162,199 results

1. pCMV_BE4max

   Plasmid

   #112093

   Purpose

   C:G-to-T:A base editing

   Depositor

   David Liu

   Article

   Koblan et al Nat Biotechnol. 2018 May 29. pii: nbt.41

   Insert

   BE4max
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   June 26, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pBacMam2-DiEx-LIC-C-flag_huntingtin_full-length_Q109

   Plasmid

   #111730

   Purpose

   Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

   Depositor

   Cheryl Arrowsmith

   Article

   Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expression

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q109 (polyQ repeat)

   Promoter

   CMV and P10

   Available since

   Oct. 31, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. Il12b 400bp pro-Luc

   Plasmid

   #20020

   Depositor

   Stephen Smale

   Article

   Plevy et al Mol Cell Biol. 1997 Aug . 17(8):4572-88.

   Insert

   Il12b promoter (Il12b Mouse)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Jan. 28, 2009

   Availability

   Academic Institutions and Nonprofits only

   

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4. GFP-CaM-NanoLuc-15aa-uTEVp

   Plasmid

   #163034

   Purpose

   FLiCRE protease with luciferin-gating for neuronal expression

   Depositor

   Alice Ting

   Article

   Kim et al Cell. 2020 Dec 23;183(7):2003-2019.e16.

   Insert

   GFP-CaM-NanoLuc-15aa-uTEVp
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Synapsin

   Available since

   Jan. 7, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. AiP12211 - pAAV-AiE0050m_3xC2-minCMV-SYFP2-WPRE3-BGHpA (Alias: CN2211)

   Plasmid

   #223974

   Purpose

   AiE0050m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in cortical L4/5_IT neurons

   Depositor

   The Allen Institute for Brain Science, Jonathan Ting

   Article

   Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

   Insert

   SYFP2
   

   Use

   AAV

   Tags

   Expression

   Mutation

   NA

   Promoter

   minBG

   Available since

   Feb. 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV-FLEX-DTR-GFP

   Plasmid

   #124364

   Purpose

   conditional expression of a diphtheria toxin receptor (DTR)–GFP fusion protein

   Depositor

   Eiman Azim, Thomas Jessell

   Article

   Azim et al Nature. 2014 Apr 17;508(7496):357-63. do

   Has Service

   AAV2

   Insert

   DTR-GFP
   

   Use

   AAV

   Tags

   GFP

   Expression

   Mutation

   Promoter

   Chicken B-actin

   Available since

   Oct. 7, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCAGGS-PHFF-sh-hBVRA

   Plasmid

   #100285

   Purpose

   Expression vector for phycocyanobilin (PCB) synthesis and shRNA for human BVRA gene in mammalian cells

   Depositor

   Kazuhiro Aoki

   Article

   Uda et al Proc Natl Acad Sci U S A. 2017 Oct 24. p

   Inserts

   MTS-PcyA-FLAG-P2A-MTS-HA-HO1-P2A-MTS-Myc-Fd-P2A-MTS-Fnr-T7 (synthetic genes)
   shRNA for human BVRA
   

   Use

   Tags

   FLAG, T7 and Mitochondria-targeting sequence (MTS…

   Expression

   Mammalian

   Mutation

   All genes are codon-optimized for expression in h…

   Promoter

   CAG promoter and H1 promoter

   Available since

   Sept. 20, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. IL-4 promoter luciferase

   Plasmid

   #12195

   Depositor

   Anjana Rao

   Article

   Macian et al EMBO J. 2000 Sep 1. 19(17):4783-95.

   Insert

   IL-4 promoter (Il4 Mouse)
   

   Use

   Luciferase

   Tags

   luciferase

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   July 20, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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9. R777-E285 Hs.ROCK2

   Plasmid

   #70569

   Purpose

   Gateway ORF clone of human ROCK2 [NM_004850.3] with stop codon (for native or N-terminal fusions)

   Depositor

   Dominic Esposito

   Insert

   ROCK2 (ROCK2 Human)
   

   Use

   Gateway entry clone

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 1, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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10. pHPHS232

    Plasmid

    #228356

    Purpose

    Landing pad with Bxb1 attP_wildtype site, Dox-inducible BFP-iCasp9-Blasticidin, CMV-driven rtTA3, T2A-neomycin for HDR into AAVS1 locus

    Depositor

    Arvind Rasi Subramaniam

    Article

    Nugent et al bioRxiv [Preprint]. 2024 Jul 26:2024.07.

    Inserts

    mTagBFP2
    Reverse tetracycline transactivator 3
    neo
    

    Use

    Tags

    Blasticidin S deaminase and iCasp9

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3GV and gene trap

    Available since

    Jan. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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