We narrowed to 115 results for: mutant p53

1. pDD2708

   Plasmid

   #175081

   Purpose

   Mammalian expression of Flag-tagged KSHV ORF45 RN1 mutant

   Depositor

   Dirk Dittmer

   Article

   Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

   Insert

   KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   RN1 mutant: V284A/L285A

   Promoter

   Available since

   Feb. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pDD2710

   Plasmid

   #175082

   Purpose

   Mammalian expression of Flag-tagged KSHV ORF45 RN2 mutant

   Depositor

   Dirk Dittmer

   Article

   Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

   Insert

   KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   RN2 mutant: I289A/L291A

   Promoter

   Available since

   Feb. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLenti_EF1a_Flag_EGFP

   Plasmid

   #183117

   Purpose

   Expresses flag-tagged EGFP in mammalian cells

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   EGFP
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pLentiGuide_GFP_NT135

   Plasmid

   #183118

   Purpose

   pLentiGuide modified to express GFP and a non-targeting sgRNA

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   NT135
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pLentiGuide_mCherry_NT135

   Plasmid

   #183121

   Purpose

   pLentiGuide modified to express mCherry and a non-targeting sgRNA

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   NT135
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pLentiCRISPR_Puro_sgAAVS1

   Plasmid

   #187818

   Purpose

   pLentiCRISPR that is selectable with puromycin with an sgRNA targeting AAVS1

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   sgAAVS1
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pLentiGuide_mCherry_sgEPAS1#1

   Plasmid

   #183122

   Purpose

   pLentiGuide modified to express mCherry and an sgRNA targeting EPAS1

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   sgEPAS1-1
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. mLPx-shZMPSTE24

   Plasmid

   #69067

   Purpose

   encodes a shRNA against the protease ZMPSTE24

   Depositor

   Gerardo Ferbeyre

   Article

   Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

   Insert

   shRNA against ZMPSTE24 (ZMPSTE24 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   PGK

   Available since

   Jan. 5, 2016

   Availability

   Academic Institutions and Nonprofits only

9. pLentiGuide_GFP_sgEPAS1#1

   Plasmid

   #183119

   Purpose

   pLentiGuide modified to express GFP and an sgRNa targeting EPAS1

   Depositor

   William Kaelin

   Article

   Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

   Insert

   sgEPAS1-1
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   Aug. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pLentiGuide_mCherry_sgEPAS1#2

    Plasmid

    #183123

    Purpose

    pLentiGuide modified to express mCherry and an sgRNA targeting EPAS1

    Depositor

    William Kaelin

    Article

    Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

    Insert

    sgEPAS1-2
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLPC-Progerin

    Plasmid

    #69061

    Purpose

    encodes the lamin A mutant with a 50 amino acids deletion responsible for the Hutchinson-Gilford Progeria Syndrome

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    Progerin (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Dec. 15, 2015

    Availability

    Academic Institutions and Nonprofits only

12. pLPC-S22A-Progerin

    Plasmid

    #69065

    Purpose

    encodes a Progerin mutant where serine 22 is mutated to an alanine

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    Progerin (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Progerin with serine 22 mutated to alanine

    Promoter

    CMV

    Available since

    Dec. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

13. pLPC-S22A-LaminA

    Plasmid

    #69066

    Purpose

    encodes a mutant lamin A where serine 22 is mutated to a an alanine

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    LaminA (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    serine 22 mutated in alanine

    Promoter

    CMV

    Available since

    Dec. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

14. pLPC-L647RLaminA

    Plasmid

    #69060

    Purpose

    encodes a lamin A mutant with Leucine 647 mutated to an Arginin

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    LaminA (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Lamin A with Leucine 647 mutated to Arginine

    Promoter

    CMV

    Available since

    Dec. 15, 2015

    Availability

    Academic Institutions and Nonprofits only

15. pLPC-L647RLaminA-CS

    Plasmid

    #69062

    Purpose

    encodes a lamin A mutant with Leucine 647 mutated to an Arginin and with a substitution of cysteine in CaaX-motif by a serine

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    LaminA (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Lamin A with Leucine 647 mutated to Arginine and …

    Promoter

    CMV

    Available since

    Dec. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

16. pLPC-S22AProgerin-CS

    Plasmid

    #69063

    Purpose

    encodes a Progerin mutant with serine 22 mutated to an alanine and with a substitution of cysteine in CaaX-motif by a serine

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    Progerin (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Progerin with serine 22 mutated to alanine and wi…

    Promoter

    CMV

    Available since

    Dec. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

17. pLenti_EF1a_EV

    Plasmid

    #183116

    Purpose

    Empty vector control for pLenti_EF1a constructs

    Depositor

    William Kaelin

    Article

    Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

    Insert

    Small multiple cloning site
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLentiCRISPR_zeo_sgNT135

    Plasmid

    #183181

    Purpose

    pLentiCRISPR that is selectable with zeocin with a non-targeting sgRNA

    Depositor

    William Kaelin

    Article

    Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

    Insert

    NT135
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLentiGuide_GFP_sgEPAS1#2

    Plasmid

    #183120

    Purpose

    pLentiGuide modified to express GFP and an sgRNA targeting EPAS1

    Depositor

    William Kaelin

    Article

    Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

    Insert

    EPAS1-2
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. MSCV Myc T58A puro

    Plasmid

    #18773

    Depositor

    Scott Lowe

    Article

    Hemann et al Nature. 2005 Aug 11. 436(7052):807-11.

    Insert

    myc T58A (MYC Human)
    

    Use

    Retroviral

    Tags

    3xHA

    Expression

    Mammalian

    Mutation

    T58A

    Promoter

    Available since

    July 3, 2008

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. MSCV Myc IRES GFP

    Plasmid

    #18770

    Depositor

    Scott Lowe

    Article

    Hemann et al Nature. 2005 Aug 11. 436(7052):807-11.

    Insert

    Myc (Myc Mouse)
    

    Use

    Retroviral

    Tags

    IRES GFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 3, 2008

    Availability

    Academic Institutions and Nonprofits only

22. pLPC-LaminA

    Plasmid

    #69059

    Purpose

    encodes the lamin A protein

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    LaminA (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Dec. 15, 2015

    Availability

    Academic Institutions and Nonprofits only

23. MSCV Myc P57S IRES GFP

    Plasmid

    #18771

    Depositor

    Scott Lowe

    Article

    Hemann et al Nature. 2005 Aug 11. 436(7052):807-11.

    Insert

    myc P57S (MYC Human)
    

    Use

    Retroviral

    Tags

    IRES GFP

    Expression

    Mammalian

    Mutation

    P57S

    Promoter

    Available since

    July 3, 2008

    Availability

    Academic Institutions and Nonprofits only

24. pX61

    Plasmid

    #46852

    Purpose

    TOP Hupki-puro2A-Hupki-wt plasmid

    Depositor

    Monica Hollstein

    Article

    Wei et al Cell Cycle. 2011 Apr 15;10(8):1261-70. E

    Insert

    attB-Puro-2A and Hupki p53 wild type (TP53 Mouse, Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 21, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pX41

    Plasmid

    #46851

    Purpose

    TOP Hupki-wt plasmid without selection marker

    Depositor

    Monica Hollstein

    Article

    Wei et al Cell Cycle. 2011 Apr 15;10(8):1261-70. E

    Insert

    attB and Hupki p53 wild type (TP53 Mouse, Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 21, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pcDNA3-DM-TRAF

    Plasmid

    #16377

    Depositor

    Wafik El-Deiry

    Article

    Sax et al J Biol Chem. 2003 Sep 19. 278(38):36435-

    Insert

    TRAF4 (TRAF4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    TRAF domain deletion mutant

    Promoter

    Available since

    Dec. 14, 2007

    Availability

    Academic Institutions and Nonprofits only

27. pcDNA3-DM-RING

    Plasmid

    #16376

    Depositor

    Wafik El-Deiry

    Article

    Sax et al J Biol Chem. 2003 Sep 19. 278(38):36435-

    Insert

    TRAF4 (TRAF4 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    RING domain deletion mutant

    Promoter

    Available since

    Dec. 14, 2007

    Availability

    Academic Institutions and Nonprofits only

28. pLPC-Progerin-CS

    Plasmid

    #69064

    Purpose

    encodes Progerin with a substitution of cysteine in CaaX-motif by a serine

    Depositor

    Gerardo Ferbeyre

    Article

    Moiseeva et al Cell Cycle. 2015 Aug 3;14(15):2408-21. d

    Insert

    Progerin (LMNA Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    Progerin with substitution of cysteine in CaaX-mo…

    Promoter

    CMV

    Available since

    Dec. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

29. pCMV HDM2(C464A)

    Plasmid

    #12086

    Depositor

    Tyler Jacks

    Article

    Boyd et al Nat Cell Biol. 2000 Sep . 2(9):563-8.

    Insert

    HDM2 (MDM2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    C464A: RING-finger-domain mutant

    Promoter

    Available since

    June 8, 2006

    Availability

    Academic Institutions and Nonprofits only

30. pICE-HA-Ku70-siR-Mut6E

    Plasmid

    #82330

    Purpose

    Plasmid for constitutive or doxy-inducible expression of mutant human Ku70 unable to bind DNA and resistant to siRNA. Confers resistance to puro. Use T-REx cells for doxycycline-inducible expression.

    Depositor

    Sébastien Britton, Patrick Calsou

    Article

    Lamaa et al EMBO Rep. 2016 Apr;17(4):508-18. doi: 10

    Insert

    Ku70 (XRCC6 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Mut6E corresponding to K282E K287E T300E K331E K3…

    Promoter

    CMV-tet

    Available since

    Sept. 13, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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