We narrowed to 1,372 results for: ABE8e

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pRDB_092

Plasmid

#231110

Purpose

C>T base editor

Depositor

John Doench, David Root

Publication

Kaplan et al Nat Genet. 2025 Nov;57(11):2920-2929. do

Insert

TadA-CDd-nCas9-SpG-UGI

Use

CRISPR and Lentiviral

Mutation

D10A

Available since

Jan. 30, 2025

Availability

Academic Institutions and Nonprofits only

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pT3TS-spCas9 ABE-Umax-ex1

Plasmid

#222141

Purpose

Adenine base editor with modified TadA variant for extended window for A-to-G base editing in zebrafish

Depositor

Gaurav Varshney

Publication

Qin et al Nat Commun. 2024 Jul 4;15(1):5613. doi:

Insert

Modified TadA-nSpCas9

Use

CRISPR; Zebrafish expression

Tags

Bipartite NLS

Promoter

T3

Available since

Aug. 19, 2024

Availability

Academic Institutions and Nonprofits only

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SpCas9-CBE6c-IVT

Plasmid

#215835

Purpose

Template for in vitro transcription of CBE6c (with SpCas9)

Depositor

David Liu

Publication

Zhang et al Nat Commun. 2024 Feb 24;15(1):1697. doi:

Insert

CBE6c-SpCas9-2xUGI

Use

In vitro transcription template

Available since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

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SpCas9-CBE6a-V106W

Plasmid

#215824

Purpose

Express CBE6a-V106W (with SpCas9) in mammalian cells

Depositor

David Liu

Publication

Zhang et al Nat Commun. 2024 Feb 24;15(1):1697. doi:

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

CBE6a V106W-SpCas9-2xUGI (cas9 )

Use

In vitro transcription template

Available since

March 8, 2024

Availability

Academic Institutions and Nonprofits only

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SpCas9-CBE6c

Plasmid

#215821

Purpose

Express CBE6c (with SpCas9) in mammalian cells

Depositor

David Liu

Publication

Zhang et al Nat Commun. 2024 Feb 24;15(1):1697. doi:

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

CBE6c-SpCas9-2xUGI (cas9 )

Expression

Mammalian

Available since

March 8, 2024

Availability

Academic Institutions and Nonprofits only

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pET28a-6xHis-MBP-TEV site-TadA8e

Plasmid

#208319

Purpose

Overxpression MBP-TadA8e

Depositor

Weixin Tang

Publication

Xiao et al Nat Biotechnol. 2024 Jan 2. doi: 10.1038

Insert

TadA8e

Expression

Bacterial

Mutation

mutations in TadA are described in the paper

Available since

Jan. 2, 2024

Availability

Academic Institutions and Nonprofits only

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pIRESpuroN3xFLAG-His-CDK5RAP3

Plasmid

#204555

Purpose

Expresses 3xFLAG-His-tagged CDK5RAP3 in mammalian cells

Depositor

Masaaki Komatsu

Publication

Ishimura et al Nat Commun. 2022 Dec 21;13(1):7857. doi:

Insert

CDK5RAP3 (AMY2A Human)

Expression

Mammalian

Mutation

none

Available since

Aug. 14, 2023

Availability

Academic Institutions and Nonprofits only

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pDV05.2_pEF1a-iRFP720_secreted

Plasmid

#200409

Purpose

Expresses a secreted version of iRFP720 constitutively in mammalian cells

Depositor

James Collins

Publication

Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

iRFP720 (secreted)

Use

Synthetic Biology

Expression

Mammalian

Available since

June 30, 2023

Availability

Academic Institutions and Nonprofits only

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Mammalian_SpCas9_Target-AID2S

Plasmid

#188648

Purpose

Expresses SpCas9_Target-AID2S in mammalian cells

Depositor

Keiji Nishida

Publication

Li et al Nat Commun. 2022 Aug 8;13(1):4531. doi:

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

nCas9-AID2S-UGI

Tags

UGI

Expression

Mammalian

Mutation

D10A for SpCas9

Promoter

pCMV

Available since

Oct. 31, 2022

Availability

Academic Institutions and Nonprofits only

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pCMV-E1347A-nCas9(D10A)-UGI

Plasmid

#187410

Purpose

DddA E1347A variant

Depositor

Jin-Soo Kim

Publication

Mok et al Nat Commun. 2022 Jul 12;13(1):4038. doi:

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

DddA E1347A variant

Use

CRISPR

Expression

Mammalian

Available since

Aug. 4, 2022

Availability

Academic Institutions and Nonprofits only

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pCMV-ND1 Left -GSVG-UGI

Plasmid

#187412

Purpose

human mitochondrial DNA ND1 target TALE

Depositor

Jin-Soo Kim

Publication

Mok et al Nat Commun. 2022 Jul 12;13(1):4038. doi:

Insert

DddA GSVG variant

Expression

Mammalian

Available since

Aug. 4, 2022

Availability

Academic Institutions and Nonprofits only

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pLKO‐puro‐2A‐mdx4cv‐GFP

Plasmid

#187053

Purpose

fluorescent reporter for adenine base editing of mdx4cv point mutation

Depositor

Renzhi Han

Publication

Xu et al Nat Commun. 2021 Jun 17;12(1):3719. doi:

Insert

GFP

Use

Lentiviral

Expression

Mammalian

Promoter

CMV

Available since

July 22, 2022

Availability

Academic Institutions and Nonprofits only

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epi-ABEmax

Plasmid

#135974

Purpose

Expresses ABEmax, EBNA1 and blasticidin resistence gene; cloning backbone for sgRNA; Contains Epstein-Barr virus oriP replication origin

Depositor

Yongming Wang

Publication

Qi et al Front Cell Dev Biol. 2020 Sep 25;8:59058

Type

Empty backbone

Expression

Mammalian

Available since

May 5, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

2 Articles
pF3BGX-T2A-p65-AD

Plasmid

#138395

Purpose

RMCE vector for generating C-terminal T2A-p65-AD fusion (split GAL4)

Depositor

Shu Kondo

Publication

Kondo et al Cell Rep. 2020 Jan 7;30(1):284-297.e5. d

Insert

T2A-p65-AD

Expression

Insect

Available since

March 19, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pBT138b-proD

Plasmid

#138516

Purpose

P3e

Depositor

David Liu

Publication

Richter et al Nat Biotechnol. 2020 Jul;38(7):883-891.

Insert

T7-RNAP

Use

Synthetic Biology

Available since

March 16, 2020

Availability

Academic Institutions and Nonprofits only

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pLenti-FNLSHiFiNG-P2A-Puro

Plasmid

#136903

Purpose

Lentivirus for constitutive expression of FNLSHiFiNG in mammalian cells (codon optimized)

Depositor

Lukas Dow

Publication

Katti et al Nucleic Acids Res. 2020 Feb 29. pii: 576

Insert

FNLSHiFiNG

Use

Lentiviral

Tags

FLAG-NLS and NLS

Mutation

R691A,L1111R,D1135V,G1218R,E1219F,A1322R,R1335V,T…

Promoter

EF1s

Available since

Feb. 10, 2020

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pCBEclos-cbei2385-g2-opt

Plasmid

#118215

Purpose

CRISPR-mediated base editing in Clostridium

Depositor

Sheng Yang

Publication

Li et al Biotechnol Bioeng. 2019 Feb 10. doi: 10.

Insert

Apobec1, Casp nickase, UG1-sgRNA

Expression

Bacterial

Promoter

Ptm

Available since

Jan. 23, 2019

Availability

Academic Institutions and Nonprofits only

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pTaU6-esgRNA

Plasmid

#115630

Purpose

expression esgRNA in wheat protoplasts

Depositor

Caixia Gao

Publication

Li et al Genome Biol. 2018 May 29;19(1):59. doi:

Insert

TaU6p-esgRNA

Use

CRISPR

Available since

Jan. 22, 2019

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(-)-ABE7.10

Plasmid

#120399

Purpose

Expresses ABE7.10 in mammalian cells

Depositor

Junjiu Huang

Publication

Liang et al Nat Commun. 2019 Jan 8;10(1):67. doi: 10

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

ABE7.10

Expression

Mammalian

Mutation

Mammalian codon-optimized

Promoter

CMV

Available since

Jan. 16, 2019

Availability

Academic Institutions and Nonprofits only

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pCMV-hA3A-eBE-Y132D

Plasmid

#113429

Purpose

Expresses hA3A-eBE-Y132D in mammalian cells

Depositor

Jia Chen

Publication

Wang et al Nat Biotechnol. 2018 Aug 20. pii: nbt.41

Has service

50 µg Transfection-Ready DNA and 100 µg Transfection-Ready DNA

Insert

hA3A-eBE-Y132D (APOBEC3A S. pyogenes and Bacteriophage PBS2, Human)

Use

CRISPR

Expression

Mammalian

Mutation

hAPOBEC3A_Y132D

Promoter

CMV

Available since

Aug. 21, 2018

Availability

Academic Institutions and Nonprofits only

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