We narrowed to 88,055 results for: MAL

1. pLEX_307-SARS-CoV-2-NSP3-V5

   Plasmid

   #214429

   Purpose

   Lentiviral-mediated stable expression of SARS-CoV-2 NSP3 in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   SARS-CoV-2 NSP3 (part of SARS-CoV-2 ORF1ab) (ORF1ab )
   

   Use

   Lentiviral

   Tags

   V5 tag

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pLD-puro-Cc-IFIT5_K197R-VA

   Plasmid

   #191223

   Purpose

   Lentiviral expression of human IFIT5_K197R in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   interferon-induced protein with tetratricopeptide repeats 5 (IFIT5 Human)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   changed Lysine 197 to Arginine (K197R)

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pLD-puro-Cc-SARS-CoV-2_Spike_WT-VA

   Plasmid

   #191216

   Purpose

   Lentiviral expression of SARS-CoV-2 Spike_WT in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   SPIKE_SARS2_WT (S SARS CoV-2)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pLD-puro-Cc-SARS-CoV-2_Spike_Alpha-VA

   Plasmid

   #191217

   Purpose

   Lentiviral expression of SARS-CoV-2 Spike_Alpha in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   SPIKE_SARS2_Alpha (S SARS CoV-2)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   Del 69-70 Del 144 N501Y A570D D614G P681H T716I S…

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pLD-puro-Cc-SARS-CoV-2_Spike_Beta-VA

   Plasmid

   #191218

   Purpose

   Lentiviral expression of SARS-CoV-2 Spike_Beta in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   SPIKE_SARS2_Beta (S SARS CoV-2)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   D80A D215G (Del 241-243) K417N E484K N501Y D614G …

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pLD-puro-Cc-SARS-CoV-2_Spike_Delta-VA

   Plasmid

   #191219

   Purpose

   Lentiviral expression of SARS-CoV-2 Spike_Delta in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   SPIKE_SARS2_Delta (S SARS CoV-2)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   T19R 156del 157del R158G L452R T478K D614G P681R …

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pLD-puro-Cc-SARS-CoV-2_Spike_Lambda-VA

   Plasmid

   #191220

   Purpose

   Lentiviral expression of SARS-CoV-2 Spike_Lambda in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   SPIKE_SARS2_Lambda (S SARS CoV-2)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   G75V T76I Del 246-252 L452Q F490S D614G T859N

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pLD-puro-Cc-IFIT5_WT-VA

   Plasmid

   #191221

   Purpose

   Lentiviral expression of human IFIT5_WT in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   interferon-induced protein with tetratricopeptide repeats 5 (IFIT5 Human)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLD-puro-Cc-IFIT5_K160R-VA

   Plasmid

   #191222

   Purpose

   Lentiviral expression of human IFIT5_K160R in mammalian cells

   Depositor

   Mohan Babu

   Article

   Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

   Insert

   interferon-induced protein with tetratricopeptide repeats 5 (IFIT5 Human)
   

   Use

   Lentiviral

   Tags

   VA tag

   Expression

   Mammalian

   Mutation

   changed Lysine 160 to Arginine (K160R)

   Promoter

   CMV

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pLD-puro-Cc-SARS-CoV-2_NSP3-VA

    Plasmid

    #191214

    Purpose

    Lentiviral expression of SARS-CoV-2 NSP3 in mammalian cells

    Depositor

    Mohan Babu

    Article

    Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

    Insert

    Non structural protein 3 (ORF1ab SARS CoV-2)
    

    Use

    Lentiviral

    Tags

    VA tag

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available Since

    April 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLV-RnSyt1-sgRNA2-dCas9-KRAB-TagBFP2 (identifier AAAA-0246)

    Plasmid

    #202555

    Purpose

    Synaptotagmin-1 sgRNA2 with TagBFP2

    Depositor

    Frederic Meunier

    Article

    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:

    Insert

    CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ - CACCAGTACTCGCGTGCCTCGCACCGG) (Syt1 Rat)
    

    Use

    CRISPR and Lentiviral

    Tags

    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2

    Expression

    Mutation

    Promoter

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pLV-RnSyt1-sgRNA3-dCas9-KRAB-TagBFP2 (Identifier AAAA-0247)

    Plasmid

    #202556

    Purpose

    Synaptotagmin-1 sgRNA3 with TagBFP2

    Depositor

    Frederic Meunier

    Article

    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:

    Insert

    CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ - CACCTCCTCCTGCAGCGGCAGCATCGG) (Syt1 Rat)
    

    Use

    CRISPR and Lentiviral

    Tags

    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2

    Expression

    Mutation

    Promoter

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pLV-RnSyt1-sgRNA1-dCas9-KRAB-TagBFP2 (identifier AAAA-0245)

    Plasmid

    #202554

    Purpose

    Synaptotagmin-1 sgRNA1 with TagBFP2

    Depositor

    Frederic Meunier

    Article

    Joensuu et al EMBO J. 2023 Jul 3;42(13):e112095. doi:

    Insert

    CRISPRi single guide RNA sequence against 5’-UTR of rat synaptotagmin-1 (Syt1) gene (insert 5’ -CACCGCGTGCCTCGCACCGGTCCGCGG) (Syt1 R. norvegius (gRNA))
    

    Use

    CRISPR and Lentiviral

    Tags

    3xFlag (N-terminus of Cas9-KRAB), T2A-TagBFP2

    Expression

    Mutation

    Promoter

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pCXLE-mCherry-t2a-SOX2AV-p2a-KLF4

    Plasmid

    #193295

    Purpose

    episomal vector expressing mCherry + human SOX2A61V + KLF4

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    mCherry-t2a-SOX2AV-p2a-KLF4 (SOX2, KLF4 Human, Discosoma)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    SOX2A61V is a highly cooperative point mutant of …

    Promoter

    CAG

    Available Since

    Dec. 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pcDNA3.3-hAP1 420-440

    Plasmid

    #183643

    Purpose

    To (ectopically) express a mutant of ATP6AP1 lacking the interacting domain with PEN2; mammalian expression

    Depositor

    Sheng-cai Lin

    Article

    Ma et al Nature. 2022 Mar;603(7899):159-165. doi:

    Insert

    ATP6AP1 (ATP6AP1 Human)
    

    Use

    Tags

    myc

    Expression

    Mammalian

    Mutation

    truncated ATP6AP1 mutant; contains only the trans…

    Promoter

    CMV

    Available Since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pCXLE-mCherry-t2a-SOX2-17-p2a-KLF4

    Plasmid

    #193294

    Purpose

    episomal mCherry-hS*K (expressing mCherry + human super-SOX + KLF4) for integration-free naïve conversion

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    mCherry-t2a-SOX2-17-p2a-KLF4 (SOX2, KLF4 Human, Discosoma)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    SOX2-17 is engineered highly cooperative chimeric…

    Promoter

    CAG

    Available Since

    Dec. 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCXLE-Sox2AV-T2A-Klf4-E2A-Myc

    Plasmid

    #210017

    Purpose

    episomal SKM (expressing mouse Sox2-A61V + Klf4 + Myc) for integration-free naïve reset.

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    Sox2AV-t2a-Klf4-e2a-cMyc (Klf4, Sox2 Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Sox2A61V is a point mutant of Sox2 that enhances …

    Promoter

    CAG

    Available Since

    Dec. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pCXLE-SOX2-17-p2a-KLF4

    Plasmid

    #193290

    Purpose

    episomal hS*K (expressing human super-SOX + KLF4) for enhanced generation of intergration-free iPSCs or for integration-free naïve conversion

    Depositor

    Hans Schöler

    Article

    MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

    Insert

    SOX2-17-p2a-KLF4 (SOX2, KLF4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    SOX2-17 is engineered highly cooperative chimeric…

    Promoter

    CAG

    Available Since

    Dec. 13, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pACEMam2-TRPML1

    Plasmid

    #238303

    Purpose

    Expression of human TRPML1 in mammalian cells

    Depositor

    Pravin Mahajan

    Article

    Judith et al Structure, 2025

    Insert

    TRPML1 (MCOLN1 Human)
    

    Use

    Tags

    8xHis-3xFLAG-TEV

    Expression

    Mammalian

    Mutation

    Promoter

    hybrid CAG promoter

    Available Since

    June 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCAG-denAsCas12a(E174R/S542R/K548R/D908A)-NLS(nuc)-3xHA-VPR (RTW776)

    Plasmid

    #107943

    Purpose

    Mammalian expression plasmid for human codon optimized DNase-inactive enAsCas12a (enhanced AsCas12a) fused to the VPR activation domain, encoding E174R/S542R/K548R/D908A substitutions

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Kleinstiver et al Nat Biotechnol. 2019 Feb 11. pii: 10.103

    Insert

    human codon optimized DNase-inactive (D908A) enAsCas12a (E174R/S542R/K548R) fused to VPR activation domain
    

    Use

    Tags

    3x HA, NLS (nucleoplasmin), and VPR (VP64-p65-Rta…

    Expression

    Mammalian

    Mutation

    E174R, S542R, K548R and D908A

    Promoter

    CAG

    Available Since

    Feb. 11, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge