We narrowed to 11,284 results for: Vars;

1. pcDNA3-sACE2v6-Fc(IgA1)

   Plasmid

   #145161

   Purpose

   Mammalian expression plasmid for soluble ACE2-Fc fusion (IgA1) high affinity variant 6

   Depositor

   Erik Procko

   Article

   Chan et al Science. 2020 Sep 4;369(6508):1261-1265.

   Insert

   Angiotensin-converting enzyme 2 (ACE2 Human)
   

   Tags

   Fc region of human IgA1

   Expression

   Mammalian

   Mutation

   Extracellular, soluble protease domain (a.a. M1-D…

   Promoter

   CMV

   Available Since

   April 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. BAP1-010

   Plasmid

   #68366

   Purpose

   stable expression of BAP1 delta 221-238 in mammalian cells

   Depositor

   Emanuela Felley-Bosco, Rolf Stahel

   Article

   Parrotta et al J Thorac Oncol. 2017 Apr 4. pii: S1556-0

   Insert

   BAP1 (BAP1 Human)
   

   Expression

   Mammalian

   Mutation

   delta 221-238, splice variant found in human meso…

   Promoter

   CMV

   Available Since

   April 12, 2017

   Availability

   Academic Institutions and Nonprofits only

3. FLAG-YAP2 (8SA)-pcw107

   Plasmid

   #64637

   Purpose

   when used to produce lentivirus, express physiological levels of insert

   Depositor

   David Sabatini, Kris Wood

   Article

   Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

   Insert

   YAP2 (transcript variant 3) (YAP1 Human)
   

   Use

   Lentiviral

   Tags

   FLAG

   Mutation

   8SA*

   Promoter

   PGK

   Available Since

   Dec. 8, 2015

   Availability

   Academic Institutions and Nonprofits only

4. R620-M06-303: CMV51p> TPAss-SARS-CoV-2 S-RBD(319-529)-3C-His8-SBP K417N/E484K/N501Y

   Plasmid

   #170192

   Purpose

   Mammalian expression of SARS-CoV-2 spike receptor-binding domain (RBD), triple mutant from B.1.351 variant

   Depositor

   Dominic Esposito

   Article

   Mehalko et al Protein Expr Purif. 2021 Mar;179:105802.

   Insert

   SARS-CoV-2 RBD (S SARS-CoV-2)
   

   Tags

   3C-His8-SBP

   Expression

   Mammalian

   Mutation

   K417N, E484K, N501Y

   Promoter

   CMV51

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. R620-M04-303: CMV51p> TPAss-SARS-CoV-2 S-RBD(318-529)-3C-His8-SBP N501Y

   Plasmid

   #170190

   Purpose

   ammalian expression of SARS-CoV-2 spike receptor-binding domain (RBD), N501Y mutant from B.1.1.7 variant

   Depositor

   Dominic Esposito

   Article

   Mehalko et al Protein Expr Purif. 2021 Mar;179:105802.

   Insert

   SARS-CoV-2 RBD (S SARS-CoV-2)
   

   Tags

   3C-His8-SBP

   Expression

   Mammalian

   Mutation

   N501Y

   Promoter

   CMV51

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pU6-crRNA(SOD1)

   Plasmid

   #109321

   Purpose

   AAV vector expressing crRNA for AsCpf1 (RR variant) targeting human SOD1

   Depositor

   Feng Zhang

   Article

   Tekin et al Nat Biomed Eng. 2018 Jul;2(7):540-554. d

   Insert

   mCherry-KASH (SOD1 Human)
   

   Use

   AAV

   Promoter

   hSyn1

   Available Since

   April 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. R620-M01-303: CMV51p> SARS-CoV-2 S(1-1208)-2P-T4f-3C-His8-Strep2x2 B.1.1.7

   Plasmid

   #170188

   Purpose

   Mammalian expression of SARS-CoV-2 soluble spike trimer protein (B.1.1.7 variant)

   Depositor

   Dominic Esposito

   Article

   Esposito et al Protein Expr Purif. 2020 Jun 4;174:10568

   Insert

   SARS-CoV-2 S (spike) B.1.1.7 (S SARS-CoV-2)
   

   Tags

   3C-His8-Strep2x2

   Expression

   Mammalian

   Mutation

   Δ(69-70), Δ144, N501Y, A570D, D614G, P681H, T716I…

   Promoter

   CMV51

   Available Since

   Nov. 16, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. Fibronectin-human-mutated V1 O-Glycosylation site

   Plasmid

   #120406

   Purpose

   enables eukaryotic expression of human plasma fibronectin in which the third O-glycosylation site was mutated from threonine to serine

   Depositor

   Inaam Nakchbandi

   Article

   Sens et al J Bone Miner Res. 2017 Jan;32(1):70-81.

