We narrowed to 6,529 results for: human c myc

1. Halo-LC3B HRD

   Plasmid

   #207539

   Purpose

   Homologous recombination donor to integrate a 3xFLAG-HaloTag at the endogenous LC3B locus in human cells

   Depositor

   Jens Schmidt

   Article

   Broadbent et al J Cell Biol. 2023 Jul 3;222(7):e20221007

   Insert

   HaloTag with internal PuroR cassette flanked by human LC3B locus sequences
   

   Use

   Tags

   HaloTag

   Expression

   Mammalian

   Mutation

   Promoter

   Endogenous

   Available since

   April 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLP-LNCX-PIK3CA-W11STOP

   Plasmid

   #25634

   Depositor

   Todd Waldman

   Article

   Kim et al Mol Cell Biol. 2007 Jan . 27(2):662-77.

   Insert

   PIK3CA (PIK3CA Human)
   

   Use

   Retroviral

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   June 21, 2010

   Availability

   Academic Institutions and Nonprofits only

3. pHPHS232

   Plasmid

   #228356

   Purpose

   Landing pad with Bxb1 attP_wildtype site, Dox-inducible BFP-iCasp9-Blasticidin, CMV-driven rtTA3, T2A-neomycin for HDR into AAVS1 locus

   Depositor

   Arvind Rasi Subramaniam

   Article

   Nugent et al bioRxiv [Preprint]. 2024 Jul 26:2024.07.

   Inserts

   mTagBFP2
   Reverse tetracycline transactivator 3
   neo
   

   Use

   Tags

   Blasticidin S deaminase and iCasp9

   Expression

   Mammalian

   Mutation

   Promoter

   TRE3GV and gene trap

   Available since

   Jan. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. lentiMutB3GNT5-blast

   Plasmid

   #208380

   Purpose

   lentiviral vector for expressing human B3GNT5 with C-terminal myc-DDK tag, includes nucleotide change in PAM targeting sequence

   Depositor

   Jennifer Kohler

   Insert

   Beta-1,3-N-Acetylglucosaminyltransferase 5 (B3GNT5 Human)
   

   Use

   Lentiviral

   Tags

   myc, FLAG

   Expression

   Mammalian

   Mutation

   nt 922 c->g (PAM site inactivation)

   Promoter

   EF-1 alpha core promoter

   Available since

   Sept. 3, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLM-vexGFP-Oct4

   Plasmid

   #22240

   Purpose

   2nd generation lentiviral vector

   Depositor

   Michel Sadelain

   Article

   Papapetrou et al Proc Natl Acad Sci U S A. 2009 Aug 4. 10

   Insert

   vexGFP_2A_OCT4 (POU5F1 Human, synthetic fluorescent protein)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Feb. 5, 2010

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGL2-Mcl-1

   Plasmid

   #19132

   Depositor

   Wafik El-Deiry

   Article

   Ricci et al Cancer Cell. 2007 Jul . 12(1):66-80.

   Insert

   Mcl-1 promoter (MCL1 Human)
   

   Use

   Luciferase

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 1, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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7. pSLIK-NFLAG-hEWSR1G511A-CMyc

   Plasmid

   #50734

   Purpose

   Produces lentivirus expressing human EWSR1G511A mutant with FLAG tag at its N-terminus and Myc tag at its C-terminus by co-transfection with psPAX2 and pMD2G

   Depositor

   Zissimos Mourelatos

   Article

   Couthouis et al Hum Mol Genet. 2012 Jul 1;21(13):2899-91

   Insert

   EWSR1 G511A (EWSR1 Human)
   

   Use

   Lentiviral

   Tags

   FLAG and Myc

   Expression

   Mutation

   Changed Gly 511 to Ala

   Promoter

   TRE

   Available since

   Jan. 16, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. pSLIK-NFLAG-hEWSR1P552L-CMyc

   Plasmid

   #50736

   Purpose

   Produces lentivirus expressing human EWSR1P552L mutant with FLAG tag at its N-terminus and Myc tag at its C-terminus by co-transfection with psPAX2 and pMD2G

   Depositor

   Zissimos Mourelatos

   Article

   Couthouis et al Hum Mol Genet. 2012 Jul 1;21(13):2899-91

   Insert

   EWSR1 P552L (EWSR1 Human)
   

   Use

   Lentiviral

   Tags

   FLAG and Myc

   Expression

   Mutation

   Changed Pro 552 to Leu

   Promoter

   TRE

   Available since

   Jan. 16, 2014

   Availability

   Academic Institutions and Nonprofits only

9. pCEP4-CCR5(R5gp120-Hi)

   Plasmid

   #98954

   Purpose

   Mammalian expression plasmid for myc-tagged human CCR5 mutant R5gp120-Hi

   Depositor

   Erik Procko

   Article

   Heredia et al J Immunol. 2018 Apr 20. pii: jimmunol.18

   Insert

   CCR5 (CCR5 Human)
   

   Use

   Tags

   Signal/leader sequence from Influenza A virus HA …

   Expression

   Mammalian

   Mutation

   R5gp120-Hi variant: P8L, I9E, I12M, S17E, P19D, Q…

   Promoter

   CMV

   Available since

   April 24, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. R777-E288 Hs.ROS1-nostop

    Plasmid

    #70572

    Purpose

    Gateway ORF clone of human ROS1 [NM_002944.2] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    ROS1 (ROS1 Human)
    

    Use

    Gateway entry clone

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. pJUNB-donor

    Plasmid

    #112313

    Purpose

    CRISPR donor plasmid to tag human transcription factor JUNB with GFP

    Depositor

    Kevin White

    Insert

    JUNB homology arms flanking EGFP-IRES-Neo cassette (JUNB Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    hg38:19:12792992:C>G, hg38:19:12793018:T>G,…

    Promoter

    Available since

    Nov. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pBABE_HRASV12_Hyg

    Plasmid

    #195143

    Purpose

    HRas G12V overexpression vector with hygroymycin resistance

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    hRAS (HRAS Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    G12V

    Promoter

    Available since

    Feb. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. R777-E102 Hs.HRAS-nostop

    Plasmid

    #70386

    Purpose

    Gateway ORF clone of human HRAS [NM_005343.2] without stop codon (for C-terminal fusions)

    Depositor

    Dominic Esposito

    Insert

    HRAS (HRAS Human)
    

    Use

    Gateway entry clone

    Tags

    Expression

    Mutation

    Promoter

    Available since

    March 1, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. 33-G-X5-pEF1/V5-His

    Plasmid

    #111605

    Purpose

    Express human 33-G-X5 in 293T cells

    Depositor

    Timothy Springer

    Article

    Qin et al Cell. 2018 Jun 28;174(1):156-171.e16. do

    Insert

    human LRRC33 and GARP chimeria (NRROS Human)
    

    Use

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    July 12, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCas9-HE

    Plasmid

    #109400

    Purpose

    Expresses Cas9 fusion to HE (HDR-enhancer) domain of human CtIP protein

    Depositor

    Jean-Paul Concordet

    Article

    Charpentier et al Nat Commun. 2018 Mar 19;9(1):1133. doi:

    Insert

    HDR-Enhancer domain of human CtIP protein (RBBP8 Human)
    

    Use

    Tags

    Expression

    Mutation

    Promoter

    Available since

    June 15, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pcDNA5-Flag-Med26

    Plasmid

    #49250

    Purpose

    Mammalian expression of flag-tagged Med26

    Depositor

    Joan Conaway, Ronald Conaway

    Article

    Takahashi et al Cell. 2011 Jul 8;146(1):92-104.

    Insert

    Med 26 (MED26 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Dec. 5, 2013

    Availability

    Academic Institutions and Nonprofits only

17. pENTR-myr-AKT-HA

    Plasmid

    #31790

    Depositor

    Xin Chen

    Article

    Calvisi et al Gastroenterology. 2011 Mar;140(3):1071-8

    Insert

    Akt1 (Akt1 Mouse)
    

    Use

    Entry vector

    Tags

    HA and Myr

    Expression

    Mutation

    Promoter

    Available since

    Oct. 21, 2011

    Availability

    Academic Institutions and Nonprofits only

18. PB-PE VQR

    Plasmid

    #162797

    Purpose

    All-in-one prime editor piggyBac transposon, VQR variant

    Depositor

    Tobias Cantz

    Article

    Eggenschwiler et al Sci Rep. 2021 Nov 12;11(1):22154. doi: 1

    Insert

    SpCas9_H840A_VQR-PE2-MMLV-RT(dBB)-P2A-PAC_dTK(dBB)
    

    Use

    CRISPR and Synthetic Biology; Piggybac transposon

    Tags

    SV40 NLS

    Expression

    Mammalian

    Mutation

    D1135V, R1335Q, T1337R

    Promoter

    CAG

    Available since

    Nov. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. PB-PE SpRY

    Plasmid

    #179082

    Purpose

    All-in-one prime editor piggyBac transposon, SpRY variant

    Depositor

    Tobias Cantz

    Article

    Eggenschwiler et al Sci Rep. 2021 Nov 12;11(1):22154. doi: 1

    Insert

    SpCas9 SpRY_H480A-PE2-MMLV-RT(dBB)-P2A-PAC_dTK(dBB)
    

    Use

    CRISPR and Synthetic Biology; Piggybac transposon

    Tags

    SV40 NLS

    Expression

    Mammalian

    Mutation

    A61R, L1111R, D1135L, S1136W, G1218K, E1219Q, N13…

    Promoter

    CAG

    Available since

    Jan. 25, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. PB-PE xCas9

    Plasmid

    #172652

    Purpose

    All-in-one prime editor piggyBac transposon (xCas9)

    Depositor

    Tobias Cantz

    Article

    Eggenschwiler et al Sci Rep. 2021 Nov 12;11(1):22154. doi: 1

    Insert

    xCas9_H840A-PE2-MMLV-RT(dBB)-P2A-PAC_dTK(dBB)
    

    Use

    CRISPR and Synthetic Biology; Piggybac transposon

    Tags

    SV40 NLS

    Expression

    Mammalian

    Mutation

    A262T, R324L, S409I, E480K, E543D, M694I, E1219V

    Promoter

    Available since

    Nov. 16, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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