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We narrowed to 30,777 results for: Eng

Showing: 1451 - 1500 of 30777 results

  1. pSCBE3-Hypa

    Plasmid
    #218157
    Purpose
    This plasmid harbors the base editor SCBE3-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing in Streptomyces.
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    scbe3-Hypa
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutations in the portion of SpCas9 : D10A / N692A…
    Promoter
    rpsL promoter
    Available since
    May 10, 2024
    Availability
    Academic Institutions and Nonprofits only
    218157-plasmid-map-sequence-id-433172

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  5. pSCBE3-NG-HF1

    Plasmid
    #218160
    Purpose
    This plasmid harbors the base editor SCBE3-NG-HF1 along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    scbe3-NG-HF1
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutations in the portion of SpCas9 : D10A / N497A…
    Promoter
    rpsL promoter
    Available since
    May 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    218160-plasmid-map-sequence-id-433202

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  6. pSCBE3-NG-Hypa

    Plasmid
    #218161
    Purpose
    This plasmid harbors the base editor SCBE3-NG-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    scbe3-NG-Hypa
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutations in the portion of SpCas9 : D10A / N692A…
    Promoter
    rpsL promoter
    Available since
    May 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    218161-plasmid-map-sequence-id-433271

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  9. peSCBE3-NG-Hypa

    Plasmid
    #218165
    Purpose
    This plasmid harbors the base editor eSCBE3-NG-Hypa along with an sgRNA cloning cassette, facilitating high-efficiency and high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    escbe3-NG-Hypa
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutation in the portion of deaminase hAPOBEC3A : …
    Promoter
    rpsL promoter
    Available since
    May 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    218165-plasmid-map-sequence-id-433201

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  11. peSCBE3-NG-HF1-Hypa

    Plasmid
    #218166
    Purpose
    This plasmid harbors the base editor eSCBE3-NG-HF1-Hypa along with an sgRNA cloning cassette, facilitating high-efficiency and high-fidelity base editing at targets bearing NG PAM in Streptomyces.
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    escbe3-NG-HF1-Hypa
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutation in the portion of deaminase hAPOBEC3A : …
    Promoter
    rpsL promoter
    Available since
    May 15, 2024
    Availability
    Academic Institutions and Nonprofits only
    218166-plasmid-map-sequence-id-433270

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  12. peSCBE3-NG-HF1

    Plasmid
    #218164
    Purpose
    This plasmid harbors the base editor eSCBE3-NG-HF1 along with an sgRNA cloning cassette, facilitating high-efficiency and high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    escbe3-NG-HF1
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutation in the portion of deaminase hAPOBEC3A : …
    Promoter
    rpsL promoter
    Available since
    May 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    218164-plasmid-map-sequence-id-433171

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  19. pCDH-3_Flag-YTHDF2-D-MUT (nonsense mutation of sgYTHDF2-1)

    Plasmid
    #232947
    Purpose
    Expresses the domain-mutant YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown
    Depositor
    Jianjun Chen
    Article
    Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.
    Insert
    YTHDF2-D-MUT (YTHDF2 Human)
    Use
    Lentiviral
    Tags
    Expression
    Mutation
    5 site mutation (Y418A+D422A+W432A+W486A+W491A), …
    Promoter
    Available since
    May 16, 2025
    Availability
    Academic Institutions and Nonprofits only
    232947-plasmid-map-sequence-id-473043

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  21. pCDH-3_Flag-YTHDF2-m(6)A-MUT (nonsense mutation of sgYTHDF2-1)

    Plasmid
    #232946
    Purpose
    Expresses the m6A-binding-deficient mutant of YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown
    Depositor
    Jianjun Chen
    Article
    Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.
    Insert
    YTHDF2-m(6)A-MUT (YTHDF2 Human)
    Use
    Lentiviral
    Tags
    Expression
    Mutation
    2 site mutation (W432A+W486A), synonymous mutation
    Promoter
    Available since
    May 16, 2025
    Availability
    Academic Institutions and Nonprofits only
    232946-plasmid-map-sequence-id-473041

