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pSicoR-ADAM29i2

Plasmid

#59607

Purpose

Expression of shRNA against human ADAM29

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

ADAM29 (ADAM29 Human)

Use

RNAi

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

Oct. 15, 2014

Availability

Academic Institutions and Nonprofits only
pSicoR-ADAM7i2

Plasmid

#59603

Purpose

Expression of shRNA against human ADAM7

Depositor

Miguel Ramalho-Santos

Article

Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

Insert

ADAM7 (ADAM7 Human)

Use

RNAi

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

Sept. 26, 2014

Availability

Academic Institutions and Nonprofits only
pBS ADAMTS3

Plasmid

#19205

Depositor

Cliff Tabin

Article

Bandyopadhyay et al Dev Biol. 2008 Sep 1;321(1):162-74. doi:

Insert

ADAM metallopeptidase with thrombospondin type 1 (ADAMTS3 Chicken)

Use

Tags

Expression

Bacterial

Mutation

Promoter

Available since

Sept. 15, 2008

Availability

Academic Institutions and Nonprofits only
pmGFP-ADAR1-p110

Plasmid

#117928

Purpose

ADAR1-p110 expression plasmid.

Depositor

Kumiko Ui-Tei

Article

Galipon et al Genes (Basel). 2017 Feb 11;8(2). pii: ge

Insert

ADAR1-p110 (ADAR Human)

Use

Tags

myc-GFP

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Dec. 4, 2018

Availability

Academic Institutions and Nonprofits only

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pmGFP-ADAR1-p150

Plasmid

#117927

Purpose

ADAR1-p150 expression plasmid.

Depositor

Kumiko Ui-Tei

Article

Galipon et al Genes (Basel). 2017 Feb 11;8(2). pii: ge

Insert

ADAR1-p150 (ADAR Human)

Use

Tags

myc-GFP

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Dec. 4, 2018

Availability

Academic Institutions and Nonprofits only

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pDV10_pCMV-ADAR1-p150

Plasmid

#200405

Purpose

Expresses ADAR1 (p150 isoform) constitutively in mammalian cells

Depositor

James Collins

Article

Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

Insert

ADAR-p150

Use

Synthetic Biology

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 30, 2023

Availability

Academic Institutions and Nonprofits only

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pDV09_pCMV-ADAR1-p110

Plasmid

#200404

Purpose

Expresses ADAR1 (p110 isoform) constitutively in mammalian cells

Depositor

James Collins

Article

Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

Insert

ADAR-p110

Use

Synthetic Biology

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 30, 2023

Availability

Academic Institutions and Nonprofits only

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ABE8e(TadA-8e V106W)

Plasmid

#138495

Purpose

A-to-G base editor

Depositor

David Liu

Article

Richter et al Nat Biotechnol. 2020 Jul;38(7):883-891.

Insert

ecTadA(8e V106W)-nSpCas9

Use

Tags

Expression

Mammalian

Mutation

TadA-8e V106W

Promoter

Available since

March 17, 2020

Availability

Academic Institutions and Nonprofits only

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CamKII-ADAM23-pHluorin

Plasmid

#185539

Purpose

Expresses ADAM23-pHluorin under the CamKII promoter

Depositor

Jaime de Juan-Sanz

Article

Cuhadar et al Cell Rep. 2024 May 28;43(5):114186. doi:

Insert

ADAM23 (Adam23 Rat)

Use

Lentiviral

Tags

pHluorin

Expression

Mammalian

Mutation

Promoter

CamKII

Available since

May 3, 2024

Availability

Academic Institutions and Nonprofits only

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pCMV-TadA8e-PcrA

Plasmid

#221228

Purpose

Express HACE Editor as a fusion of TadA-8e adenosine deaminase and PcrA helicase.

Depositor

Fei Chen

Article

Chen et al Science. 2024 Oct 11;386(6718):eadn5876.

Insert

TadA8e-PcrA

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

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pHAGE Flag HA ADAR2 CI

Plasmid

#237997

Purpose

Inducible lentiviral expression of ADAR2 CI

Depositor

David Pellman

Article

Tang et al Nature. 2022 Jun;606(7916):930-936. doi:

Insert

ADAR2 (ADARB1 Human)

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

E396A

Promoter

Available since

April 24, 2025

Availability

Academic Institutions and Nonprofits only

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pDV24_AAV2_DART-VADAR_iRFP720-sensor

Plasmid

#200411

Purpose

AAV vector encoding a DART-VADAR sensor for iRFP720 mRNA

Depositor

James Collins

Article

Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

Insert

DART VADAR sensor

Use

AAV and Synthetic Biology

Tags

MCP-ADAR2dd(E488Q)-NES, TagBFP, and mNeonGreen

Expression

Mammalian

Mutation

Promoter

CMV

Available since

June 30, 2023

Availability

Academic Institutions and Nonprofits only

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pCS4333 yeTadA1.0-T7 RNAP

Plasmid

#137735

Purpose

pCS4333 CEN/ARS vector, PGAL1-yeTadA1.0-100AA linker-T7 RNAP-TCYC1, TRP1 selectable marker

Depositor

Christina Smolke

Article

Cravens et al Nat Commun. 2021 Mar 11;12(1):1579. doi:

Insert

yeTadA1.0-T7 RNAP

Use

Tags

Expression

Bacterial and Yeast

Mutation

E366G (See depositor comment below)

Promoter

Available since

Jan. 29, 2020

Availability

Academic Institutions and Nonprofits only

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pDV06.2c_DART-VADAR_iRFP720-sensor

Plasmid

#200410

Purpose

pDV06 with iRFP720-targeted sensor sequence inserted. Expresses TagBFP constitutively. Expresses mNeonGreen and MCP-ADAR upon detection of the mRNA produced by pDV05.0, pDV05.1 and pDV05.2

Depositor

James Collins

Article

Gayet et al Nat Commun. 2023 Mar 11;14(1):1339. doi:

Insert

Closed-loop DART VADAR sensor detecting iRFP720

Use

Synthetic Biology

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 30, 2023

Availability

Academic Institutions and Nonprofits only

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pCMV3Tag8li-hADARB2-3xFLAG

Plasmid

#165470

Purpose

Human ADARB2 mammalian expression vector with 3 C-terminal FLAG tags.

Depositor

Martin Dorf

Article

Li et al Proc Natl Acad Sci U S A. 2014 May 13;11

Insert

Adenosine deaminase RNA specific B2 (inactive) (ADARB2 Human)

Use

Tags

3xFLAG

Expression

Mammalian

Mutation

Promoter

CMV

Available since

March 17, 2021

Availability

Academic Institutions and Nonprofits only

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pCMV-TadA8e-BLM

Plasmid

#221226

Purpose

Express HACE Editor as a fusion of TadA-8e adenosine deaminase and BLM helicase.

Depositor

Fei Chen

Article

Chen et al Science. 2024 Oct 11;386(6718):eadn5876.

Insert

TadA8e-BLM

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Sept. 6, 2024

Availability

Academic Institutions and Nonprofits only

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pDY1243-Fluorescent RADARS

Plasmid

#182540

Purpose

Express Fluorescent RADARS in bicistronic vector with mCherry as control gene

Depositor

Jonathan Gootenberg, Omar Abudayyeh

Article

Jiang et al Nat Biotechnol. 2022 Oct 27. pii: 10.103

Insert

mNeon

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

April 6, 2022

Availability

Academic Institutions and Nonprofits only

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FoxO1-ADA-GFP

Plasmid

#35640

Depositor

Domenico Accili

Article

Qiang et al J Biol Chem. 2010 Aug 27;285(35):27396-4

Insert

FoxO1-ADA-GFP (Foxo1 Mouse)

Use

Tags

Flag, GFP, and Myc

Expression

Mammalian

Mutation

T24A, S253D and S316A mutations

Promoter

CMV

Available since

May 2, 2012

Availability

Academic Institutions and Nonprofits only

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FLAG-Foxo1ADA(pCMV5)

Plasmid

#12149

Depositor

Domenico Accili

Article

Kitamura et al Cell Metab. 2005 Sep . 2(3):153-63.

Insert

Foxo1 ADA (Foxo1 Mouse)

Use

Tags

Flag and Myc

Expression

Mammalian

Mutation

Threonine 24 to Alanine (A) and Serine 253 to Asp…

Promoter

CMV

Available since

June 13, 2007

Availability

Academic Institutions and Nonprofits only
pCMV-TadA8e-Ns3h

Plasmid

#221227

Purpose

Express HACE Editor as a fusion of TadA-8e adenosine deaminase and Ns3h helicase.

Depositor

Fei Chen

Article

Chen et al Science. 2024 Oct 11;386(6718):eadn5876.

Insert

TadA8e-Ns3h

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 24, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge