We narrowed to 18,031 results for: Mut

1. pTwist-SARS-CoV-2 Spike-deltaC18 (P.2/B.1.1.248) - No RBD Mutations

   Plasmid

   #212385

   Purpose

   Encodes SARS-CoV-2 spike D614G,V1176F for pseudovirus production

   Depositor

   Alejandro Balazs

   Article

   Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0

   Insert

   SARS-CoV-2 Spike D614G,V1176F (S Severe acute respiratory syndrome coronavirus 2)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   D614G,V1176F

   Promoter

   CAG

   Available Since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAc5.1-EGFP-Vasa 463-661 MUT (F504E) (HK196)

   Plasmid

   #206434

   Purpose

   Vasa 463-661 expression in Schneider cells for imaging

   Depositor

   Mandy Jeske

   Article

   Salgania et al Nat Commun. 2024 Apr 3;15(1):2875. doi:

   Insert

   Vasa 463-661 (vas Fly)
   

   Use

   Tags

   EGFP

   Expression

   Insect

   Mutation

   F504E

   Promoter

   Available Since

   July 30, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAc5.1B-lambdaN-HA-HsTNRC6C_1207-1609-M2WA-CIM1-2mut-F1389A_T

   Plasmid

   #147636

   Purpose

   Insect Expression of HsTNRC6C_1207-1609-M2WA-CIM1-2mut-F1389A

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

   Insert

   HsTNRC6C_1207-1609-M2WA-CIM1-2mut-F1389A (TNRC6C Human)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   Promoter

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAc5.1B-EGFP-CeAIN2_254-400-DmGW182_635-1384-CIM1mut-F961A_S

   Plasmid

   #147514

   Purpose

   Insect Expression of CeAIN2_254-400-DmGW182_635-1384-CIM1-F961A

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

   Insert

   CeAIN2_254-400-DmGW182_635-1384-CIM1-F961A (gw Human, Nematode)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   Deletion of 2 AA (SD) at position 378-379 compare…

   Promoter

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCIneo-lambdaN-HA-HsTNRC6A-M2WA-CIM1-2mut-F1359A-siRNAres_S

   Plasmid

   #147516

   Purpose

   Insect Expression of HsTNRC6A-M2WA-CIM1-2mut-F1359A-siRNAres

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

   Insert

   HsTNRC6A-M2WA-CIM1-2mut-F1359A-siRNAres (TNRC6A Human)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   one non silent mutation K1578E compared to the se…

   Promoter

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAc5.1B-EGFP-CeAIN2_254-400-DmGW182_635-1384-M2WA-CIM1mut_R

   Plasmid

   #147388

   Purpose

   Insect Expression of CeAIN2_254-400-DmGW182_635-1384-M2WA-CIM1mut

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

   Insert

   CeAIN2_254-400-DmGW182_635-1384-M2WA-CIM1mut (gw Fly, Nematode)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   Deletion of 2 AA (SD) at position 378-379 compare…

   Promoter

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAc5.1B-EGFP-CeAIN2_254-400-DmGW182_635-1384-P-GLmut-F961A_R

   Plasmid

   #147391

   Purpose

   Insect Expression of CeAIN2_254-400-DmGW182_635-1384-P-GLmut-F961A

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

   Insert

   CeAIN2_254-400-DmGW182_635-1384-P-GLmut-F961A (gw Fly)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   Deletion of 2 AA (SD) at position 378-379 compare…

   Promoter

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAc5.1B-EGFP-CeAIN2_254-400-DmGW182_635-1384-CIM1-mut_R

   Plasmid

   #147385

   Purpose

   Insect Expression of CeAIN2_254-400-DmGW182_635-1384-CIM1-mut

   Depositor

   Elisa Izaurralde

   Article

   Huntzinger et al Nucleic Acids Res. 2013 Jan;41(2):978-94

   Insert

   CeAIN2_254-400-DmGW182_635-1384-CIM1-mut (gw Fly, Nematode)
   

   Use

   Tags

   Expression

   Insect

   Mutation

   Deletion of 2 AA (SD) at position 378-379 compare…

   Promoter

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-EF1α-Flex/3'USS-ChRWR/Venus(ATG mut)

   Plasmid

   #197891

   Purpose

   Can be used to generate AAV virus that will express ChRWR/Venus in the presence of Cre and the leakage expression is significantly reduced without Cre

   Depositor

   Kazuto Kobayashi

   Article

   Matsushita et al Cell Rep Methods. 2023 Jan 18;3(2):10039

   Insert

   ChRWR/Venus
   

   Use

   AAV

   Tags

   Expression

   Mutation

   N/A

   Promoter

   EF1a

   Available Since

   March 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCAG-GST-hFIP200(Delta641-779, 1363-1370Mut)-MBP

    Plasmid

    #190039

    Purpose

    Expression of FIP200 mutant

    Depositor

    James Hurley

    Article

    Shi et al Elife. 2020 Aug 10;9. pii: 59099. doi: 1

    Insert

    FIP200 (RB1CC1 Human)
    

    Use

    Tags

    GST and MBP

    Expression

    Mammalian

    Mutation

    (641-779)deletion & 1363 RDKDLIES 1370 to GSS…

    Promoter

    CMV

    Available Since

    Nov. 8, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pMSCV-IRES-GFP-dog-Caspase-1/4a-triple mutant-H342D_K345M_K379T

    Plasmid

    #183364

    Purpose

    Stable expression of mammalian inflammatory caspase gene in mammalian cells by retroviral transduction

    Depositor

    Jonathan Kagan

    Article

    Devant et al Sci Immunol. 2021 Aug 10;6(62). doi: 10.

    Insert

    Caspase-1/4a (CASP4 Canis lupus familiaris)
    

    Use

    Retroviral

    Tags

    Myc

    Expression

    Mutation

    H342D_K345M_K379T

    Promoter

    MESV

    Available Since

    May 5, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. MSCV-mouse Mdm2 mutant M3 (399-489)-IRES-GFP

    Plasmid

    #180490

    Purpose

    Role of Mdm2 variants in tumorigenesis

    Depositor

    Martine Roussel

    Article

    Dang et al Cancer Res. 2002 Feb 15;62(4):1222-30.

    Inserts

    Mouse Mdm2 mutant
    Mouse Mdm2 mutant
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    399-489

    Promoter

    MSCV

    Available Since

    March 29, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. MSCV-mouse Mdm2 mutant M2 (299-489)-IRES-GFP

    Plasmid

    #180489

    Purpose

    Role of Mdm2 variants in tumorigenesis

    Depositor

    Martine Roussel

    Article

    Dang et al Cancer Res. 2002 Feb 15;62(4):1222-30.

    Insert

    Mouse Mdm2 mutant
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    299-489

    Promoter

    MSCV

    Available Since

    March 29, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLV-EGFP-PolB-(K35A/K68A/K72A)-PAMmut-Hygro

    Plasmid

    #176089

    Purpose

    EGFP fused the N-terminus of POLB containing the mutations Lys35Ala, Lys68Ala, and Lys72Ala, a mutation in the PAM site used by POLB gRNA1 & a hygromycin resistance cassette

    Depositor

    Robert Sobol

    Article

    Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

    Insert

    PolB (POLB Human)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Mutations in Lys35 to Ala, Lys68 to Ala, and Lys7…

    Promoter

    CMV

    Available Since

    Jan. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. PB-CuO-V5-CASC3 siRes 110-480 188/218-mut

    Plasmid

    #158544

    Purpose

    For PiggyBac-mediated integration of V5-tagged siRNA-resistant EJC-binding deficient CASC3 110-480

    Depositor

    Niels Gehring

    Article

    Gerbracht et al Nucleic Acids Res. 2020 Jul 4. pii: 5867

    Insert

    CASC3; BTZ; MLN51 (CASC3 Human)
    

    Use

    Tags

    V5

    Expression

    Mammalian

    Mutation

    Amino acids 110-480, C-terminal deletion, F188D, …

    Promoter

    CMV

    Available Since

    Oct. 21, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. pX330-Flag-SpCas9-HF1 (without sgRNA; with silent mutations)

    Plasmid

    #126755

    Purpose

    Expression plasmid for human codon-optimized increased fidelity SpCas9-HF1 (without U6-sgRNA coding sequence, with silent mutations)

    Depositor

    Ervin Welker

    Article

    Kulcsar et al Nat Commun. 2020 Mar 6;11(1):1223. doi:

    Insert

    SpCas9-HF1
    

    Use

    CRISPR

    Tags

    3xFLAG and NLS

    Expression

    Mammalian

    Mutation

    N497A, R661A, Q695A, Q926A

    Promoter

    CBh

    Available Since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pTYB3-human PUM1-HD MUT7-2 (S1079N-E1083Q)-intein-CBD

    Plasmid

    #73299

    Purpose

    Expresses mutant human PUM1-HD

    Depositor

    Traci Hall

    Article

    Cheong et al Proc Natl Acad Sci U S A. 2006 Sep 12;10

    Insert

    human PUM1 Pumilio homology domain (PUM1 Human)
    

    Use

    Tags

    intein

    Expression

    Bacterial

    Mutation

    S1079N-E1083Q

    Promoter

    Available Since

    Feb. 24, 2016

    Availability

    Academic Institutions and Nonprofits only

18. pMIR-Report-RASA1-3'UTR (mut - miR-206 site)

    Plasmid

    #62576

    Purpose

    Translational Luciferase Reporter containing the mutated 3'UTR of RASA1. The miR-206 binding site was mutated.

    Depositor

    Michael Ruppert

    Article

    Sharma et al Mol Cell Biol. 2014 Nov 15;34(22):4143-6

    Insert

    RASA1 (RASA1 Human)
    

    Use

    Luciferase

    Tags

    None

    Expression

    Mutation

    miR-206 binding site mutated (ACATTCCA --> AAC…

    Promoter

    Available Since

    May 28, 2015

    Availability

    Academic Institutions and Nonprofits only

19. siRNA-resistant SigmaR1-mNeonGreen a4mut (I178A L182A L186A V190A)

    Plasmid

    #226577

    Purpose

    Encodes mutant siRNA resistant SigmaR1 protein (substitutions) labeled with mNeonGreen

    Depositor

    Gia Voeltz

    Article

    Sawyer et al Dev Cell. 2024 Jul 2:S1534-5807(24)00382

    Insert

    SigmaR1 (Sigma-1 Receptor) (SIGMAR1 Human)
    

    Use

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    I178A, L182A, L186A, V190A

    Promoter

    Available Since

    Nov. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLY57_TRAC-LHA-pAAV-EFS-CD22BBz-PRODH2-TRAC-RHA(3166mut)

    Plasmid

    #192188

    Purpose

    CD22 CAR AAV vector PRODH2 KI (pLY057)

    Depositor

    Sidi Chen

    Article

    Ye et al Cell Metab. 2022 Apr 5;34(4):595-614.e14

    Insert

    CD22 CAR AAV vector PRODH2 KI (pLY057) (CD22 Synthetic)
    

    Use

    AAV; Mammalian expression

    Tags

    Expression

    Mutation

    NA

    Promoter

    Available Since

    Oct. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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