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pUC-ChREBPα

Plasmid

#211754

Purpose

Cloning vector for the expression of mouse ChREBPα

Depositor

Russell Goodman

Article

Singh et al Cell Metab. 2024 Jan 2;36(1):144-158.e7.

Insert

MLXIPL (Mlxipl Mouse)

Use

Cloning vector

Available Since

Feb. 2, 2024

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRv2-sgFXN-1

Plasmid

#246017

Purpose

All-in-one CRISPRko plasmid containing Cas9 and guide RNA targeting FXN

Depositor

Vamsi Mootha

Article

Ast et al Cell. 2019 May 30;177(6):1507-1521.e16.

Insert

Frataxin (FXN Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

Oct. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRv2-sgFXN-2

Plasmid

#246018

Purpose

All-in-one CRISPRko plasmid containing Cas9 and guide RNA targeting FXN

Depositor

Vamsi Mootha

Article

Ast et al Cell. 2019 May 30;177(6):1507-1521.e16.

Insert

Frataxin (FXN Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Available Since

Oct. 2, 2025

Availability

Academic Institutions and Nonprofits only

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pDONR223_PIK3CD_WT

Plasmid

#82222

Purpose

Gateway Donor vector containing PIK3CD , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

PIK3CD (PIK3CD Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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TCF7L2_pLX307

Plasmid

#98373

Purpose

Lentiviral expression of TCF7L2

Depositor

William Hahn, Sefi Rosenbluh

Article

Rosenbluh et al Cell Syst. 2016 Sep 28;3(3):302-316.e4.

Insert

TCF7L2 (TCF7L2 Human)

Use

Lentiviral

Tags

V5

Expression

Mammalian

Mutation

Isoform X25

Promoter

E1Fa

Available Since

Aug. 24, 2017

Availability

Academic Institutions and Nonprofits only

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pLenti-CRISPRv2-sgIl1r1_#2-hygro

Plasmid

#231990

Purpose

Knockout mouse Il1r1

Depositor

Brian Ruffell

Article

Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

Insert

sgRNA with Cas9 and hygromycin resistance (Il1r1 Mouse)

Use

CRISPR and Lentiviral

Available Since

Feb. 19, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1 Flag Cl-sensitive YFP hNKCC1 WT (NT13)

Plasmid

#49060

Purpose

Expresses human NKCC1 with an N-terminal 3xFlag-YFP-(chloride-sensing) tag in mammalian cells. cDNA is synthetic, containing convenient restriction sites. Native hNKCC1 amino acid sequence

Depositor

Biff Forbush

Article

Somasekharan et al PLoS One. 2013 Dec 5;8(12):e82060. doi:

Insert

human NKCC1 (synthetic) (SLC12A2 Human, Synthetic)

Tags

3x Flag and YFP (chloride-sensitive)

Expression

Mammalian

Mutation

Cl-sensitive YFP (EYFP/ V163S A206K) in hNKCC1 in…

Promoter

CMV

Available Since

Nov. 7, 2013

Availability

Academic Institutions and Nonprofits only

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pDONR223_PPP2R1A_WT

Plasmid

#81760

Purpose

Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

PPP2R1A (PPP2R1A Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_CYP3A5_WT

Plasmid

#81823

Purpose

Gateway Donor vector containing CYP3A5 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

CYP3A5 (CYP3A5 Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_SPOP_p.F133S

Plasmid

#81637

Purpose

Gateway Donor vector containing SPOP, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

SPOP (SPOP Human)

Use

Gateway entry vector

Mutation

F133S

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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ACO2_pLX307

Plasmid

#98312

Purpose

Lentiviral expression of ACO2

Depositor

William Hahn, Sefi Rosenbluh

Article

Rosenbluh et al Cell Syst. 2016 Sep 28;3(3):302-316.e4.

Insert

ACO2 (ACO2 Human)

Use

Lentiviral

Tags

V5

Expression

Mammalian

Promoter

E1Fa

Available Since

Aug. 23, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_TBL1XR1_WT

Plasmid

#82059

Purpose

Gateway Donor vector containing TBL1XR1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

TBL1XR1 (TBL1XR1 Human)

Use

Gateway entry vector

Mutation

L512P

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_KIR3DL2_WT

Plasmid

#81773

Purpose

Gateway Donor vector containing KIR3DL2 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

KIR3DL2 (KIR3DL2 Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pSecTaq2-hProS-Myc-6xHis

Plasmid

#226524

Purpose

Expresses TAM Receptor Ligand human PROS1

Depositor

Raymond Birge, Sergei Kotenko

Article

Geng et al Front Immunol. 2017 Nov 10;8:1521. doi:

Insert

Human PROS1 (PROS1 Human)

Expression

Mammalian

Promoter

CMV

Available Since

Nov. 26, 2024

Availability

Academic Institutions and Nonprofits only

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pDONR223_SERPINB4_WT

Plasmid

#81766

Purpose

Gateway Donor vector containing SERPINB4 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

SERPINB4 (SERPINB4 Human)

Use

Gateway entry vector

Mutation

WT

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_SPOP_p.W131G

Plasmid

#81632

Purpose

Gateway Donor vector containing SPOP , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

SPOP (SPOP Human)

Use

Gateway entry vector

Mutation

W131G

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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CCNT1_pLX307

Plasmid

#98328

Purpose

Lentiviral expression of CCNT1

Depositor

William Hahn, Sefi Rosenbluh

Article

Rosenbluh et al Cell Syst. 2016 Sep 28;3(3):302-316.e4.

Insert

CCNT1 (CCNT1 Human)

Use

Lentiviral

Tags

V5

Expression

Mammalian

Mutation

H519R, S566P, and P712S

Promoter

E1Fa

Available Since

Aug. 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_S100A13_WT_V5

Plasmid

#82975

Purpose

Gateway Donor vector containing S100A13, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, Matthew Meyerson, David Root

Article

Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

Insert

S100A13 (S100A13 Human)

Use

Gateway entry vector

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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CSNK1A1_pLX307

Plasmid

#98326

Purpose

Lentiviral expression of CSNK1A1

Depositor

William Hahn, Sefi Rosenbluh

Article

Rosenbluh et al Cell Syst. 2016 Sep 28;3(3):302-316.e4.

Insert

CSNK1A1 (CSNK1A1 Human)

Use

Lentiviral

Tags

V5

Expression

Mammalian

Promoter

E1Fa

Available Since

Aug. 10, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_SPOP_p.F102C

Plasmid

#81642

Purpose

Gateway Donor vector containing SPOP, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

SPOP (SPOP Human)

Use

Gateway entry vector

Mutation

F102C

Promoter

None

Available Since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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