   Insert

   Fibronectin (FN1 Human)
   

   Expression

   Mammalian

   Mutation

   Contains complete variable region with a mutation…

   Promoter

   CMV

   Available Since

   Jan. 23, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. Fibronectin-human-mutated N-terminal (N), V1 and V2 Glycosylation sites

   Plasmid

   #120407

   Purpose

   enables eukaryotic expression of human plasma fibronectin in which all three O-glycosylation sites were mutated from threonine to serine

   Depositor

   Inaam Nakchbandi

   Article

   Sens et al J Bone Miner Res. 2017 Jan;32(1):70-81.

   Insert

   Fibronectin (FN1 Human)
   

   Expression

   Mammalian

   Mutation

   Contains complete variable region with mutations …

   Promoter

   CMV

   Available Since

   Jan. 23, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pSGEM hKCNQ1

    Plasmid

    #219952

    Purpose

    Expresses human KCNQ1 in Xenopus laevis oocytes

    Depositor

    Niels Decher

    Article

    Kiper et al Proc Natl Acad Sci U S A. 2024 Jun 18;12

    Insert

    KCNQ1 (KCNQ1 Human)
    

    Use

    Xenopus laevis expression

    Mutation

    contains silent sequence variations

    Available Since

    Aug. 13, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. hKCNQ1 pCDNA3.1(-)

    Plasmid

    #219953

    Purpose

    Expresses human KCNQ1 in mammalian cells

    Depositor

    Niels Decher

    Article

    Kiper et al Proc Natl Acad Sci U S A. 2024 Jun 18;12

    Insert

    KCNQ1 (KCNQ1 Human)
    

    Expression

    Mammalian

    Mutation

    contains silent sequence variations

    Promoter

    CMV

    Available Since

    Aug. 13, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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12. pcDNA3.1(+)_Nav1.6(K1425TAG, Y371C)-HA

    Plasmid

    #239766

    Purpose

    Expresses TTX-resistant (Y371C) variant of mouse Nav1.6 with a TAG codon at position 1425 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    K1425TAG, Y371C

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pcDNA3.1(+)_Nav1.6(K1546TAG, Y371C)-HA

    Plasmid

    #239767

    Purpose

    Expresses TTX-resistant (Y371C) variant of mouse Nav1.6 with a TAG codon at position 1546 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    K1546TAG, Y371C

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3.1(+)_Nav1.6(K1425TAG, Y371C)-P2A-eGFP

    Plasmid

    #239769

    Purpose

    Expresses independantly TTX-resistant (Y371C) variant of mouse Nav1.6 with a TAG codon at position 1425 and eGFP in mammalian cells.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Expression

    Mammalian

    Mutation

    K1435TAG, Y371C

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pcDNA3.1(+)_Nav1.6(K1425TAG, Y371C, I1652N)-HA

    Plasmid

    #239770

    Purpose

    Expresses pathogenic (I1652N) TTX-resistant variant of mouse Nav1.6 with a TAG codon at position 1425 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    K1425TAG, Y371C, I1652N

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pcDNA3.1(+)_Nav1.6(K1546TAG, Y371C , I1652N)-HA

    Plasmid

    #239771

    Purpose

    Expresses pathogenic (I1652N) TTX-resistant variant of mouse Nav1.6 with a TAG codon at position 1546 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    I1652N, Y371C, K1546TAG

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pcDNA3.1(+)_Nav1.6(K1425TAG, Y371C, T1785P)-HA

    Plasmid

    #239772

    Purpose

    Expresses pathogenic (T1785P) TTX-resistant variant of mouse Nav1.6 with a TAG codon at position 1425 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    K1425TAG, Y371C, T1785P,

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pcDNA3.1(+)_Nav1.6(K1546TAG, Y371C , T1785P)-HA

    Plasmid

    #239773

    Purpose

    Expresses pathogenic (T1785P) TTX-resistant variant of mouse Nav1.6 with a TAG codon at position 1546 and a C-terminal HA tag in mammalian cells. Can be used for click labeling.