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  23. pSCBE3-NG-HF1-Hypa

    Plasmid
    #218162
    Purpose
    This plasmid harbors the base editor SCBE3-NG-HF1-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces.
    Depositor
    Yuhui Sun
    Article
    Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:
    Inserts
    scbe3-NG-HF1-Hypa
    a programmable sgRNA cloning cassette
    Use
    CRISPR; Sgrna transcription
    Tags
    Expression
    Bacterial
    Mutation
    Mutations in the portion of SpCas9 : D10A / N497A…
    Promoter
    rpsL promoter
    Available since
    May 13, 2024
    Availability
    Academic Institutions and Nonprofits only
    218162-plasmid-map-sequence-id-433200

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  24. pJOP-HTT-HR65Q

    Plasmid
    #92249
    Purpose
    HTT donor DNA with 65Q for homologous recombination-mediated gene modification
    Depositor
    Mahmoud Pouladi
    Article
    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7
    Insert
    HTT donor DNA (HTT Human)
    Use
    Precisionx hr targeting vector
    Tags
    Expression
    Mutation
    Barcode of wobble bases to prevent TALEN cleaving…
    Promoter
    Available since
    Feb. 26, 2019
    Availability
    Academic Institutions and Nonprofits only
    92249-plasmid-map-sequence-id-182406

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  25. pJOP-HTT-HR45Q

    Plasmid
    #92248
    Purpose
    HTT donor DNA with 45Q for homologous recombination-mediated gene modification
    Depositor
    Mahmoud Pouladi
    Article
    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7
    Insert
    HTT donor DNA (HTT Human)
    Use
    Precisionx hr targeting vector
    Tags
    Expression
    Mutation
    Barcode of wobble bases to prevent TALEN cleaving…
    Promoter
    Available since
    Feb. 26, 2019
    Availability
    Academic Institutions and Nonprofits only
    92248-plasmid-map-sequence-id-182404

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  26. pJOP-HTT-HR81Q

    Plasmid
    #92250
    Purpose
    HTT donor DNA with 81Q for homologous recombination-mediated gene modification
    Depositor
    Mahmoud Pouladi
    Article
    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7
    Insert
    HTT donor DNA (HTT Human)
    Use
    Precisionx hr targeting vector
    Tags
    Expression
    Mutation
    Barcode of wobble bases to prevent TALEN cleaving…
    Promoter
    Available since
    Feb. 26, 2019
    Availability
    Academic Institutions and Nonprofits only
    92250-plasmid-map-sequence-id-315766

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  27. pJOP-HTT-HR30Q

    Plasmid
    #92247
    Purpose
    HTT donor DNA with 30Q for homologous recombination-mediated gene modification
    Depositor
    Mahmoud Pouladi
    Article
    Ooi et al Cell Rep. 2019 Feb 26;26(9):2494-2508.e7
    Insert
    HTT donor DNA (HTT Human)
    Use
    Precisionx hr targeting vector
    Tags
    Expression
    Mutation
    Barcode of wobble bases to prevent TALEN cleaving…
    Promoter
    Available since
    Feb. 26, 2019
    Availability
    Academic Institutions and Nonprofits only
    92247-plasmid-map-sequence-id-182400

    Enlarge

  29. pCDH-3_Flag-YTHDF2-RNA-MUT (nonsense mutation of sgYTHDF2-1)

    Plasmid
    #232948
    Purpose
    Expresses the RNA-binding-deficient mutant of YTHDF2 with synonymous mutations for resistance against sgYTHDF2-1-mediated knockdown
    Depositor
    Jianjun Chen
    Article
    Chen et al Cell. 2024 Dec 12:S0092-8674(24)01324-2.
    Insert
    YTHDF2-RNA-MUT (YTHDF2 Human)
    Use
    Lentiviral
    Tags
    Expression
    Mutation
    RNA binding mutation (K416A+R527A), synonymous mu…
    Promoter
    Available since
    May 16, 2025
    Availability
    Academic Institutions and Nonprofits only
    232948-plasmid-map-sequence-id-473044

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  32. pAAV-CAG-2xNLS-tdTomato-WPRE-hGHpolyA

    Plasmid
    #192552
    Purpose
    Expresses nuclear localized tdTomato under CAG promoter
    Depositor
    Guoping Feng
    Has Service
    AAV PHP.eB and AAV9
    Insert
    tdTomato
    Use
    AAV
    Tags
    NLS
    Expression
    Mutation
    deleted E273 and G274 compared to FPbase ID: PGG5S
    Promoter
    CAG
    Available since
    Nov. 29, 2022
    Availability
    Academic Institutions and Nonprofits only
    192552-plasmid-map-sequence-id-403193

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Showing: 1451 - 1500 of 30777 results