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pGL4-CMV-myc-XPO1

Plasmid

#242469

Purpose

Expresses human XPO1 protein with an N-terminal cMyc tag.

Depositor

Dirk Daelemans

Publication

Wing et al Nat Chem Biol. 2025 Dec;21(12):2002-2013

Insert

XPO1 (XPO1 Human)

Tags

cMyc

Expression

Mammalian

Promoter

CMV

Available since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pGL4-CMV-FLAG-XPO1

Plasmid

#242459

Purpose

Expresses human XPO1 with an N-terminal FLAG tag for pull-down assays.

Depositor

Dirk Daelemans

Publication

Wing et al Nat Chem Biol. 2025 Dec;21(12):2002-2013

Insert

XPO1 (XPO1 Human)

Tags

FLAG

Expression

Mammalian

Promoter

CMV

Available since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pDONR223_XPO1_p.E571K

Plasmid

#81554

Purpose

Gateway Donor vector containing XPO1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Publication

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

XPO1 (XPO1 Human)

Use

Gateway Cloning

Mutation

E571K

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pGL4-CMV-myc-XPO1_V518E_F561H

Plasmid

#242470

Purpose

Expresses human XPO1 protein with an N-terminal cMyc tag. The V518E_5561H mutations disrupt ASB8 binding.

Depositor

Dirk Daelemans

Publication

Wing et al Nat Chem Biol. 2025 Dec;21(12):2002-2013

Insert

XPO1 (XPO1 Human)

Tags

cMyc

Expression

Mammalian

Mutation

V518E - F561H

Promoter

CMV

Available since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pGL4-CMV-myc-XPO1_H10-11

Plasmid

#242471

Purpose

Expresses human XPO1 protein with an N-terminal cMyc tag. The H10-11 mutations disrupt ASB8 binding.

Depositor

Dirk Daelemans

Publication

Wing et al Nat Chem Biol. 2025 Dec;21(12):2002-2013

Insert

XPO1 (XPO1 Human)

Tags

cMyc

Expression

Mammalian

Mutation

XPO1 H10-11 = E478A - H481A - V484G - N485G - T48…

Promoter

CMV

Available since

Nov. 24, 2025

Availability

Academic Institutions and Nonprofits only

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pDONR223_XPO1_p.E571A

Plasmid

#81600

Purpose

Gateway Donor vector containing XPO1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Publication

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

XPO1 (XPO1 Human)

Use

Gateway Cloning

Mutation

E571A

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_XPO1_p.R553C

Plasmid

#81555

Purpose

Gateway Donor vector containing XPO1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Publication

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

XPO1 (XPO1 Human)

Use

Gateway Cloning

Mutation

R553C

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pHR_Gal4UAS_Pembrolizumab_heavychain_T2A_ Pembrolizumab_lightchain_PGK_mCherry

Plasmid

#85434

Purpose

Lentiviral vector for Gal4 inducible leucinezipper Pembrolizumab and constitutive mCherry expression

Depositor

Wendell Lim

Publication

Roybal et al Cell. 2016 Oct 6;167(2):419-432.e16. doi

Insert

Pembrolizumab

Use

Lentiviral

Available since

Sept. 19, 2017

Availability

Academic Institutions and Nonprofits only

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pNLF1-C_XPO1:1-1071

Plasmid

#211088

Purpose

Mammalian expression of full-length human XPO1. C-terminal NanoLuc luciferase tag.

Depositor

Cheryl Arrowsmith

Publication

Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

XPO1:M1-D1071 (XPO1 Human)

Tags

NanoLuc luciferase

Expression

Mammalian

Mutation

wild type

Promoter

CMV

Available since

March 19, 2024

Availability

Academic Institutions and Nonprofits only

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pDONR223_XPO1_WT

Plasmid

#81812

Purpose

Gateway Donor vector containing XPO1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Publication

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

XPO1 (XPO1 Human)

Use

Gateway Cloning

Mutation

WT

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pAPM-miR30-XPO1-ts1

Plasmid

#174286

Purpose

XPO1 knockdown

Depositor

Jeremy Luban

Publication

Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

Insert

XPO1 shRNA (XPO1 Human)

Use

Lentiviral and RNAi

Promoter

SFFV

Available since

Aug. 27, 2024

Availability

Academic Institutions and Nonprofits only

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pAPM-miR30-XPO1-ts2

Plasmid

#174287

Purpose

XPO1 knockdown

Depositor

Jeremy Luban

Publication

Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

Insert

XPO1 shRNA (XPO1 Human)

Use

Lentiviral and RNAi

Promoter

SFFV

Available since

Aug. 27, 2024

Availability

Academic Institutions and Nonprofits only

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pAPM-miR30-XPO1-ts3

Plasmid

#174288

Purpose

XPO1 knockdown

Depositor

Jeremy Luban

Publication

Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

Insert

XPO1 shRNA (XPO1 Human)

Use

Lentiviral and RNAi

Promoter

SFFV

Available since

Aug. 27, 2024

Availability

Academic Institutions and Nonprofits only

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pGEMHE-membrane-mEGFP

Plasmid

#105526

Purpose

T7 promotor drives in vitro mRNA transcription of a mEGFP-tagged membrane reporter

Depositor

Melina Schuh

Publication

Clift et al Cell. 2017 Nov 13. pii: S0092-8674(17)31

Insert

GNAI2 (GNAI2 Human)

Use

In vitro transcription

Tags

mEGFP

Mutation

fragment encoding the plasma membrane targeting s…

Promoter

T7

Available since

March 7, 2018

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pv6_MCPH1-TandemBRCT

Plasmid

#250354

Purpose

Expresses tandem BRCT domain from MCPH1 fused to eGFP. Can be used to detect yH2AX at DNA damage sites.

Depositor

Tuncay Baubec

Publication

da Silva et al Nat Commun. 2025 Nov 20;16(1):10127. doi

Insert

MCPH1 tandem BRCT

Tags

NLS, eGFP and biotintag, TEV cleavage

Expression

Mammalian

Promoter

CAGGS

Available since

Feb. 10, 2026

Availability

Academic Institutions and Nonprofits only

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pCS-membrane-ceruleanFP

Plasmid

#53749

Purpose

Contains membrane localized cerulean fluorescent protein in pCS expression vector.

Depositor

Sean Megason

Publication

Megason et al Methods Mol Biol. 2009;546:317-32. doi:

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

2x membrane linker

Tags

Cerulean

Expression

Mammalian

Promoter

simian CMV IE94

Available since

June 10, 2014

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles

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Plasma membrane-targeted optoPLD

Plasmid

#140114

Purpose

Encodes CRY2-mCherry-PLD-P2A-CIBN-CAAX for mammalian expression

Depositor

Jeremy Baskin

Publication

Tei et al J Cell Biol. 2020 Mar 2;219(3). pii: 133

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

Phospholipase D

Tags

CAAX, CIBN, CRY2, P2A, and mCherry

Expression

Mammalian

Available since

March 24, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles

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pGEMT-mMyh3CDS

Plasmid

#192843

Purpose

Plasmid to produce ISH probe for mMyh3 gene with CDS sequence

Depositor

Masafumi Inui

Publication

Tanji et al Dev Growth Differ. 2022 Dec 14. doi: 10.

Insert

myosin heavy chain 3 (Myh3 Mouse)

Available since

Dec. 5, 2024

Availability

Academic Institutions and Nonprofits only

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pGEMT-mMyh3UTR

Plasmid

#192844

Purpose

Plasmid to produce ISH probe for mMyh3 gene with UTR sequence

Depositor

Masafumi Inui

Publication

Tanji et al Dev Growth Differ. 2022 Dec 14. doi: 10.

Insert

myosin heavy chain 3 (Myh3 Mouse)

Available since

Dec. 5, 2024

Availability

Academic Institutions and Nonprofits only

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gRNA_Cloning Vector

Plasmid

#41824

Purpose

An empty gRNA expression vector, used to create a gRNA to a specific sequence.

Depositor

George Church

Publication

Mali et al Science. 2013 Feb 15;339(6121):823-6. do

Type

Empty backbone

Use

CRISPR

Tags

AflII site for Gibson Assembly

Expression

Mammalian

Available since

Jan. 11, 2013

Availability

Academic Institutions and Nonprofits only

Cited by

375 Articles

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