We narrowed to 27,770 results for: UNK

1. Human Lentiviral sgRNA Library - Unknown Function

   Pooled Library

   #51043

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for gene targets of unknown function.

   Depositor

   David Sabatini, Eric Lander

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

2. HUNK_pCSdest

   Plasmid

   #53809

   Depositor

   Roger Reeves

   Article

   Edie et al G3 (Bethesda). 2018 Jul 2;8(7):2215-2223

   Insert

   HUNK (HUNK Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   SP6 and CMV

   Available since

   March 27, 2018

   Availability

   Industry, Academic Institutions, and Nonprofits

3. CL20_mEGFP_UNK_B4GALNT2

   Plasmid

   #205951

   Purpose

   Express mEGFP-tagged fusion protein, UNK_B4GALNT2 from patient-derived sequence

   Depositor

   Richard Kriwacki

   Article

   Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

   Insert

   UNK_B4GALNT2 (UNK, B4GALNT2 Human)
   

   Use

   Tags

   mEGFP

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Nov. 9, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. UNK_6xZNF_pGEX

   Plasmid

   #215703

   Purpose

   Recombinant expression of UNK with dual-affinity tag

   Depositor

   Daniel Dominguez, Christopher Burge

   Article

   Dominguez et al Mol Cell. 2018 Jun 7;70(5):854-867.e9. d

   Insert

   UNK (UNK Human)
   

   Use

   Tags

   GST and SBP

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   April 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. px458_2A_GFP_sgRNA_UNK_G1

   Plasmid

   #127118

   Depositor

   Thomas Tuschl

   Article

   Meyer et al Mol Cell. 2020 Mar 19;77(6):1193-1205.e5

   Insert

   gRNA UNK (UNK Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   July 25, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pSkunk3-BLA

   Plasmid

   #61531

   Purpose

   Phagemid expressing streptomycin/spectinomycin resistance gene

   Depositor

   Marc Ostermeier

   Article

   Firnberg et al PLoS One. 2012;7(12):e52031. doi: 10.137

   Insert

   aadA
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Promoter

   lacI

   Available since

   Dec. 12, 2014

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. UNK_ZnF1-3_pGEX

   Plasmid

   #219664

   Purpose

   Recombinant expression of UNK ZnF1-3 with dual-affinity tag

   Depositor

   Daniel Dominguez

   Article

   Harris et al Nat Commun. 2024 Sep 27;15(1):8400. doi:

   Insert

   Unkempt Zinc Fingers 1-3
   

   Use

   Tags

   GST and SBP

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Jan. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. UNK_ZnF4-6_pGEX

   Plasmid

   #219665

   Purpose

   Recombinant expression of UNK ZnF4-6 with dual-affinity tag

   Depositor

   Daniel Dominguez

   Article

   Harris et al Nat Commun. 2024 Sep 27;15(1):8400. doi:

   Insert

   Unkempt Zinc Fingers 4-6
   

   Use

   Tags

   GST and SBP

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Jan. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. HUNK gRNA (BRDN0001148239)

   Plasmid

   #75940

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human HUNK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   HUNK (HUNK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. HUNK gRNA (BRDN0001146355)

    Plasmid

    #75939

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human HUNK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    HUNK (HUNK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. HUNK gRNA (BRDN0001145500)

    Plasmid

    #75941

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human HUNK

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    HUNK (HUNK Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. Syn61

    Bacterial Strain

    #174513

    Purpose

    Recoded E. coli strain without TCG, TCA, or TAG codons in all open reading frames. Full sequence - GenBank: CP040347.1

    Depositor

    Jason W Chin

    Article

    Fredens et al Nature. 2019 May;569(7757):514-518. doi:

    Bacterial Resistance

    Streptomycin

    Available since

    Nov. 18, 2021

    Availability

    Academic Institutions and Nonprofits only

13. Syn61Δ3(ev5)

    Bacterial Strain

    #174514

    Purpose

    Recoded E. coli strain without TCG, TCA, or TAG codons and deleted serT, serU and prfA genes. Full sequence - Genbank: CP071799.1

    Depositor

    Jason W Chin

    Article

    Robertson et al Science. 2021 Jun 4;372(6546):1057-1062.

    Bacterial Resistance

    Streptomycin

    Available since

    Nov. 18, 2021

    Availability

    Academic Institutions and Nonprofits only

14. HR700_TP53Exon5mut

    Pooled Library

    #229137

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

15. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

16. HR700_TP53Exon7mut

    Pooled Library

    #229139

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

17. HR700_TP53Exon8mut

    Pooled Library

    #229140

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

18. Mouse sphingolipid metabolism knockout library

    Pooled Library

    #206249

    Purpose

    The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

19. Mouse lipid metabolism knockout library

    Pooled Library

    #206248

    Purpose

    The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

20. Bison sgRNA library

    Pooled Library

    #169942

    Purpose

    The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

    Depositor

    Benjamin Ebert

    Article

    Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

    Use

    Lentiviral

    Available since

    Sept. 9, 2021

    Availability

    Academic Institutions and Nonprofits only