We narrowed to 4,523 results for: GCA;

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pOTTC1270 - pAAV Rosa26 gRNA A+B EF1a EGFP

Plasmid

#113156

Purpose

An AAV vector that expresses guide RNAs targeting rat Rosa26 and expresses EGFP reporter

Depositor

Brandon Harvey

Article

Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

Insert

Two gRNAs for rat Rosa26

Use

AAV and CRISPR

Expression

Mammalian

Promoter

mU6 and hU6

Available Since

March 7, 2019

Availability

Academic Institutions and Nonprofits only

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TET-pLKO.1 PURO shGDF11 #1

Plasmid

#83083

Purpose

Lentiviral shRNA vector for inducible knockdown of human GDF11 (cross reacts with mouse Gdf11)

Depositor

Kevin Janes

Article

Bajikar et al Dev Cell. 2017 Nov 20;43(4):418-435.e13.

Insert

shGDF11 (GDF11, Gdf11 Mouse, Human)

Use

Lentiviral

Expression

Mammalian

Available Since

Feb. 28, 2019

Availability

Academic Institutions and Nonprofits only
TAF1 gRNA (BRDN0001147230)

Plasmid

#77869

Purpose

3rd generation lentiviral gRNA plasmid targeting human TAF1

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TAF1 (TAF1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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sgEGFR(B)

Plasmid

#85565

Purpose

Expresses sgRNA targeting human EGFR around codon T790

Depositor

Luca Grumolato

Article

Guernet et al Mol Cell. 2016 Aug 4;63(3):526-38. doi:

Insert

epidermal growth factor receptor (EGFR Human)

Expression

Mammalian

Available Since

Feb. 8, 2017

Availability

Academic Institutions and Nonprofits only
TTN gRNA (BRDN0001148405)

Plasmid

#76852

Purpose

3rd generation lentiviral gRNA plasmid targeting human TTN

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TTN (TTN Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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TTN gRNA (BRDN0001146399)

Plasmid

#76853

Purpose

3rd generation lentiviral gRNA plasmid targeting human TTN

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Insert

TTN (TTN Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

July 6, 2016

Availability

Academic Institutions and Nonprofits only

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YT210-FKBP8-gRNA4

Plasmid

#253976

Purpose

Mammalian expression of gRNA targeting mouse Fkbp8 (for CRISPR knockout).

Depositor

Yusuke Hirabayashi

Article

Nakamura et al Nat Commun. 2025 Apr 17;16(1):3401. doi:

Insert

Fkbp8 (Fkbp8 Mouse)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

May 28, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti_Cas9_GFP_UBE2H_sg2

Plasmid

#254543

Purpose

UBE2H knockout

Depositor

Jason Sheltzer

Article

Klaske M. et al bioRxiv 2026.04.26.720636

Insert

UBE2H (UBE2H Human)

Use

CRISPR and Lentiviral

Tags

FLAG-SV40NLS and nucleoplasminNLS-P2A-GFP

Available Since

May 20, 2026

Availability

Academic Institutions and Nonprofits only

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pLenti_Cas9_GFP_CDC7_sg1

Plasmid

#254533

Purpose

CDC7 knockout

Depositor

Jason Sheltzer

Article

Klaske M. et al bioRxiv 2026.04.26.720636

Insert

CDC7 (CDC7 Human)

Use

CRISPR and Lentiviral

Tags

FLAG-SV40NLS and nucleoplasminNLS-P2A-GFP

Available Since

May 11, 2026

Availability

Academic Institutions and Nonprofits only

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lenti-hygro-sgMETTL1-6

Plasmid

#254417

Purpose

Mammalian expression plasmid encoding an sgRNA targeting human METTL1.

Depositor

Rui Su

Article

Ren et al Blood 2025; 146 (Supplement 1): 2539. do

Insert

METTL1 (METTL1 Human)

Use

Lentiviral

Promoter

U6

Available Since

April 8, 2026

Availability

Academic Institutions and Nonprofits only

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pscAAV-KIKO-U6-gTgfbr2-p2a-mCherry-STOPpA-400

Plasmid

#249131

Purpose

all-in-one HDRT-based knockin-knockout (KIKO) design to insert mCherry (=knockin) at gTgfbr2 cut site, disrupting Osmr expression (=knockout)

Depositor

Matthew Krummel

Article

Kuhn et al J Exp Med. 2026 May 4;223(5):e20251228.

Insert

gTgfbr2, mCherry (Tgfbr2 Mouse, Synthetic)

Use

AAV

Available Since

March 4, 2026

Availability

Academic Institutions and Nonprofits only

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pLKO-U6-Letm1shRNA-hPGK-Puro

Plasmid

#215362

Purpose

Expresses a rat Letm1 specific shRNA

Depositor

Jaime de Juan-Sanz

Article

Amrapali Vishwanath et al Nat Metab. 2026 Feb 11. doi: 10.1038/s42

Insert

Letm1 shRNA Target sequence (Letm1 Rat)

Use

Lentiviral

Available Since

Feb. 19, 2026

Availability

Academic Institutions and Nonprofits only

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pLKO-U6-Letm1shRNA-hPGK-mTagBFP2

Plasmid

#215363

Purpose

Expresses a rat Letm1 specific shRNA and a BFP under a separate hPGK promoter

Depositor

Jaime de Juan-Sanz

Article

Amrapali Vishwanath et al Nat Metab. 2026 Feb 11. doi: 10.1038/s42

Insert

Letm1 shRNA Target sequence (Letm1 Rat)

Use

Lentiviral

Expression

Mammalian

Available Since

Feb. 19, 2026

Availability

Academic Institutions and Nonprofits only

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pLKO-U6-Letm1shRNA-hPGK-miRFPnano

Plasmid

#215365

Purpose

Expresses a rat Letm1 specific shRNA and miRFPnano under a separate hPGK promoter

Depositor

Jaime de Juan-Sanz

Article

Amrapali Vishwanath et al Nat Metab. 2026 Feb 11. doi: 10.1038/s42

Insert

Letm1 shRNA Target sequence (Letm1 Rat)

Use

Lentiviral

Expression

Mammalian

Available Since

Feb. 19, 2026

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgETS1-1

Plasmid

#251685

Purpose

gRNA to knock out ETS1 in mammalian cells

Depositor

Boyi Gan

Article

Lei et al Cancer Cell. 2025 Jun 9;43(6):1076-1092.

Insert

ETS1 ETS proto-oncogene 1, transcription factor (ETS1 Human)

Use

CRISPR and Lentiviral

Available Since

Feb. 3, 2026

Availability

Academic Institutions and Nonprofits only

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pLCV2-CDK13(hU6-sg2-mU6-sg3)-Blast

Plasmid

#208348

Purpose

pLentiCRISPRv2-Blast backbone with two separate sgRNAs against CDK13

Depositor

Peter S Nelson

Article

Frank et al eLife 2025

Insert

cyclin dependent kinase 13 (CDK13 Human)

Use

CRISPR and Lentiviral

Promoter

hU6, mU6

Available Since

Jan. 29, 2026

Availability

Academic Institutions and Nonprofits only

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rTTA-gRNA-AAV

Plasmid

#213036

Purpose

This vector contains rTTA expressed under CMV promoter and gRNA expressed under U6 promoter

Depositor

Nadav Ahituv

Article

Nguyen et al Nat Biotechnol. 2025 Feb 4:10.1038/s4158

Insert

rTTA-T2A-mCherry

Use

AAV and CRISPR

Promoter

CMV

Available Since

Oct. 1, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPR-B_2xsgRNAs_ZCRB1 (pAVA3300)

Plasmid

#239325

Purpose

Lentiviral vector expressing Cas9-P2A-Blasticidin and two sgRNA stargeting ZCRB1

Depositor

Andrei Alexandrov

Article

Che et al Nat Commun. 2025 May 22;16(1):4741. doi:

Insert

U6-driven sgRNA1 and 7SK-driven sgRNA2 targeting ZCRB1 (ZCRB1 Human)

Use

CRISPR and Lentiviral

Available Since

Aug. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pKLV2-U6gRNA5(hIKBKG_1k)-PGKpuro2ABFP-W

Plasmid

#208410

Purpose

Lentiviral gRNA plasmid targeting human IKBKG gene, co-expression of BFP tag

Depositor

Sok Ching Cheong

Article

Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

Insert

IKBKG (IKBKG Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Mutation

N/A

Promoter

human U6

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pENTR2b-ITGB1(YYFF)-mRuby2

Plasmid

#215447

Purpose

Gateway entry vector with integrin beta1 NPxY mutant (YYFF) tagged with mRuby2

Depositor

Johanna Ivaska

Article

Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

Insert

ITGB1 (ITGB1 Human)

Use

Gateway Cloning

Tags

mRuby2

Mutation

Mutations in the NPxY sites Y783F, Y795F; Silent …

Promoter

none

Available Since

May 29, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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