We narrowed to 524 results for: hyper

1. HypaCas9

   Plasmid

   #138557

   Purpose

   Expresses human codon-optimized hyper-accurate SpCas9 and blasticidin resistance: EFS promoter-HypaCas9-NLS-FLAG-P2A-BSD

   Depositor

   Hyongbum Kim

   Article

   Kim et al Nat Biotechnol. 2020 Nov;38(11):1328-133

   Insert

   HypaCas9
   

   Use

   CRISPR and Lentiviral

   Tags

   BSD, FLAG, and NLS

   Expression

   Mammalian

   Mutation

   N692A, M694A, Q695A, H698A

   Promoter

   EFS

   Available since

   June 9, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSLQ10844

   Plasmid

   #183956

   Purpose

   CAG-hyperdCas12a-HA-miniVPR-mCherry-T2A-HygroR

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Insert

   HyperdCas12a
   

   Use

   CRISPR

   Tags

   HA, Hygromycin Resistance, and mCherry

   Expression

   Mammalian

   Mutation

   D832A, D156R, E292R, D235R, D350R

   Promoter

   CAG

   Available since

   May 31, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pSLQ10704

   Plasmid

   #183957

   Purpose

   U6-SKSKSO(crRNA array)-EF1a-PuroR-T2A-BFP

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Insert

   SKSKSO array
   

   Use

   Lentiviral

   Tags

   EF1a-Puro-T2A-TagBFP

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Aug. 17, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pSLQ10875

   Plasmid

   #183963

   Purpose

   CBA-hyperdCas12a-HA-KRAB-mCherry

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Insert

   HyperdCas12a
   

   Use

   CRISPR

   Tags

   HA, KRAB, and mCherry

   Expression

   Mammalian

   Mutation

   D832A, D156R, E292R, D235R, D350R

   Promoter

   CBA

   Available since

   June 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pSLQ10871

   Plasmid

   #183962

   Purpose

   U6-SKSKSO(crRNA array)-CAG-dCas12a(WT)-miniVPR

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Inserts

   dCas12a(wildtype)
   poly-crRNA array targeting Sox2-Klf4-Oct4
   

   Use

   CRISPR

   Tags

   HA

   Expression

   Mammalian

   Mutation

   D832A

   Promoter

   CAG and U6

   Available since

   June 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pSLQ10333

   Plasmid

   #183955

   Purpose

   CAG-dCas12a(WT)-HA-miniVPR-mCherry-T2A-HygroR

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Insert

   Nuclease-dead Lb Cas12a
   

   Use

   CRISPR

   Tags

   HA, Hygromycin Resistance, and mCherry

   Expression

   Mammalian

   Mutation

   D832A

   Promoter

   CAG

   Available since

   May 31, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pSLQ10715

   Plasmid

   #183960

   Purpose

   U6-crOct4-CAG-hyperdCas12a-miniVPR

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Inserts

   HyperdCas12a
   crRNA targeting Oct4
   

   Use

   CRISPR

   Tags

   HA

   Expression

   Mammalian

   Mutation

   D832A, D156R, E292R, D235R, D350R

   Promoter

   CAG and U6

   Available since

   June 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLV.EF1α.mEmerald.CD9.miR9T

   Plasmid

   #170452

   Purpose

   Lentiviral plasmid that encodes mEmerald-CD9 fusion protein with microRNA 9 tandem cassette to restrict expression to microglia with EF1-alpha promoter.

   Depositor

   Tsuneya Ikezu

   Article

   Clayton et al Mol Neurodegener. 2021 Mar 22;16(1):18.

   Insert

   CD9 (CD9 Human)
   

   Use

   Lentiviral

   Tags

   mEmerald

   Expression

   Mutation

   Promoter

   EF1a

   Available since

   May 27, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pSLQ10713

   Plasmid

   #183958

   Purpose

   U6-crSox2-CAG-hyperdCas12a-miniVPR

   Depositor

   Stanley Qi

   Article

   Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

   Inserts

   HyperdCas12a
   crRNA targeting Sox2
   

   Use

   CRISPR

   Tags

   HA

   Expression

   Mammalian

   Mutation

   D832A, D156R, E292R, D235R, D350R

   Promoter

   CAG and U6

   Available since

   June 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. crTet in pSLQ8453

    Plasmid

    #183965

    Purpose

    U6-crTet-EF1a-Puro-T2A-BFP-WPRE

    Depositor

    Stanley Qi

    Article

    Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

    Insert

    crTet
    

    Use

    Lentiviral

    Tags

    EF1a-Puro-T2A-BFP

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pSLQ10714

    Plasmid

    #183959

    Purpose

    U6-crKlf4-CAG-hyperdCas12a-miniVPR

    Depositor

    Stanley Qi

    Article

    Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

    Inserts

    HyperdCas12a
    crRNA targeting Klf4
    

    Use

    CRISPR

    Tags

    HA

    Expression

    Mammalian

    Mutation

    D832A, D156R, E292R, D235R, D350R

    Promoter

    CAG and U6

    Available since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pSLQ10878

    Plasmid

    #183964

    Purpose

    CAG-hyperCas12a(nuclease active)-HA-P2A-mCherry-T2A-HygroR

    Depositor

    Stanley Qi

    Article

    Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

    Insert

    HyperdCas12a
    

    Use

    CRISPR

    Tags

    HA, Hygromycin Resistance, and mCherry

    Expression

    Mammalian

    Mutation

    D156R, E292R, D235R, D350R

    Promoter

    CAG

    Available since

    June 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pSLQ10873

    Plasmid

    #183961

    Purpose

    U6-SKSKSO(crRNA array)-CAG-hyperdCas12a-HA-miniVPR

    Depositor

    Stanley Qi

    Article

    Guo et al Nat Cell Biol. 2022 Apr;24(4):590-600. d

    Inserts

    HyperdCas12a
    poly-crRNA array targeting Sox2-Klf4-Oct4
    

    Use

    CRISPR

    Tags

    HA

    Expression

    Mammalian

    Mutation

    D832A, D156R, E292R, D235R, D350R

    Promoter

    CAG and U6

    Available since

    Aug. 17, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pGL004

    Plasmid

    #215336

    Purpose

    amyE integration vector for IPTG-inducible expression in Bacillus subtilis (Pspank-Hy promoter)

    Depositor

    Gene-Wei Li

    Type

    Empty backbone

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    hyper-pSpank

    Available since

    March 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pEGFP Tubulin K40Q

    Plasmid

    #105302

    Purpose

    To study effects of acetyl-mimetic (hyper-acetylated) tubulin

    Depositor

    Kenneth Yamada

    Article

    Joo et al Nat Commun. 2014 Mar 25;5:3510. doi: 10.

    Insert

    alpha tubulin (TUBA1B Human)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    K40Q

    Promoter

    Available since

    Feb. 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pC1-PIP-SHOW

    Plasmid

    #42212

    Purpose

    Genetically encoded fluorescent indicator for simultaneous PIP3 and hydrogen peroxide detection.

    Depositor

    Vsevolod Belousov

    Article

    Mishina et al Antioxid Redox Signal. 2012 Aug 1;17(3):

    Insert

    PIP-SHOW
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Dec. 6, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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17. pMXs-EGFP-Rheb-HVR HRas-IP

    Plasmid

    #13833

    Depositor

    Shinya Yamanaka

    Article

    Takahashi et al J Biol Chem. 2005 Sep 23. 280(38):32768-

    Insert

    Rheb-HVR HRas (Rheb Mouse)
    

    Use

    Retroviral

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    N-terminal of Rheb and hyper variable region (HVR…

    Promoter

    Available since

    March 16, 2007

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-SypHer2-DAAO-NES

    Plasmid

    #119184

    Purpose

    Fusion of the pH-sensitive fluorescent biosensor SypHer2 with D-amino acid oxidase; excluded from nucleus. CMV promoter. Can serve as a pH control for HyPer.

    Depositor

    Thomas Michel

    Article

    Steinhorn et al Nat Commun. 2018 Oct 2;9(1):4044. doi: 1

    Insert

    SypHer2-DAAO-NES
    

    Use

    AAV

    Tags

    NES

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Nov. 29, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV_CaMKII-TRPV1-flag

    Plasmid

    #238924

    Purpose

    Expression of the human TRPV1 channel with a Flag-tag in excitatory neurons

    Depositor

    Vsevolod Belousov

    Article

    Maltsev et al Cell Mol Life Sci. 2024 Oct 25;81(1):437

    Insert

    CaMKII-TRPV1-flag
    

    Use

    AAV

    Tags

    flag

    Expression

    Mammalian

    Mutation

    Promoter

    CaMKIIalfa

    Available since

    Aug. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pXcX-PRS-EGFP

    Plasmid

    #25865

    Depositor

    Sergey Kasparov

    Article

    Teschemacher et al Hypertension. 2008 Aug . 52(2):351-8.

    Insert

    PRS driven enhanced green fluorescent protein
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 30, 2010

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge