We narrowed to 4,407 results for: crispr c plasmids

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Lenti-sgRNA-Cre-GpNLuc-sgmZBP1#1

Plasmid

#208387

Purpose

Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine ZBP1#1 gene.

Depositor

Gaorav Gupta

Publication

Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

Insert

sgZBP1 (Zbp1 Mouse)

Use

Lentiviral and Luciferase

Expression

Mammalian

Mutation

WT

Available since

Jan. 11, 2024

Availability

Academic Institutions and Nonprofits only

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Lenti-sgRNA-Cre-GpNLuc-sgmZBP1#2

Plasmid

#208388

Purpose

Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine ZBP1#2 gene.

Depositor

Gaorav Gupta

Publication

Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

Insert

sgZBP1 (Zbp1 Mouse)

Use

Lentiviral and Luciferase

Expression

Mammalian

Mutation

WT

Available since

Jan. 11, 2024

Availability

Academic Institutions and Nonprofits only

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pEF1a-CRY2PHR-SID4X

Plasmid

#63663

Purpose

AAV expression of CRYS2PHR-SID4X

Depositor

Dong Kong

Publication

Chen et al Theranostics. 2018 Aug 7;8(16):4447-4461

Insert

SID4X-CYR2PHR

Use

AAV

Expression

Mammalian

Promoter

EF1alpha

Available since

Sept. 13, 2018

Availability

Academic Institutions and Nonprofits only

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pPB_TRE3G_scFV-sfGFP-Dot1LCD-CatMut

Plasmid

#235591

Purpose

Dox-inducible expression of control catalytic-mutant Dot1l CD fused with scFV

Depositor

Jamie Hackett

Publication

Policarpi et al Nat Genet. 2024 Jun;56(6):1168-1180. doi

Insert

Dot1l (Dot1l Mouse)

Use

CRISPR

Mutation

GS163-164RC

Available since

April 30, 2025

Availability

Academic Institutions and Nonprofits only

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pPB_TRE3G_scFV-sfGFP-Setd2CD-CatMut

Plasmid

#235588

Purpose

Dox-inducible expression of control catalytic-mutant Setd2 CD fused with scFV

Depositor

Jamie Hackett

Publication

Policarpi et al Nat Genet. 2024 Jun;56(6):1168-1180. doi

Insert

Setd2 (Setd2 Mouse)

Use

CRISPR

Mutation

R1599C

Available since

April 30, 2025

Availability

Academic Institutions and Nonprofits only

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pX601‐mhCMV‐miniABEmax‐N3‐ E53ogRNA

Plasmid

#187064

Purpose

Npu Split N-terminal half of ABEmaxNGA with gRNA targeting mdx4cv nonsense mutation

Depositor

Renzhi Han

Publication

Xu et al Nat Commun. 2021 Jun 17;12(1):3719. doi:

Insert

miniABEmax-Npu

Use

AAV and CRISPR

Expression

Mammalian

Promoter

mhCMV

Available since

Aug. 8, 2022

Availability

Academic Institutions and Nonprofits only

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pJET-42-DExCon-antiGFPnanobody-mCherry-R11a

Plasmid

#179902

Purpose

Donor with homologous arms for Rab11a to knock in DExCon-antiGFPnanobody-mCherry module

Depositor

Patrick Caswell

Publication

Gemperle et al Elife. 2022 Jun 16;11. pii: 76651. doi:

Insert

RAB11A, member RAS oncogene family (RAB11A Human)

Use

CRISPR; Donor for homologous based knock in

Tags

antiGFPnanobody-mCherry

Expression

Bacterial and Mammalian

Promoter

TRE3GS

Available since

May 31, 2022

Availability

Academic Institutions and Nonprofits only

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Little Prince-enOsCas12f1

Plasmid

#251232

Purpose

Drug inducible gene editing system based on enOsCas12f1 (Little Prince)

Depositor

Yu Wang

Publication

Zhang et al Sci Transl Med. 2026 May 27;18(851):eadx

Insert

H1-TetO-enOsCas12f1 sgRNA scaffold; Core EF1α-opTtetR; enOsCas12f1; NES; StaPLs-TI; 3×BPNLS; GFP

Use

AAV and CRISPR

Expression

Mammalian

Available since

July 2, 2026

Availability

Academic Institutions and Nonprofits only

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Little Prince (TnpB)

Plasmid

#251233

Purpose

Drug inducible gene editing system based on TnpB (Little Prince)

Depositor

Yu Wang

Publication

Zhang et al Sci Transl Med. 2026 May 27;18(851):eadx

Insert

H1-TetO-TnpB ωRNA* scaffold; Core EF1α-opTtetR; TnpB; NES; StaPLs-TI; 3×BPNLS; GFP

Use

AAV and CRISPR

Expression

Mammalian

Available since

July 2, 2026

Availability

Academic Institutions and Nonprofits only

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Little Prince (enIscB)

Plasmid

#251234

Purpose

Drug inducible gene editing system based on enIscB (Little Prince)

Depositor

Yu Wang

Publication

Zhang et al Sci Transl Med. 2026 May 27;18(851):eadx

Insert

H1-TetO-enIscB ωRNA* scaffold; Core EF1α-opTtetR; enIscB; NES; StaPLs-TI; 3×BPNLS; GFP

Use

AAV and CRISPR

Expression

Mammalian

Available since

July 2, 2026

Availability

Academic Institutions and Nonprofits only

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pML107-LUG1

Plasmid

#226265

Purpose

Plasmid expressing Cas9 and gRNA TCTTCAAGTTACTCCAAGAG which targets the LUG1 gene

Depositor

Jolanda Van Leeuwen

Publication

Paltenghi et al G3 (Bethesda). 2025 Mar 3:jkaf047. doi:

Insert

LUG1 gRNA (YLR352W Budding Yeast)

Use

CRISPR

Expression

Yeast

Available since

Oct. 28, 2024

Availability

Academic Institutions and Nonprofits only

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pML104-LEU2-2

Plasmid

#226263

Purpose

Plasmid expressing Cas9 and gRNA GGTAGTGTTAGACCTGAACA which targets the LEU2 gene

Depositor

Jolanda Van Leeuwen

Publication

Paltenghi et al G3 (Bethesda). 2025 Mar 3:jkaf047. doi:

Insert

LEU2 gRNA (LEU2 Budding Yeast)

Use

CRISPR

Expression

Yeast

Available since

Oct. 28, 2024

Availability

Academic Institutions and Nonprofits only

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pRS423-TyrSgH

Plasmid

#163973

Purpose

Helper plasmid for cloning gRNAs under the control of the tRNA(Tyr) promoter

Depositor

Jiazhang Lian

Publication

Dong et al ACS Synth Biol. 2020 Sep 18;9(9):2252-22

Type

Empty backbone

Use

Synthetic Biology

Expression

Yeast

Available since

Feb. 1, 2021

Availability

Academic Institutions and Nonprofits only

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pRS423-SgH

Plasmid

#163972

Purpose

Helper plasmid for cloning gRNAs under the control of the SNR52 promoter.

Depositor

Jiazhang Lian

Publication

Dong et al ACS Synth Biol. 2020 Sep 18;9(9):2252-22

Type

Empty backbone

Use

Synthetic Biology

Expression

Yeast

Available since

Feb. 1, 2021

Availability

Academic Institutions and Nonprofits only

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pOT_4 - lenti-EFS-FMC6.3-BBz-2A-puro-2A-LTBR

Plasmid

#181973

Purpose

Expresses anti-CD19 CAR (with 4-1BB signaling domain) linked to puromycin resistance via P2A and to human LTBR via T2A for lentiviral delivery.

Depositor

Neville Sanjana

Publication

Legut et al Nature. 2022 Mar;603(7902):728-735. doi:

Insert

FMC6.3-BBz CAR; LTBR (LTBR Synthetic, Human)

Use

Lentiviral

Available since

April 25, 2022

Availability

Academic Institutions and Nonprofits only

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pTarget-TTC

Plasmid

#246930

Purpose

for E.coli plasmid interference and PAM depletion assays

Depositor

Caixia Gao

Publication

Jin et al Cell. 2025 Sep 29:S0092-8674(25)01035-9.

Insert

TTC PAM and GFP-T1 target

Use

Unspecified

Available since

Nov. 18, 2025

Availability

Academic Institutions and Nonprofits only

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pLenti_CMV_Puro_SFB_GNB1L_WD 7 deletion

Plasmid

#224388

Purpose

Lenti plasmid for generating GNB1L _WD 7 domain depleted expressing stable cell lines

Depositor

Junjie Chen

Publication

Huang et al Mol Cell. 2023 Aug 3;83(15):2810-2828.e6

Insert

GNB1L (GNB1L Human)

Expression

Bacterial and Mammalian

Mutation

WD 7 domain deleted (aa 286-323)

Available since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

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pLenti_CMV_Puro_SFB_GNB1L_WD 6 deletion

Plasmid

#224387

Purpose

Lenti plasmid for generating GNB1L _WD 6 domain depleted expressing stable cell lines

Depositor

Junjie Chen

Publication

Huang et al Mol Cell. 2023 Aug 3;83(15):2810-2828.e6

Insert

GNB1L (GNB1L Human)

Expression

Bacterial and Mammalian

Mutation

WD 6 domain deleted (aa 242-282)

Available since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

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pLenti_CMV_Puro_SFB_GNB1L_WD 4 deletion

Plasmid

#224385

Purpose

Lenti plasmid for generating GNB1L _WD 4 domain depleted expressing stable cell lines

Depositor

Junjie Chen

Publication

Huang et al Mol Cell. 2023 Aug 3;83(15):2810-2828.e6

Insert

GNB1L (GNB1L Human)

Expression

Bacterial and Mammalian

Mutation

WD 4 domain deleted (aa 153-195)

Available since

Oct. 9, 2024

Availability

Academic Institutions and Nonprofits only

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AAT_g1 gRNA

Plasmid

#86005

Purpose

plasmid vector encoding for U6-driven AAT_g1 gRNA

Depositor

Tobias Cantz

Publication

Eggenschwiler et al Sci Rep. 2016 Dec 2;6:38198. doi: 10.103

Insert

pU6-AAT_g1 sgRNA

Use

CRISPR

Expression

Mammalian

Promoter

pU6

Available since

Feb. 1, 2017

Availability

Academic Institutions and Nonprofits only

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