We narrowed to 9,906 results for: UTY

1. pLKO_Ollas.AU1.C_NGFR

   Plasmid

   #158314

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Ollas.AU1.C

   Expression

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available Since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLKO_HA.AU1.V5_NGFR

   Plasmid

   #158235

   Purpose

   Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

   Depositor

   Brian Brown

   Article

   Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

   Insert

   Pro-Code Tagged human dNGFR (NGFR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   HA.AU1.V5

   Expression

   Mutation

   Truncation of the signaling domain

   Promoter

   EF1a

   Available Since

   Sept. 3, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDGB3 omega1 Tnos:nptII:Pnos - P35S:Cas9:Tnos - P35S:DsRed:Tnos (GB2235)

   Plasmid

   #160646

   Purpose

   Module for the constitutive expression of the nptII, Cas9 and DsRed genes.

   Depositor

   Diego Orzaez

   Article

   Vazquez-Vilar et al Front Plant Sci. 2021 Jul 1;12:689937. d

   Insert

   tNos:nptII:PNos-P35s:Cas9:tNos-P35s:DsRed:tNos
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   BsaI and BsmBI sites removed

   Promoter

   Pnos, 35S, 35S

   Available Since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. YFP(1-158)-gamma-2 in pcDNAI/Amp

   Plasmid

   #55762

   Purpose

   An amino-terminal YFP fragment was fused to Ggamma2. When co-expressed with a carboxyl terminal YFP or CFP fragment fused to a Gbeta subunit with which it interacts, a fluorescent signal is produced.

   Depositor

   Catherine Berlot

   Article

   Yost et al Mol Pharmacol. 2007 Oct;72(4):812-25. Ep

   Insert

   YFP(1-158)-gamma-2 (GNG2 Human, Aequorea victoria)
   

   Use

   Tags

   YFP(1-158) was fused to the amino terminus of Gga…

   Expression

   Mammalian

   Mutation

   YFP (1-158) includes a substitution of Met for Gl…

   Promoter

   CMV

   Available Since

   July 30, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. MSCV-PIG-METTL14-R298P

   Plasmid

   #141119

   Purpose

   Retroviral overexpression of mutant METTL14 in mammalian cells.

   Depositor

   Jianjun Chen

   Article

   Weng et al Cell Stem Cell. 2018 Feb 1;22(2):191-205

   Insert

   METTL14 (METTL14 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   Substitution - Missense, position 298, R➞P

   Promoter

   Available Since

   June 26, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. pPHAGE-C20orf24- C20orf24-3’UTR-WT

   Plasmid

   #128508

   Purpose

   Lentiviral constitutive expression of C20orf24 under control of its native WT 3'UTR of human C20orf24.

   Depositor

   Mohan Babu

   Article

   Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

   Insert

   RAB5IF (RAB5IF Human)
   

   Use

   Lentiviral

   Tags

   FLAG and HA tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Sept. 16, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pXPR_BRD003-sgWRN3

   Plasmid

   #125773

   Purpose

   constitutive expression of a guide RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   sgWRN3 (WRN Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   June 11, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. L4342 TNFR1 CTEVp chain in PolyTX-mTagBFP2

   Plasmid

   #244178

   Purpose

   Constitutive expression of a MESA CTEVp chain encoding (N to C): TNFR1SS-3xFLAG-TNFR1ECD(dMMP)-TNFR1TMD-CTEVp(75S)-PRS(M)-VP64-ZF6

   Depositor

   Joshua Leonard

   Article

   Edelstein et al Nat Chem Biol. 2025 Aug 22:10.1038/s4158

   Insert

   MESA CTEVp chain with human TNFR1 SS, ECD (no MMP site) and TMD, CTEVp (190K), TEVp PRS (M in P1'), and synTF (VP64-ZF6) (TNFRSF1A Synthetic, Human)
   

   Use

   Synthetic Biology

   Tags

   TNFR1 signal peptide - 3xFLAG

   Expression

   Mammalian

   Mutation

   CTEVp_190K

   Promoter

   hEF1a

   Available Since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. L4341 TNFR1 NTEVp chain (deleted MMP site) in PolyTX-mNeonGreen

   Plasmid

   #244176

   Purpose

   Constitutive expression of a MESA NTEVp chain encoding (N to C): TNFR1SS-3xFLAG-TNFR1ECD(dMMP)-TNFR1TMD-NTEVp(75S)

   Depositor

   Joshua Leonard

   Article

   Edelstein et al Nat Chem Biol. 2025 Aug 22:10.1038/s4158

   Insert

   MESA NTEVp chain with human TNFR1 SS and ECD (no MMP site), murine CD28 TMD, and NTEVp 75S mutant (TNFRSF1A Synthetic, Human)
   

   Use

   Synthetic Biology

   Tags

   TNFR1 signal peptide - 3xFLAG

   Expression

   Mammalian

   Mutation

   NTEVp_75S

   Promoter

   hEF1a

   Available Since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. MB 94C thsS(t3)R-Bxb1_P7-sfGFP_mCherry

    Plasmid

    #232471

    Purpose

    Optimized thiosulfate sensor with recombinase switch and fluorescent reporter (GFP), constitutive mCherry

    Depositor

    Mikhail Shapiro

    Article

    Buss et al Nat Commun. 2025 Aug 25;16(1):7931. doi:

    Inserts

    thsS(t3)
    thsR
    PphsA342
    sfGFP
    AxeTxe
    mCherry
    Bxb1 integrase
    

    Use

    Tags

    ssrA degradation tag

    Expression

    Bacterial

    Mutation

    Contains the following mutations K286Q, Q350H, I…

    Promoter

    J23100 (TTGACGGCTAGCTCAGTCCTAGGTACAGTGCTAGC), J23…

    Available Since

    Sept. 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. MB 39Vm13 ttrSR(m13)-bARGSer

    Plasmid

    #232472

    Purpose

    Optimized tetrathionate sensor with acoustic reporter genes (bARGSer)

    Depositor

    Mikhail Shapiro

    Article

    Buss et al Nat Commun. 2025 Aug 25;16(1):7931. doi:

    Inserts

    ttrS
    ttrR
    PttrB185-269
    bARGSer
    AxeTxe
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    the gene Ser39006_001280 was deleted from the clu…

    Promoter

    Constitutive (TTGATAGCTAGCTCAGTCCTAGGTATTGTGCTAGC…

    Available Since

    Sept. 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLentiX1-[TRE3G-EGFP(miRE.FF4)-FMRP-TS.FF6x1-bGH]-EFS-rtTA-P2A-mRuby2-WPRE

    Plasmid

    #235307

    Purpose

    Lentiviral expression of ComMAND open-loop circuit regulating EGFP-FMRP (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    EGFP-Fmr1 (Fmr1 Mouse)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLentiX1-[TRE3G-FXN-P2A-mRuby2-bGH]-EFS-rtTA-P2A-mGL-WPRE

    Plasmid

    #235303

    Purpose

    Lentiviral expression of ComMAND base gene regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLentiX1-[TRE3G-FXN-P2A-mRuby2(miRE.FF4)-TS.FF6x1-bGH]-EFS-rtTA-P2A-mGL-WPRE

    Plasmid

    #235304

    Purpose

    Lentiviral expression of ComMAND open-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pLentiX1-[TRE3G-EGFP(miRE.FF4)-FMRP-TS.FF4x1-bGH]-EFS-rtTA-P2A-mRuby2-WPRE

    Plasmid

    #235308

    Purpose

    Lentiviral expression of ComMAND closed-loop circuit regulating EGFP-FMRP (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    EGFP-Fmr1 (Fmr1 Mouse)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLentiX1-[TRE3G-FXN-P2A-mRuby2(miRE.FF4)-TS.FF4x1-bGH]-EFS-rtTA-P2A-mGL-WPRE

    Plasmid

    #235305

    Purpose

    Lentiviral expression of ComMAND closed-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    FXN-P2A-mRuby2 (FXN Human)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLentiX1-[TRE3G-EGFP-FMRP-bGH]-EFS-rtTA-P2A-mRuby2-WPRE

    Plasmid

    #235306

    Purpose

    Lentiviral expression of ComMAND base gene regulating EGFP-FMRP (therapeutically relevant gene)

    Depositor

    Kate Galloway

    Article

    Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

    Insert

    EGFP-Fmr1 (Fmr1 Mouse)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    TRE3G (3rd-generation Tet system)

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pcDNA3.1-DDR1-F866Y-V5/HIS

    Plasmid

    #236009

    Purpose

    expression of the F866Y kinase defective mutant variant of human DDR1 that might be associated with lung Adenocarcinoma

    Depositor

    Pavel Krejčí

    Article

    Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

    Insert

    human DDR1-F866Y receptor tyrosine kinase, full length (DDR1 Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    F866Y substitution

    Promoter

    CMV

    Available Since

    April 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLL5.0_shRNAHsCavin1_MmCavin1_EGFP

    Plasmid

    #229689

    Purpose

    Lentiviral expression of shRNA targeting Cavin1 + reconstitution of mouse Cavin1 (Cavin1 rescue)

    Depositor

    Alpha Yap

    Article

    Brooks et al Mol Biol Cell. 2023 Nov 1;34(12):ar120.

    Inserts

    shRNA for hCavin1 (CAVIN1 Human)
    mCavin1 (Cavin1 Mouse)
    

    Use

    Lentiviral

    Tags

    EGFP

    Expression

    Mutation

    Promoter

    LTR viral promoter

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-CMV-GFP-LA

    Plasmid

    #206197

    Purpose

    Expresses GFP-tagged human Lamin-A protein by the constitutive CMV promoter in mice

    Depositor

    Yuxuan Guo

    Article

    Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

    Insert

    Lmna (LMNA )
    

    Use

    AAV

    Tags

    GFP

    Expression

    Mutation

    Promoter

    CMV

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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