Skip to main content
Addgene
Showing: 901 - 920 of 1018 results

  1. Nav1.5_1-2linker411-717_PPSYtoAASA1960-1996

    Plasmid
    #187732
    Purpose
    Express a chimera of the Nav1.5 linker between the first and second transmembrane domain with the motif surrounding PPSY; residues 1974-1977 PPSY mutated to AASA
    Depositor
    Sandra Gabelli
    Article
    Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi
    Insert
    Nav1.5 1,2linker residues 411-717 and Nav1.5 residues 1960-1996 PPSY mutated to AASA (SCN5A Human)
    Use
    Tags
    His-TEV
    Expression
    Bacterial
    Mutation
    deletion of residues 1-410 and 718-1959 and 1997-…
    Promoter
    Available since
    Oct. 24, 2024
    Availability
    Academic Institutions and Nonprofits only
    187732-plasmid-map-sequence-id-372456

    Enlarge

  3. KRD22_HBA1(HBA1reg-HBB-longHAs)

    Plasmid
    #232403
    Purpose
    AAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bp
    Depositor
    Kyle Cromer, Matthew Porteus
    Article
    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10
    Inserts
    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Human Hemoglobin Subunit Beta (HBB Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    April 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    232403-plasmid-map-sequence-id-466149

    Enlarge

  4. pCG_SARS-CoV2 NSP7/bat-CoV RaTG13 C-V5-tag

    Plasmid
    #179974
    Purpose
    Mammalian expression vector for SARS-CoV-2 Nsp7 or bat RaTG13 Nsp7, V5-tagged (SARS-CoV-2 Nsp7 and RaTG13 Nsp7 have the same amino acid sequence and codon optimized sequence).
    Depositor
    Konstantin Sparrer
    Article
    Hayn et al Cell Rep. 2021 May 18;35(7):109126.
    Insert
    SARS-CoV-2 Nsp7 (ORF1ab Synthetic)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    human codon-optimized
    Promoter
    Available since
    Feb. 7, 2022
    Availability
    Academic Institutions and Nonprofits only
    179974-plasmid-map-sequence-id-353863

    Enlarge

  5. pSG5-hPXR-K62Q

    Plasmid
    #67766
    Purpose
    Expression hPXR mutant K62Q in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Glutamine
    Promoter
    SV40
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only
    67766-plasmid-map-sequence-id-119289

    Enlarge

  6. pSG5-hPXR-K62R

    Plasmid
    #67765
    Purpose
    Expression hPXR mutant K62R in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Arginine
    Promoter
    SV40
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only
    67765-plasmid-map-sequence-id-119285

    Enlarge

  7. pCMX-hPXR-K62R

    Plasmid
    #67768
    Purpose
    Expression hPXR mutant K62R in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Arginine
    Promoter
    CMV
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only

  8. pCMX-hPXR-K62Q

    Plasmid
    #67767
    Purpose
    Expression hPXR mutant K62Q in Mammalian Cells
    Depositor
    Sridhar Mani
    Insert
    human pregnane X receptor (PXR) (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    lysine 62 to Glutamine
    Promoter
    CMV
    Available since
    July 22, 2015
    Availability
    Academic Institutions and Nonprofits only

  10. pCDNA3-hPXR-FL-T248E

    Plasmid
    #41617
    Depositor
    Sridhar Mani
    Insert
    hPXR-FL-T248E (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    N10D and T248E
    Promoter
    CMV
    Available since
    March 11, 2013
    Availability
    Academic Institutions and Nonprofits only

  11. 8061-E48

    Plasmid
    #234285
    Purpose
    Gateway ORF Entry clone of mouse Amhr2 with stop codon (for native or N-terminal fusions)
    Depositor
    Dominic Esposito
    Insert
    Amhr2 (Amhr2 Mouse)
    Use
    Gateway entry clone
    Tags
    Expression
    Mutation
    Promoter
    Available since
    May 5, 2025
    Availability
    Academic Institutions and Nonprofits only
    234285-plasmid-map-sequence-id-469782

    Enlarge

  12. pCDNA3-hPXR-FL-K277Q

    Plasmid
    #41618
    Depositor
    Sridhar Mani
    Insert
    hPXR-FL-K277Q (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    N10D and K277Q
    Promoter
    CMV
    Available since
    March 11, 2013
    Availability
    Academic Institutions and Nonprofits only

  19. ACVR1A

    Plasmid
    #74650
    Purpose
    Baculovirus expression for structure determination; may not be full ORF
    Depositor
    Nicola Burgess-Brown
    Insert
    ACVR1A (ACVR1 Human)
    Use
    Baculovirus
    Tags
    His-6-TEV
    Expression
    Mutation
    R206H
    Promoter
    PH
    Available since
    April 21, 2016
    Availability
    Academic Institutions and Nonprofits only

  20. pSH-hPXR-LBD-T248E

    Plasmid
    #41619
    Depositor
    Sridhar Mani
    Insert
    hPXR-LBD-T248E (NR1I2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    contains human PXR ligand binding domain (LBD, aa…
    Promoter
    pEN1 (chimeric HIV-1 LTR enhancer and HTLV-I LTR …
    Available since
    April 24, 2013
    Availability
    Academic Institutions and Nonprofits only
Showing: 901 - 920 of 1018 results