168,238 results

1. pAAVS1-NDi-CRISPRi (Gen2)

   Plasmid

   #73498

   Purpose

   Dox-inducible CRISPR interference (CRISPRi) knock in construct into the AAVS1 locus

   Depositor

   Bruce Conklin

   Article

   Mandegar et al Cell Stem Cell. 2016 Apr 7;18(4):541-53.

   Inserts

   dCas9-KRAB
   rtTA
   

   Use

   CRISPR

   Tags

   HA, KRAB, and NLS

   Expression

   Mammalian

   Mutation

   D10A, H840A (catalytically deactivated Cas9)

   Promoter

   CAG and TRE3G

   Available Since

   Dec. 7, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLentiPGK Puro DEST JNKKTRClover

   Plasmid

   #59151

   Purpose

   Lentiviral vector to express JNK KTR mClover under PGK promoter (With Puromycin Resistance)

   Depositor

   Markus Covert

   Article

   Regot et al Cell. 2014 Jun 19;157(7):1724-34. doi: 1

   Insert

   JNK Kinase Translocation Reporter (MAPK8 Human, Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   PGK

   Available Since

   Sept. 18, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. pXPR_047

   Plasmid

   #107145

   Purpose

   measures Cas9 activity

   Depositor

   David Root

   Insert

   GFP + sgRNA for GFP
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   March 8, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-DJ-N589X

   Plasmid

   #130878

   Purpose

   Encodes the AAV-DJ capsid with the N589 residue replaced with a TAG stop codon

   Depositor

   Prashant Mali

   Article

   Katrekar et al Sci Rep. 2018 Feb 26;8(1):3589. doi: 10.

   Insert

   AAV-DJ cap N589X
   

   Use

   AAV

   Expression

   Mammalian

   Mutation

   N589X

   Promoter

   Unknown

   Available Since

   Sept. 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. AAV-CMV-Nrf2

   Plasmid

   #67636

   Purpose

   AAV vector expressing Nrf2 gene

   Depositor

   Connie Cepko

   Article

   Xiong et al J Clin Invest. 2015 Apr;125(4):1433-45.

   Insert

   Nrf2 (Nfe2l2 Mouse)
   

   Use

   AAV

   Promoter

   CMV

   Available Since

   Aug. 24, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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6. hSyn1 HRP-TM

   Plasmid

   #231500

   Purpose

   Expressing HRP on the cell surface of neurons

   Depositor

   Baljit Khakh

   Article

   Wu et al Neuron. 2025 Jun 5:S0896-6273(25)00366-6

   Insert

   HRP
   

   Use

   AAV

   Tags

   Igk, HA, Myc, PDGFR-beta transmembrane domain

   Expression

   Mammalian

   Available Since

   June 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. FUGW-APOE-E3-T2A-mCherry

   Plasmid

   #190808

   Purpose

   Express APOE E3 allele from Ubiquitin C promoter, co-expressing mCherry

   Depositor

   Ronald Hart

   Insert

   APOE (APOE Human)
   

   Use

   Lentiviral

   Mutation

   E3

   Promoter

   Ubi C

   Available Since

   Sept. 22, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pCAGGs-RFP

   Plasmid

   #127347

   Purpose

   Expresses RFP constitutively via the CAGGS promoter in mammalian cells

   Depositor

   Phil Sharp

   Insert

   Red Fluorescent Protein
   

   Expression

   Mammalian

   Promoter

   CAGGS Promoter

   Available Since

   Dec. 10, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV_BiSSTe4_dTomato_nlsdTomato (AAV PHP.eB)

   Viral Prep

   #213944-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from pAAV_BiSSTe4_dTomato_nlsdTomato (#213944). In addition to the viral particles, you will also receive purified pAAV_BiSSTe4_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the SST interneuron-targeting enhancer E4. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

   Tags

   dTomato

   Available Since

   Dec. 2, 2024

   Availability

   Academic Institutions and Nonprofits only

10. GST-RH▲-MNase

    Plasmid

    #136292

    Purpose

    Expression of catalytic inactive RNase H fused to micrococcal nuclease

    Depositor

    Kavitha Sarma

    Article

    Yan et al Cell Rep. 2019 Oct 29;29(5):1369-1380.e5

    Insert

    RNase HI-D10R-E48R and MNase
    

    Expression

    Bacterial

    Available Since

    Feb. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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