We narrowed to 5,364 results for: pAAV

1. pC131: pAAV.CMV-CasRx-VEGFA sgRNA array

   Plasmid

   #203444

   Purpose

   Plasmid expressing active RfxCas13d with an array of three VEGFA mRNA targeting gRNAs

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA array
   RfxCas13d
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pM150: pAAV.CMV-Cas13e-VEGFA sgRNA array

   Plasmid

   #203448

   Purpose

   Plasmid expressing active Cas13e with an array of three VEGFA mRNA targeting gRNAs

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA array
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pM156: pAAV.CMV-Cas13e (GenScript CO)-VEGFA sgRNA

   Plasmid

   #203452

   Purpose

   Plasmid expressing active and codon optimised Cas13e with VEGFA gRNA

   Depositor

   Guei-Sheung Liu

   Article

   Kumar et al Proc Natl Acad Sci U S A. 2024 Nov 5;121

   Inserts

   U6-VEGFA sgRNA
   Cas13e
   

   Use

   AAV

   Tags

   HA and NLS

   Expression

   Mammalian

   Promoter

   CMV and U6

   Available Since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pAAV-U6-sgRev-erba-hSyn-mCherry-KASH

   Plasmid

   #223226

   Purpose

   guideRNA targeting the mouse Rev-erb alpha (Nr1d1)

   Depositor

   Kyungjin Kim

   Article

   Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

   Insert

   Nr1d1 (Nr1d1 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. AiP1921 - pAAV-AiE2447m-SYFP2-WPRE-BGHpA

   Plasmid

   #214581

   Purpose

   AiE2447m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

   Depositor

   Bosiljka Tasic, Allen Institute for Brain Science

   Article

   Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

   Insert

   SYFP2
   

   Use

   AAV

   Promoter

   minBG

   Available Since

   June 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-hSyn-DIO-NES-jRGECO1a-WPRE

   Plasmid

   #216276

   Purpose

   AAV vector with hSynapsin promoter and DIO Lox sites for Cre-On expression of red fluorescent calcium indicator jRGECO1a

   Depositor

   Guohong Cui

   Article

   Meng et al Neuron. 2018 May 16;98(4):707-717.e4. do

   Insert

   NES-jRGECO1a
   

   Use

   AAV and Cre/Lox

   Tags

   6XHIS and Xpress

   Promoter

   human synapsin 1 (hSyn)

   Available Since

   May 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-CMVd1-NLS-GAL4-iLight-VP16

   Plasmid

   #219549

   Purpose

   NLS-Gal4(1-65)-iLight-VP16 construc expression in mammalian cells. pAAV vector.

   Depositor

   Vladislav Verkhusha

   Article

   Baloban et al Protein Sci. 2024 May;33(5):e4993. doi:

   Insert

   NLS-Gal4(1-65)-iLight-VP16
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   CMVd1

   Available Since

   May 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-hSyn-frt-DIO-hM3D(Gq)-mCherry

   Plasmid

   #217397

   Purpose

   Expresses the hM3D(Gq) excitatory DREADD fused to mCherry, in a Cre-ON and FLP-OFF dependent manner, under the control of hSyn promoter

   Depositor

   Oscar Marin

   Insert

   hM3D(Gq)-mCherry
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   human Synapsin 1

   Available Since

   May 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-hSyn-frt-DIO-hM4D(Gi)-mCherry

   Plasmid

   #217398

   Purpose

   Expresses the hM4D(Gi) inhibitory DREADD fused to mCherry, in a Cre-ON and FLP-OFF dependent manner, under the control of hSyn promoter

   Depositor

   Oscar Marin

   Insert

   hM4D(Gi)-mCherry
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   human Synapsin 1

   Available Since

   May 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-Syn1-DIO-Snca (human A53T)

    Plasmid

    #214201

    Purpose

    For Cre-dependent expression of alpha synuclein (human gene containing A53T mutation)

    Depositor

    Thomas Hnasko

    Article

    Steinkellner et al Brain. 2022 Apr 29;145(3):879-886. doi:

    Insert

    Snca (A53T) (SNCA Human)
    

    Use

    AAV and Cre/Lox

    Expression

    Mammalian

    Mutation

    A53T

    Available Since

    March 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pOTTC1992 - pAAV EF1a CoV2 Orf3a-2xStrep

    Plasmid

    #213542

    Purpose

    AAV viral vector packaging plasmid that expresses CoV2

    Depositor

    Christopher Richie, Brandon Harvey

    Insert

    CoV2 Orf3a-2xStrep (ORF3a Human, Severe acute respiratory syndrome coronavirus 2)
    

    Use

    AAV

    Promoter

    EF1a

    Available Since

    Feb. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pOTTC1993 - pAAV EF1a CoV2 protE-2xStrep

    Plasmid

    #213543

    Purpose

    AAV viral vector packaging plasmid that expresses CoV2

    Depositor

    Christopher Richie, Brandon Harvey

    Insert

    CoV2 protE-2xStrep (E Human, Severe acute respiratory syndrome coronavirus 2)
    

    Use

    AAV

    Promoter

    EF1a

    Available Since

    Feb. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAAV-hSyn-DIO-myr-rsEGFP2- LDLR

    Plasmid

    #213399

    Purpose

    double floxed, myristoylation site (myr) and LDLR, fused to reversibly switchable EGFP rsEGFP2

    Depositor

    Katrin Willig

    Article

    Willig et al Cell Rep. 2021 Jun 1;35(9):109192. doi:

    Insert

    rsEGFP2
    

    Use

    AAV

    Tags

    C-terminal (Ct) cytoplasmic domains of low densit…

    Expression

    Mammalian

    Available Since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-EFS-TadA8e-Sauri-U6-Lmna sgRNA

    Plasmid

    #206979

    Purpose

    Expresses SauriABE8e by EFS promoter and sgRNA targeting murine Lmna c.1621T mutation by U6 promoter

    Depositor

    Yuxuan Guo

    Article

    Yang et al J Cell Mol Med. 2024 Feb;28(4):e18145. d

    Insert

    Lmna sgRNA
    

    Use

    AAV; Adenine base editor

    Promoter

    U6

    Available Since

    Feb. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-cFOS-FRB-VP16-P2A-EGFP

    Plasmid

    #210510

    Purpose

    expresses cFOS-FRB-VP16 and EGFP component in rat hippocampal neuron cells

    Depositor

    Dongmin Lee

    Article

    Cui et al Nat Chem Biol. 2024 Mar;20(3):353-364. d

    Insert

    FRB-VP16-P2A-EGFP
    

    Use

    AAV

    Expression

    Mammalian

    Promoter

    cFos

    Available Since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV-CMV-FLEXfrt-SaCas9-U6-sgNtsr1(guide_2)

    Plasmid

    #205417

    Purpose

    Mutagenesis of Ntsr1, second guide

    Depositor

    Larry Zweifel

    Insert

    Ntsr1 (Ntsr1 Mouse)
    

    Use

    AAV and CRISPR

    Promoter

    U6

    Available Since

    Sept. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV-CAG-EGFP barcode-9-SV40 polyA

    Plasmid

    #190873

    Purpose

    For barcoded retrograde labeling

    Depositor

    Yuejun Chen

    Article

    Xu et al Elife. 2024 Feb 23;13:e85419. doi: 10.75

    Insert

    EGFP-barcode9
    

    Use

    AAV

    Mutation

    WT

    Available Since

    Aug. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pOTTC1663 - pAAV SYN1 mGas6-Myc-DDK

    Plasmid

    #202540

    Purpose

    An adeno-associated viral vector expressing murine Gas6 fused Myc and DDK epitopes from a synapsin promoter

    Depositor

    Christopher Richie

    Article

    Owlett et al J Neuroinflammation. 2022 Feb 7;19(1):38

    Insert

    Gas6 (Gas6 Mouse)
    

    Use

    AAV

    Tags

    Myc-DDK

    Promoter

    SYN1

    Available Since

    June 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV2ss-EFS-GFP-synPolyA-U6-sgHTT1-U6-sgCas9

    Plasmid

    #190903

    Purpose

    AAV-KamiCas9 vector expressing expressing thew GFP reporter gene and sgHTT and sgCas9

    Depositor

    Nicole Déglon

    Article

    Duarte et al Mol Ther Methods Clin Dev. 2023 Mar 27;2

    Insert

    GFP, sgHTT and sgCas9 (HTT Human)
    

    Use

    AAV and CRISPR

    Promoter

    EFS and U6

    Available Since

    March 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-CAGGS-Flex/3'USS(103)-GFP

    Plasmid

    #197890

    Purpose

    Can be used to generate AAV virus that will express GFP in the presence of Cre including the shortage of a unilateral spacer sequence(USS)

    Depositor

    Kazuto Kobayashi

    Article

    Matsushita et al Cell Rep Methods. 2023 Jan 18;3(2):10039

    Insert

    GFP
    

    Use

    AAV

    Mutation

    N/A

    Promoter

    CAG

    Available Since

    March 15, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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