d

Insert

sgRNA2 targeting KLF17 promoter (KLF17 Synthetic, Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

U6

Available since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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LRG-2.1T-neo-sgMYB(human)#4.9

Plasmid

#105591

Purpose

lentivirally express gRNA targeting human MYB DBD with GFP marker and neo resistance

Depositor

Christopher Vakoc

Publication

Xu et al Cancer Cell. 2018 Jan 8;33(1):13-28.e8.

Insert

gRNA targeting human MYB DBD

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

March 5, 2018

Availability

Academic Institutions and Nonprofits only

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LRG-2.1T-neo-sgMYB(human)#5.2

Plasmid

#105592

Purpose

lentivirally express gRNA targeting human MYB DBD with GFP marker and neo resistance

Depositor

Christopher Vakoc

Publication

Xu et al Cancer Cell. 2018 Jan 8;33(1):13-28.e8.

Insert

gRNA targeting human MYB DBD

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available since

March 5, 2018

Availability

Academic Institutions and Nonprofits only

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Adeno FT

Plasmid

#101824

Purpose

Adenovirus for the expression of gRNAs targeting intron 17 of murine Fgfr3 and intron 6 of murine Tacc3

Depositor

Andrea Ventura

Publication

Cook et al Nat Commun. 2017 Jul 11;8:15987. doi: 10

Insert

U6_sgRNA(Fgfr3)_U6_sgRNA(Tacc3)_CBh_FLAG-Cas9 (Fgfr3, Tacc3 Mouse)

Use

Adenoviral

Tags

FLAG-Cas9

Promoter

U6 and CBh

Available since

Nov. 8, 2017

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article
pRP[CRISPR]-EGFP/Puro-hCas9-U6>(long left)-U6>(long right)

Plasmid

#216871

Purpose

This plasmid contains hCas9 and two gRNAs that can excise the genomic area around the mouse mdx mutation in dystrophin's exon 23

Depositor

Ori Bar-Nur

Publication

Lenardic et al J Clin Invest. 2024 May 7:e166998. doi:

Insert

Cas9, gRNA Long.L, gRNA Long.R (Dmd Mouse)

Use

CRISPR

Mutation

mdx mutation in mouse dystrophin

Available since

June 3, 2024

Availability

Academic Institutions and Nonprofits only

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