We narrowed to 3,043 results for: NAK

1. pLKO.1-puro-shWRN2

   Plasmid

   #125782

   Purpose

   constitutive expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN2 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLEX307-mFzd9

   Plasmid

   #102877

   Purpose

   Expresses mouse Fzd9 in mammalian cells

   Depositor

   Henry Ho

   Article

   Susman et al Elife. 2017 Sep 8;6. pii: e26509. doi: 1

   Insert

   Frizzled 9 (Fzd9 Mouse)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   A to G substitution at nucleotide 114, G to A sub…

   Promoter

   EF1A

   Available Since

   Dec. 5, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLe6Δ -hLP-mcs/(EGFP-IresPuro-hInt)

   Plasmid

   #64314

   Purpose

   chondrocyte-specific COL11A2 promoter/enhancer lentiviral reporter vector to select iChon cells

   Depositor

   Noriyuki Tsumaki

   Article

   Outani et al PLoS One. 2013 Oct 16;8(10):e77365. doi:

   Inserts

   COL11A2 promoter (COL11A2 Human)
   COL11A2 enhancer (COL11A2 Human)
   

   Use

   Lentiviral

   Tags

   EGFP and IRES-PURO

   Expression

   Mammalian

   Mutation

   N/A

   Available Since

   April 29, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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4. pXPR_BRD003-sgWRN1

   Plasmid

   #125771

   Purpose

   constitutive expression of a guide RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN1 (WRN Human)
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLKO.1-puro-shPSMD2

   Plasmid

   #125779

   Purpose

   constitutive expression of a short-hairpin RNA targeting human PSMD2 (RNAi positive control)

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shPSMD2 (PSMD2 Human)
   

   Use

   RNAi

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pXPR_BRD003-sgWRN2

   Plasmid

   #125772

   Purpose

   constitutive expression of a guide RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN2 (WRN Human)
   

   Use

   CRISPR

   Available Since

   May 29, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pXPR_BRD051-sgCh2-2

   Plasmid

   #125775

   Purpose

   constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control) and S. pyogenes Cas9

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgCh2-2
   

   Use

   CRISPR

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pHAGE2-TetOminiCMV-KS

   Plasmid

   #136617

   Purpose

   Dox-inducible polycistronic reprogramming lentiviral vector expressing mouse Klf4, Sox2

   Depositor

   Hans Schöler

   Article

   Velychko et al Cell Stem Cell. 2019 Oct 30. pii: S1934-

   Insert

   Klf4-IRES-Sox2 (Klf4, Sox2 Mouse)
   

   Use

   Lentiviral

   Expression

   Bacterial

   Promoter

   tetO-miniCMV (dox-inducible)

   Available Since

   March 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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9. pXPR_BRD003-sgWRN3

   Plasmid

   #125773

   Purpose

   constitutive expression of a guide RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN3 (WRN Human)
   

   Use

   CRISPR

   Available Since

   June 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-Ai14-luc

    Plasmid

    #87118

    Purpose

    AAV backbone plasmid including luc-pA knock-in donor and Ai14gRNA for HITI

    Depositor

    Juan Belmonte

    Article

    Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

    Insert

    U6-Ai14sgRNA-Luciferase-nEF-GFPKASH-hGHpA
    

    Use

    AAV, CRISPR, and Luciferase

    Available Since

    March 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. pBOB-Gpr45-161-3xFlag

    Plasmid

    #245993

    Purpose

    Express 3xFlag C-terminal tagged mouse GPR45-N and GPR161-C fusion protein transiently via transfection or stably via lentivirus-mediated infection in mammalian cells.

    Depositor

    Zhao Zhang

    Article

    Xun et al Science. 2025 Jun 5;388(6751):eadp3989.

    Insert

    Gpr45-GPR161161 fusion (Gpr161, Gpr45 Mouse)
    

    Use

    Lentiviral

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    aa 1 to 327 of Gpr45; aa 357 to 558 of Gpr161

    Promoter

    CMV

    Available Since

    Oct. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pBOB-Mrap2-P2A-Mc4r-HA

    Plasmid

    #245991

    Purpose

    Stimultaneously express HA C-terminal tagged mouse MC4R and untagged MRAP2 protein using a P2A linker, transiently via transfection or stably via lentivirus-mediated infection in mammalian cells.

    Depositor

    Zhao Zhang

    Article

    Xun et al Science. 2025 Jun 5;388(6751):eadp3989.

    Insert

    Mrap2 and Mc4r (Mrap2, Mc4r Mouse)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. AAV-FLEX-CAG_G-PTEN

    Plasmid

    #227438

    Purpose

    An AAV backbone for expression of the G-PTEN sensor under the CAG promoter, in a Cre dependent manner.

    Depositor

    Tal Laviv

    Article

    Kagan et al Nat Methods. 2025 Apr;22(4):764-777. doi

    Insert

    G-PTEN sensor (Pten Rat)
    

    Use

    AAV

    Tags

    CD-sREACh and mEGFP

    Expression

    Mammalian

    Mutation

    R14G

    Promoter

    pCAG

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcs2-MTSmut-cox8A(XXXX)-GFP-IRES-mCherry

    Plasmid

    #226104

    Purpose

    Stability reporter construct of the COX8A mitochondrial targeting sequence (MTS) with mutations that impair recognition by SIFI for transient expression in mammalian cells

    Depositor

    Michael Rape

    Article

    Haakonsen et al Nature. 2024 Feb;626(8000):874-880. doi:

    Insert

    COX8A (COX8A Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    encodes only for mitochondrial targeting sequence…

    Available Since

    Oct. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLX304-EZH1-Y727F

    Plasmid

    #203582

    Purpose

    Expresses V5-tagged mutant version of EZH1 partially resistant to JQ-EZ-05 in mammalian cells.

    Depositor

    Abhishek Chakraborty, William Kaelin

    Article

    Chakraborty et al Sci Transl Med. 2017 Jul 12;9(398):eaal5

    Insert

    EZH1 (EZH1 Human)
    

    Use

    Lentiviral

    Tags

    V5-tagged

    Expression

    Mammalian

    Mutation

    changed Tyrosine 727 to Phenylalanine for partial…

    Promoter

    CMV

    Available Since

    Feb. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLX304-EZH1-dPSET

    Plasmid

    #203586

    Purpose

    Expresses V5-tagged mutant version of EZH1 with deletion of aa 744-747 and partially resistant to JQ-EZ-05 in mammalian cells.

    Depositor

    Abhishek Chakraborty, William Kaelin

    Article

    Chakraborty et al Sci Transl Med. 2017 Jul 12;9(398):eaal5

    Insert

    EZH1 (EZH1 Human)
    

    Use

    Lentiviral

    Tags

    V5-tagged

    Expression

    Mammalian

    Mutation

    deletion of aa 744-747 and partial resistance to …

    Promoter

    CMV

    Available Since

    Feb. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pLX304-EZH1-D745N

    Plasmid

    #203585

    Purpose

    Expresses V5-tagged mutant version of EZH1 partially resistant to JQ-EZ-05 in mammalian cells.

    Depositor

    Abhishek Chakraborty, William Kaelin

    Article

    Chakraborty et al Sci Transl Med. 2017 Jul 12;9(398):eaal5

    Insert

    EZH1 (EZH1 Human)
    

    Use

    Lentiviral

    Tags

    V5-tagged

    Expression

    Mammalian

    Mutation

    changed Aspartic Acid 745 to Asparagine for parti…

    Promoter

    CMV

    Available Since

    Feb. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pU6-gRNA(SFTPCI73Tcorr)-SpCas9(BB)-2A-GFP

    Plasmid

    #187647

    Purpose

    Encodes gRNA to correct the SFTPC I73T mutation

    Depositor

    Darrell Kotton

    Article

    Alysandratos et al Cell Rep. 2021 Aug 31;36(9):109636. doi:

    Insert

    I73T gRNA
    

    Use

    CRISPR

    Available Since

    Aug. 31, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pnCS_DSep2_Peanut-TEV-Strep

    Plasmid

    #174495

    Purpose

    bacterial co-expression of Drosophila Sep2 and of Drosophila Peanut

    Depositor

    Manos Mavrakis

    Article

    Iv et al J Cell Sci. 2021 Jul 8. pii: 270842. doi

    Inserts

    Sep2 (Sep2 Fly)
    peanut (pnut Fly)
    

    Tags

    TEV-Strep

    Expression

    Bacterial

    Available Since

    Sept. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLKO.1-puro-shRPS6

    Plasmid

    #125780

    Purpose

    constitutive expression of a short-hairpin RNA targeting human RPS6 (RNAi positive control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    shRPS6 (RPS6 Human)
    

    Use

    RNAi

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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