    Depositor

    Ivana Nikić-Spiegel

    Article

    Stajkovic et al J Cell Sci. 2023 Jun 15;136(12):jcs26060

    Insert

    Scn8a (Scn8a Mouse)
    

    Tags

    HA-tag

    Expression

    Mammalian

    Mutation

    K1546TAG, Y371C, T1785P

    Promoter

    CMV

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. AAVS1-SA-CAG-Pa01-BFP

    Plasmid

    #234142

    Purpose

    Perturb Seq landing pad with Pa01 recombinase at the AAVS1 loci

    Depositor

    Gary Hon

    Article

    Sivakumar et al bioRxiv [Preprint]. 2025 Jan 23:2025.01.

    Insert

    Pa01
    

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. GFP Cav2.2 human HAgHA-plus exon 18a - Short-Cterm - Arginine -in pcDNA3

    Plasmid

    #198915

    Purpose

    N-terminal GFP tagged, exofacial HAgHA tag in Domain II, contains exon 18a, Short form of alternatively spliced C-teminus, SNP rs2278973 variant Arginine, in pcDNA3 vector

    Depositor

    Annette Dolphin

    Article

    Dahimene et al Function (Oxf). 2023 Oct 19;5(1):zqad060

    Insert

    Cav2.2 (CACNA1B Human)
    

    Tags

    N-terminal GFP, internal double HA

    Expression

    Mammalian

    Mutation

    snp rs2278973 Arginine

    Promoter

    CMV

    Available Since

    April 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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21. pAAV-CAG-iGluSnFR4s-PDGFR-WPRE

    Plasmid

    #234449

    Purpose

    AAV-mediated expression of glutamate sensor with improved sensitivity and slow deactivation kinetics (4s = slow); NGR vector matches or outperforms PDGFR in all conditions tested.

    Depositor

    GENIE Project

    Article

    Aggarwal et al bioRxiv 2025.03.20.643984

    Insert

    iGluSnFR4s-PDGFR
    

    Use

    AAV

    Tags

    IgK chain and Myc epi tag-PDGFR TM Domain

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    March 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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22. pTwist-SARS-CoV-2 Spike-deltaC18 XBB.1.16 F456L

    Plasmid

    #212455

    Purpose

    Encodes SARS-CoV-2 variant XBB.1.16 Spike F456L for pseudovirus production

    Depositor

    Alejandro Balazs

    Article

    Roederer et al medRxiv [Preprint]. 2024 Mar 7:2024.03.0

    Insert

    SARS-CoV-2 Spike XBB.1.16 F456L (S Severe acute respiratory syndrome coronavirus 2)
    

    Expression

    Mammalian

    Mutation

    See Depositor Comments.

    Promoter

    CAG

    Available Since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. Click editor utilizing mSA for template recruitment and ePhi29 DNA polymerase - pCMV-T7-mSA-nCas9-ePhi29 (JO1398)

    Plasmid

    #217803

    Purpose

    Variant CE1 construct with mSA for template recruitment and ePhi29(D169A) DNA pol, expressed from CMV or T7 promoters.

    Depositor

    Benjamin Kleinstiver

    Article

    Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

    Insert

    mSA-linker-SV40NLS-nSpCas9-BPNLS-ePhi29-BPNLS
    

    Use

    CRISPR; In vitro transcription; t7 promoter

    Tags

    BPNLS

    Expression

    Mammalian

    Mutation

    nSpCas9(H840A); Phi29(D169A/M8R/V51A/M97T/G197D/E…

    Promoter

    CMV and T7

    Available Since

    Sept. 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. Click editor utilizing Cdc13 for template recruitment - pCMV-T7-Cdc13-nCas9-EcKlenow (JO1293)

    Plasmid

    #217796

    Purpose

    Variant CE1 construct with Cdc13 telomere binding protein for template recruitment, expressed from CMV or T7 promoters.

    Depositor

    Benjamin Kleinstiver

    Article

    Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

    Insert

    Cdc13-XTEN-nSpCas9-BPNLS-EcKlenow(-exo)-BPNLS
    

    Use

    CRISPR; In vitro transcription; t7 promoter

    Tags

    BPNLS

    Expression

    Mammalian

    Mutation

    nSpCas9(H840A); EcKlenow(-exo;D355A/E357A)

    Promoter

    CMV and T7

    Available Since

    Sept. 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. Click editor utilizing Cdc13(Y556A) for template recruitment - pCMV-T7-Cdc13(Y556A)-nCas9-EcKlenow (JO1329)

    Plasmid

    #217797

    Purpose

    Variant CE1 construct with Cdc13(Y556A) telomere binding protein for template recruitment, expressed from CMV or T7 promoters.

    Depositor

    Benjamin Kleinstiver

    Article

    Ferreira da Silva et al Nat Biotechnol. 2024 Jul 22. doi: 10.103

    Insert

    Cdc13(Y556A)-XTEN-nSpCas9-BPNLS-EcKlenow(-exo)-BPNLS
    

    Use

    CRISPR; In vitro transcription; t7 promoter

    Tags

    BPNLS

    Expression

    Mammalian

    Mutation

    Cdc13(Y556A); nSpCas9(H840A); EcKlenow(-exo;D355A…

    Promoter

    CMV and T7

    Available Since

    Sept. 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pMRX-IP-muGFP-hATG2A mLIRΔWIR

    Plasmid

    #215508

    Purpose

    Expresses GFP tagged human ATG2A which has the mutation in LC3 interacting region and lacks WIPI interacting region.

    Depositor

    Noboru Mizushima

    Article

    Shimizu et al Hum Mol Genet. 2023 Aug 7;32(16):2623-26

    Insert

    Autophagy related 2A (ATG2A Human)
    

    Use

    Retroviral

    Tags

    muGFP

    Expression

    Mammalian

    Mutation

    P656R (natural variant with no functional relevan…

    Available Since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. TR01F/hFGFR3-G380R-V5

    Plasmid

    #214908

    Purpose

    for PiggyBac mediated integration and stable expression of hFGFR3-G380R variant that is associated with Achondroplasia

    Depositor

    Pavel Krejčí

    Article

    Kimura et al Sci Transl Med. 2021 May 5;13(592):eaba4

    Insert

    FGFR3 (FGFR3 Human)
    

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    G380R substitution

    Promoter

    truncated CMV promoter

    Available Since

    April 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pCDH-V1-rCD20-BSD

    Plasmid

    #209752

    Purpose

    To reconstitute CD20 expression with a specific mRNA isoform (variant 1) after CRISPR-Cas9-mediated knockout of CD20.

    Depositor

    Andrei Thomas-Tikhonenko

    Article

    Ang et al Blood. 2023 Sep 8:blood.2023020400. doi:

    Insert

    MS4A1 (MS4A1 Human)
    

    Use

    Lentiviral

    Mutation

    The CCTGGGGGGTCTTCTGATGATCC sequence within the C…

    Available Since

    Nov. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pCDH-V2-rCD20-BSD

    Plasmid

    #209753

    Purpose

    To reconstitute CD20 expression with a specific mRNA isoform (variant 2) after CRISPR-Cas9-mediated knockout of CD20.

    Depositor

    Andrei Thomas-Tikhonenko

    Article

    Ang et al Blood. 2023 Sep 8:blood.2023020400. doi:

    Insert

    MS4A1 (MS4A1 Human)
    

    Use

    Lentiviral

    Mutation

    The CCTGGGGGGTCTTCTGATGATCC sequence within the C…

    Available Since

    Nov. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pCDH-V3-rCD20-BSD

    Plasmid

    #209754

    Purpose

    To reconstitute CD20 expression with a specific mRNA isoform (variant 3) after CRISPR-Cas9-mediated knockout of CD20.

    Depositor

    Andrei Thomas-Tikhonenko

    Article

    Ang et al Blood. 2023 Sep 8:blood.2023020400. doi:

    Insert

    MS4A1 (MS4A1 Human)
    

    Use

    Lentiviral

    Mutation

    The CCTGGGGGGTCTTCTGATGATCC sequence within the C…

    Available Since

    Nov. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge