We narrowed to 461 results for: LEP

1. pENTR-TARDBP-G287A

   Plasmid

   #141323

   Purpose

   Gateway cloning of TARDBP-G287A

   Depositor

   Mohan Babu

   Article

   Pourhaghighi et al Cell Syst. 2020 Apr 22;10(4):333-350.e14

   Insert

   TARDBP-G287A (TARDBP Human)
   

   Use

   Gateway cloning

   Mutation

   G287A

   Available Since

   June 17, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. px552-U6-gRNA1-CMV-eGFP

   Plasmid

   #211758

   Purpose

   sgRNA1 targeting Exon 1 of VEGFA gene conserved across mouse, rhesus macaque, and human.

   Depositor

   Glenn Yiu

   Article

   Chung et al Mol Ther Nucleic Acids. 2022 Apr 27;28:6

   Insert

   gRNA1 targeting VEGF-A (VEGFA Human, Mouse, M. mulatta (rhesus macaque))
   

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. px552-U6-gRNA2-CMV-eGFP

   Plasmid

   #211759

   Purpose

   sgRNA2 targeting Exon 1 of VEGFA gene conserved across mouse, rhesus macaque, and human.

   Depositor

   Glenn Yiu

   Article

   Chung et al Mol Ther Nucleic Acids. 2022 Apr 27;28:6

   Insert

   gRNA2 targeting VEGF-A (VEGFA Human, Mouse, M. mulatta (rhesus macaque))
   

   Use

   AAV and CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLD-puro-Cc-TARDBP-WT_VA

   Plasmid

   #141327

   Purpose

   Lentiviral vector for expression of C-terminally VA-tagged human TARDBP-WT in mammalian cells

   Depositor

   Mohan Babu

   Article

   Pourhaghighi et al Cell Syst. 2020 Apr 22;10(4):333-350.e14

   Insert

   TARDBP-WT (TARDBP Human)
   

   Use

   Lentiviral

   Tags

   VA tag (Beacon-2XStrep-6XHis-2XTEV-3XFLAG)

   Expression

   Mammalian

   Available Since

   June 9, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA3_N-DYK_MTHFD1-NLS

   Plasmid

   #133023

   Purpose

   NLS sequence was fused to MTHFD1-wild type through site-directed mutagenesis (Q5 Site-Directed Mutagenesis Kit, New England Biolabs)

   Depositor

   Stefan Kubicek

   Article

   Sdelci et al Nat Genet. 2019 Jun;51(6):990-998. doi:

   Insert

   MTHFD1 (MTHFD1 Human)
   

   Tags

   NLS

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 2, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA3_N-DYK_MTHFD1-NES

   Plasmid

   #133022

   Purpose

   NES sequence was fused to MTHFD1-wild type through site-directed mutagenesis (Q5 Site-Directed Mutagenesis Kit, New England Biolabs)

   Depositor

   Stefan Kubicek

   Article

   Sdelci et al Nat Genet. 2019 Jun;51(6):990-998. doi:

   Insert

   MTHFD1 (MTHFD1 Human)
   

   Tags

   NES

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 2, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCAGGS SARS-CoV-2 BA.4/5 Spike

   Plasmid

   #186031

   Purpose

   Expresses codon-optimized full length SARS-CoV-2 BA.4/5 Spike

   Depositor

   Marceline Côté

   Article

   Tauzin et al Cell Rep. 2023 Jan 31;42(1):111998. doi:

   Insert

   SARS-CoV-2 BA.4/5 Spike (S )
   

   Expression

   Mammalian

   Mutation

   BA.2 mutations (T19I, LPPA24S, G142D, V213G, G339…

   Promoter

   chicken β-actin promoter, CMV enhancer

   Available Since

   June 8, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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8. pCAGGS SARS-CoV-2 BQ.1.1 Spike

   Plasmid

   #193710

   Purpose

   Expresses codon-optimized full length SARS-CoV-2 BQ.1.1 Spike

   Depositor

   Marceline Côté

   Article

   Tauzin et al Cell Rep. 2023 Jan 31;42(1):111998. doi:

   Insert

   SARS-CoV-2 BQ.1.1 Spike (S )
   

   Expression

   Mammalian

   Mutation

   Contains the following mutations: T19I, LPPA24S, …

   Promoter

   chicken β-actin promoter, CMV enhancer

   Available Since

   Nov. 21, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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9. pLD-puro-Cc-TARDBP-A315T_VA

   Plasmid

   #141329

   Purpose

   Lentiviral vector for expression of C-terminally VA-tagged human TARDBP-A315T in mammalian cells

   Depositor

   Mohan Babu

   Article

   Pourhaghighi et al Cell Syst. 2020 Apr 22;10(4):333-350.e14

   Insert

   TARDBP-A315T (TARDBP Human)
   

   Use

   Lentiviral

   Tags

   VA tag (Beacon-2XStrep-6XHis-2XTEV-3XFLAG)

   Expression

   Mammalian

   Mutation

   A315T

   Available Since

   June 9, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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10. pCAGGS SARS-CoV-2 BA.4.6 Spike

    Plasmid

    #190013

    Purpose

    Expresses codon-optimized full length SARS-CoV-2 BA.4.6 Spike

    Depositor

    Marceline Côté

    Article

    Tauzin et al Cell Rep. 2023 Jan 31;42(1):111998. doi:

    Insert

    SARS-CoV-2 BA.4.6 Spike (S )
    

    Expression

    Mammalian

    Mutation

    Contains the following mutations: T19I, LPPA24S, …

    Promoter

    chicken β-actin promoter, CMV enhancer

    Available Since

    Sept. 7, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. pLD-puro-Cc-TARDBP-G368A_VA

    Plasmid

    #141330

    Purpose

    Lentiviral vector for expression of C-terminally VA-tagged human TARDBP-G368A in mammalian cells

    Depositor

    Mohan Babu

    Article

    Pourhaghighi et al Cell Syst. 2020 Apr 22;10(4):333-350.e14

    Insert

    TARDBP-G368A (TARDBP Human)
    

    Use

    Lentiviral

    Tags

    VA tag (Beacon-2XStrep-6XHis-2XTEV-3XFLAG)

    Expression

    Mammalian

    Mutation

    G368A

    Available Since

    June 9, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLD-puro-Cc-TARDBP-G287A_VA

    Plasmid

    #141328

    Purpose

    Lentiviral vector for expression of C-terminally VA-tagged human TARDBP-G287A in mammalian cells

    Depositor

    Mohan Babu

    Article

    Pourhaghighi et al Cell Syst. 2020 Apr 22;10(4):333-350.e14

    Insert

    TARDBP-G287A (TARDBP Human)
    

    Use

    Lentiviral

    Tags

    VA tag (Beacon-2XStrep-6XHis-2XTEV-3XFLAG)

    Expression

    Mammalian

    Mutation

    G287A

    Available Since

    June 9, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLD-puro-Cc-TARDBP-W385G_VA

    Plasmid

    #141331

    Purpose

    Lentiviral vector for expression of C-terminally VA-tagged human TARDBP-W385G in mammalian cells

    Depositor

    Mohan Babu

    Article

    Pourhaghighi et al Cell Syst. 2020 Apr 22;10(4):333-350.e14

    Insert

    TARDBP-W385G (TARDBP Human)
    

    Use

    Lentiviral

    Tags

    VA tag (Beacon-2XStrep-6XHis-2XTEV-3XFLAG)

    Expression

    Mammalian

    Mutation

    W385G

    Available Since

    June 9, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pCAGGS SARS-CoV-2 BA.2 Spike

    Plasmid

    #185604

    Purpose

    Expresses codon-optimized full length SARS-CoV-2 BA.2 Spike

    Depositor

    Marceline Côté

    Article

    Tauzin et al Cell Rep. 2022 Oct 25;41(4):111554. doi:

    Insert

    SARS-CoV-2 BA.2 Spike (S )
    

    Expression

    Mammalian

    Mutation

    T19I, L24S, Δ25-27, G142D, V213G, G339D, S371F, S…

    Promoter

    chicken β-actin promoter, CMV enhancer

    Available Since

    July 21, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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15. pCAGGS SARS-CoV-2 BA.2.75 Spike

    Plasmid

    #190012

    Purpose

    Expresses codon-optimized full length SARS-CoV-2 BA.2.75 Spike

    Depositor

    Marceline Côté

    Article

    Tauzin et al Cell Rep. 2023 Jan 31;42(1):111998. doi:

    Insert

    SARS-CoV-2 BA.2.75 Spike (S )
    

    Expression

    Mammalian

    Mutation

    Contains the BA.2 mutations (T19I, LPPA24S, G142D…

    Promoter

    chicken β-actin promoter, CMV enhancer

    Available Since

    Sept. 7, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

16. pCAGGS SARS-CoV-2 BA.1 Spike

    Plasmid

    #185452

    Purpose

    Expresses codon-optimized full length SARS-CoV-2 BA.1 Spike

    Depositor

    Marceline Côté

    Article

    Chatterjee et al Cell Rep. 2022 Mar 1;38(9):110429. doi:

    Insert

    SARS-CoV-2 Spike BA.1 (S )
    

    Expression

    Mammalian

    Mutation

    Contains the following mutations: A67V, Δ69-70, T…

    Promoter

    chicken β-actin promoter, CMV enhancer

    Available Since

    June 8, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

17. pSpot2

    Plasmid

    #117063

    Purpose

    For expression of proteins with C-terminal Spot-Tag in E. coli

    Depositor

    Felix Hartlepp

    Type

    Empty backbone

    Tags

    Spot-Tag

    Expression

    Bacterial

    Available Since

    Oct. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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18. pSpot8

    Plasmid

    #117064

    Purpose

    For expression of proteins with C-terminal Spot-Tag in S. cerevisiae

    Depositor

    Felix Hartlepp

    Type

    Empty backbone

    Tags

    Spot-Tag

    Expression

    Yeast

    Available Since

    Oct. 4, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. pENTR-Flippase-myc

    Plasmid

    #139548

    Purpose

    Flippase-myc fusion ORF with stop codon between attL1-attL2 on Gateway entry vector

    Depositor

    Minoru Ko

    Insert

    Fleppase-myc
    

    Use

    Cre/Lox

    Available Since

    March 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. pSpot-Tag-GFP-GPI

    Plasmid

    #117061

    Purpose

    For mammalian expression of GPI-anchored GFP with N-terminal Spot-Tag

    Depositor

    Felix Hartlepp

    Insert

    GPI-anchored GFP
    

    Tags

    GPI-anchor and Spot-Tag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 4, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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