We narrowed to 80 results for: SHP2

1. pLX307/PTPN11 T73I

   Plasmid

   #140939

   Purpose

   expresses PTPN11 T73I

   Depositor

   Kimberly Stegmaier

   Article

   Cremer et al Cancer Discov. 2020 Feb;10(2):214-231. d

   Insert

   PTPN11 protein tyrosine phosphatase non-receptor type 11 [ Homo sapiens (human) ] (PTPN11 Human)
   

   Use

   Tags

   V5

   Expression

   Mammalian

   Mutation

   T73I

   Promoter

   EF1a

   Available since

   June 4, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLX307/PTPN11 E76G

   Plasmid

   #140862

   Purpose

   expresses PTPN11 E76G

   Depositor

   Kimberly Stegmaier

   Article

   Cremer et al Cancer Discov. 2020 Feb;10(2):214-231. d

   Insert

   PTPN11 protein tyrosine phosphatase non-receptor type 11 [ Homo sapiens (human) ] (PTPN11 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   E76G

   Promoter

   EF1a

   Available since

   June 4, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pGEX-6p-2-GST-PD-1icd (AA194-288, Y223F, Y248F)

   Plasmid

   #180815

   Purpose

   Expression of GST fused human PD-1 intracellular domain (AA194-288, Y223F, Y248F)

   Depositor

   Enfu Hui

   Article

   Xu et al J Cell Biol. 2020 Jun 1;219(6). pii: 151

   Insert

   PD-1int (AA194-288, Y223F, Y248F) (PDCD1 Human)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   PD-1 (Y223F, Y248F)

   Promoter

   Tac

   Available since

   March 14, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pHR-SV40-BTLAecto&tmd-PD-1icd-mGFP

   Plasmid

   #180795

   Purpose

   Expression of human BTLA extracellular domain and transmembrane domain fused to PD-1 intracellular domain followed by mEGFP

   Depositor

   Enfu Hui

   Article

   Xu et al J Cell Biol. 2020 Jun 1;219(6). pii: 151

   Insert

   BTLAecto&tm-PD-1int (BTLA, PDCD1 Human)
   

   Use

   Lentiviral

   Tags

   mEGFP

   Expression

   Mutation

   Promoter

   SV40

   Available since

   March 14, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. PTPN11 in pENTR

   Plasmid

   #216604

   Purpose

   gateway cloning donor vector containing PTPN11

   Depositor

   Douglas Allan, Christopher Loewen

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   Gateway entry plasmid

   Tags

   Expression

   Mutation

   Promoter

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. PTPN11

   Plasmid

   #38965

   Purpose

   Bacterial expression for structure determination; may not be full ORF

   Depositor

   Nicola Burgess-Brown

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   Tags

   His Tev

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   March 18, 2013

   Availability

   Academic Institutions and Nonprofits only

7. pSicoR-PTPN11i1

   Plasmid

   #59612

   Purpose

   Expression of shRNA against human PTPN11

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

8. pSicoR-PTPN11i2

   Plasmid

   #59613

   Purpose

   Expression of shRNA against human PTPN11

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   PTPN11 (PTPN11 Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

9. FRB-GFP-Gab1(Y628F/Y660F)

   Plasmid

   #188658

   Purpose

   FRB coupled to GFP tagged Gab1 with Shp2 binding sites mutated to Phe

   Depositor

   Andrei Karginov

   Article

   Fauser et al J Cell Biol. 2022 Aug 1;221(8). pii: 213

   Insert

   GRB associated binding protein 1 (Gab1 Mouse)
   

   Use

   Tags

   FRB and GFP

   Expression

   Mammalian

   Mutation

   Y628F and Y660F

   Promoter

   CMV

   Available since

   Aug. 19, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. FRB-GFP-Gab2(Y604F/Y634F)

    Plasmid

    #188659

    Purpose

    FRB coupled to GFP tagged Gab2 with Shp2 binding sites mutated to Phe

    Depositor

    Andrei Karginov

    Article

    Fauser et al J Cell Biol. 2022 Aug 1;221(8). pii: 213

    Insert

    GRB associated binding protein 2 (Gab2 Mouse)
    

    Use

    Tags

    FRB and GFP

    Expression

    Mammalian

    Mutation

    Y604F and Y634F

    Promoter

    CMV

    Available since

    Aug. 19, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pHAGE-PTPN11

    Plasmid

    #116782

    Purpose

    Lentiviral expression of PTPN11

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    WT

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pHAGE-PTPN11-Q79R

    Plasmid

    #116646

    Purpose

    Lentiviral expression of PTPN11 Q79R

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Q79R

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pHAGE-PTPN11-E76Q

    Plasmid

    #116642

    Purpose

    Lentiviral expression of PTPN11 E76Q

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    E76Q

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pHAGE-PTPN11-G60R

    Plasmid

    #116643

    Purpose

    Lentiviral expression of PTPN11 G60R

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    G60R

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pHAGE-PTPN11-E139D

    Plasmid

    #116640

    Purpose

    Lentiviral expression of PTPN11 E139D

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    E139D

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pHAGE-PTPN11-T73I

    Plasmid

    #116647

    Purpose

    Lentiviral expression of PTPN11 T73I

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    T73I

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pHAGE-PTPN11-N58K

    Plasmid

    #116645

    Purpose

    Lentiviral expression of PTPN11 N58K

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    N58K

    Promoter

    Available since

    April 9, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pHAGE-PTPN11-E69K

    Plasmid

    #116641

    Purpose

    Lentiviral expression of PTPN11 E69K

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    E69K

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pHAGE-PTPN11-N308D

    Plasmid

    #116644

    Purpose

    Lentiviral expression of PTPN11 N308D

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    N308D

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pHAGE-PTPN11-V51A

    Plasmid

    #116648

    Purpose

    Lentiviral expression of PTPN11 V51A

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    V51A

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge