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pFastBac-CHD7 (787-2138)

Plasmid

#170146

Purpose

Expresses residues 787-2138 of CHD7 in insect cells

Depositor

Robert Kingston

Article

Bouazoune et al Proc Natl Acad Sci U S A. 2012 Nov 20;10

Insert

chromodomain helicase DNA binding protein 7 (CHD7 Human)

Tags

FLAG

Expression

Insect

Mutation

N-terminal truncation of residues 1-786; C-termin…

Available Since

July 14, 2021

Availability

Academic Institutions and Nonprofits only

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pFastBac-CHD7 (936-2997)

Plasmid

#170147

Purpose

Expresses residues 936-2997 of CHD7 in insect cells

Depositor

Robert Kingston

Article

Bouazoune et al Proc Natl Acad Sci U S A. 2012 Nov 20;10

Insert

chromodomain helicase DNA binding protein 7 (CHD7 Human)

Tags

FLAG

Expression

Insect

Mutation

N-terminal truncation of residues 1-935

Available Since

July 14, 2021

Availability

Academic Institutions and Nonprofits only

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pCMV HA hRB delta CDK + T826

Plasmid

#58921

Purpose

mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and T826 restored

Depositor

Steven Dowdy

Article

Narasimha et al Elife. 2014 May 29:e02872. doi: 10.7554/

Insert

Rb (RB1 Human)

Tags

HA

Expression

Mammalian

Mutation

delta CDK* with T826 restored

Promoter

CMV

Available Since

Oct. 2, 2014

Availability

Academic Institutions and Nonprofits only
Frt-hspB4

Plasmid

#63095

Purpose

Expression of HSPB4 (small HSP) in mammalian cells

Depositor

Harm Kampinga

Article

Vos et al Hum Mol Genet. 2010 Dec 1;19(23):4677-93

Insert

hspb4 (CRYAA Human)

Expression

Mammalian

Promoter

CMV

Available Since

March 18, 2015

Availability

Academic Institutions and Nonprofits only

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pCMV HA hRB delta CDK + S249

Plasmid

#58908

Purpose

mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S249 restored

Depositor

Steven Dowdy

Article

Narasimha et al Elife. 2014 May 29:e02872. doi: 10.7554/

Insert

Rb (RB1 Human)

Tags

HA

Expression

Mammalian

Mutation

delta CDK* with S249 restored

Promoter

CMV

Available Since

Oct. 2, 2014

Availability

Academic Institutions and Nonprofits only
MAC_N_CDK7

Plasmid

#111684

Purpose

MAC-tagged gene expression

Depositor

Markku Varjosalo

Article

Liu et al Nat Commun. 2018 Mar 22;9(1):1188. doi:

Insert

CDK7 (CDK7 Human)

Expression

Mammalian

Available Since

June 14, 2018

Availability

Academic Institutions and Nonprofits only

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pRC/CMV-TYK2V362F-VSV

Plasmid

#139345

Purpose

Expression of TYK2 V362F protein (rs2304256)

Depositor

Sandra Pellegrini

Article

Gauzzi et al J Biol Chem. 1996 Aug 23;271(34):20494-5

Insert

TYK2 cDNA with 267nt of 5' UTR (TYK2 Human)

Tags

VSV

Expression

Mammalian

Mutation

V362F

Promoter

CMV

Available Since

March 24, 2020

Availability

Academic Institutions and Nonprofits only

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pAAV-U6-Diras2_1-hSyn::mCherry.3xFLAG-WPRE

Plasmid

#120393

Purpose

pAAV plasmid expressing Diras2 shRNA1 under the U6 promoter and mCherry.3XFLAG under the hSyn promoter

Depositor

Florian Freudenberg

Article

Grunewald et al J Atten Disord. 2019 Jan 9:1087054718822

Insert

Diras2 shRNA (Diras2 Mouse)

Use

AAV and RNAi

Tags

mCherry.3XFLAG

Promoter

U6

Available Since

Feb. 14, 2019

Availability

Academic Institutions and Nonprofits only

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pMCSF-R(m40)-luc

Plasmid

#12425

Depositor

Dong-Er Zhang

Article

Zhang et al Mol Cell Biol. 1994 Jan . 14(1):373-81.

Insert

M-CSF receptor promoter fragment (CSF1R Human)

Use

Luciferase

Mutation

PU.1 binding site mutation (created a KpnI site i…

Available Since

Dec. 15, 2006

Availability

Academic Institutions and Nonprofits only
GST-BRDCH2 (1079-1317)

Plasmid

#99339

Purpose

Bacterial expression of mouse CBP BRDCH2 domains as a GST fusion

Depositor

Peter Wright

Article

Park et al FEBS Lett. 2013 Aug 19;587(16):2506-11.

Insert

mouse CBP BRDCH2 (1079-1317) (Crebbp Mouse)

Tags

GST

Expression

Bacterial

Available Since

Sept. 13, 2017

Availability

Academic Institutions and Nonprofits only

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pGEMT-GDNF

Plasmid

#119897

Purpose

Mouse GDNF In situ hybridization probe

Depositor

Wenqin Luo

Article

Fleming et al Elife. 2015 Apr 2;4:e06828. doi: 10.7554

Insert

glial cell line derived neurotrophic factor (Gdnf Mouse)

Use

In situ hybridization probe

Available Since

July 17, 2019

Availability

Academic Institutions and Nonprofits only

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pcDNA3.1(+)/Puro/FA/GFP-N--Grb2-4

Plasmid

#112839

Purpose

transient/stable overexpression

Depositor

Tomasz Prószyński

Article

Gingras et al J Cell Sci. 2016 Mar 1;129(5):898-911. d

Insert

Grb2 (Grb2 Mouse)

Tags

GFP

Expression

Mammalian

Mutation

SH3 (N-term) domain of Grb2

Available Since

Aug. 8, 2018

Availability

Academic Institutions and Nonprofits only

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CD8a-f-CTS-EGFP

Plasmid

#86063

Purpose

A mammalian expression plasmid encoding fibrocystin mimentic clone CD8a-f-CTS (CD8a luminal and transmembrane domains, fibrocystin ciliary targeting signal domains) with C-terminus EGFP.

Depositor

Lei Lu

Article

Madugula et al J Cell Sci. 2016 Oct 15;129(20):3922-393

Insert

Fibrocystin (Pkhd1 Mouse)

Tags

GFP

Expression

Mammalian

Mutation

contains CD8a luminal and transmembrane domains a…

Promoter

CMV

Available Since

May 8, 2017

Availability

Academic Institutions and Nonprofits only

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CFP-Rpp29-C1

Plasmid

#134546

Purpose

Expresses CFP-Rpp29 fusion protein

Depositor

Susan Janicki

Article

Newhart et al Mol Biol Cell. 2016 Apr 1;27(7):1154-69.

Insert

Rpp29 (POP4 Human)

Tags

CFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 10, 2020

Availability

Academic Institutions and Nonprofits only

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pCGN-HCF-1-N1011Δ382-450

Plasmid

#92322

Purpose

N-term of HCF-1 protein without amino acids 382-450

Depositor

Winship Herr

Article

Wilson et al Mol Cell Biol. 1997 Oct;17(10):6139-46.

Insert

HCF-1 (HCFC1 Human)

Tags

HA

Expression

Mammalian

Mutation

AA 2-1011 with internal deletion Δ382-450

Promoter

CMV

Available Since

Sept. 12, 2017

Availability

Academic Institutions and Nonprofits only

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pCGN-HCF-1-N450

Plasmid

#92321

Purpose

N-term 1-450 of HCF-1 protein

Depositor

Winship Herr

Article

Wilson et al Mol Cell Biol. 1997 Oct;17(10):6139-46.

Insert

HCF-1 (HCFC1 Human)

Tags

HA

Expression

Mammalian

Mutation

AA 2-450. Note that a SRRASGTYGRV amino-terminal …

Promoter

CMV

Available Since

Sept. 12, 2017

Availability

Academic Institutions and Nonprofits only

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pST_MAHS_RAMVA_81-236-FLAG (pBS0297)

Plasmid

#185328

Purpose

For the mammalian expression of the tardigrade protein MAHS_RAMVA_81-236-FLAG. This is one of the top performing targets in our apoptosis assay (it protected from apoptosis).

Depositor

Pamela Silver

Article

Veling et al ACS Synth Biol. 2022 Mar 18;11(3):1292-1

Insert

MAHS_RAMVA_81-236-FLAG

Tags

FLAG

Expression

Mammalian

Available Since

June 9, 2022

Availability

Academic Institutions and Nonprofits only

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FSW-HRP-V5-MDGA1

Plasmid

#82541

Purpose

Lentiviral vector for expressing HRP-MDGA1 in neurons

Depositor

Alice Ting

Article

Loh et al Cell. 2016 Aug 25;166(5):1295-1307.e21.

Insert

MDGA1 (MDGA1 Human)

Use

Lentiviral

Tags

HRP and V5

Expression

Mammalian

Promoter

Human Synapsin

Available Since

Sept. 21, 2016

Availability

Academic Institutions and Nonprofits only

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MO70-hJunctate - EF-mutant

Plasmid

#79597

Purpose

Transient and retroviral expression

Depositor

Yousang Gwack

Article

Srikanth et al Proc Natl Acad Sci U S A. 2012 May 29;10

Insert

junctate (ASPH Human)

Use

Retroviral

Tags

FLAG

Expression

Mammalian

Mutation

77DAD79 to 77AAA79

Promoter

CMV

Available Since

Aug. 17, 2016

Availability

Academic Institutions and Nonprofits only
pCMV HA hRb delta CDK + S230

Plasmid

#58907

Purpose

mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and S230 restored

Depositor

Steven Dowdy

Article

Narasimha et al Elife. 2014 May 29:e02872. doi: 10.7554/

Insert

Rb (RB1 Human)

Tags

HA

Expression

Mammalian

Mutation

delta CDK* with S230 restored

Promoter

CMV

Available Since

Oct. 2, 2014

Availability

Academic Institutions and Nonprofits only
pCMV HA hRB delta CDK + T252

Plasmid

#58910

Purpose

mammalian expression of human Rb with all Ser/Thr Cdk acceptor sites removed and T252 restored

Depositor

Steven Dowdy

Article

Narasimha et al Elife. 2014 May 29:e02872. doi: 10.7554/

Insert

Rb (RB1 Human)

Tags

HA

Expression

Mammalian

Mutation

delta CDK* with T252 restored

Promoter

CMV

Available Since

Oct. 2, 2014

Availability

Academic Institutions and Nonprofits only
EGFP-CCHD (p130Cas)

Plasmid

#145132

Purpose

Expresses CCH domain from p130Cas with an EGFP tag

Depositor

Johanna Ivaska

Article

Jacquemet et al Curr Biol. 2019 Jan 21;29(2):202-216.e7.

Insert

p130Cas CCH domain (BCAR1 Human)

Tags

EGFP

Expression

Mammalian

Promoter

CMV

Available Since

July 28, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
mPapaya1-Actin-C-18

Plasmid

#56400

Purpose

Localization: Actin, Excitation: 530, Emission: 541

Depositor

Michael Davidson

Article

Hoi et al Chem Biol. 2013 Oct 24;20(10):1296-304.

Insert

Actin (ACTB Human)

Tags

mPapaya1

Expression

Mammalian

Promoter

CMV

Available Since

Dec. 18, 2014

Availability

Academic Institutions and Nonprofits only
pHH0103_CRKL-2/2

Plasmid

#91364

Purpose

Protein expression and purification of human SH3 domain construct CRKL-2/2

Depositor

Sachdev Sidhu

Article

Teyra et al Structure. 2017 Oct 3;25(10):1598-1610.e

Insert

CRKL-2/2 (CRKL Human)

Expression

Bacterial

Available Since

March 19, 2018

Availability

Academic Institutions and Nonprofits only

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FSW-HRP-V5-MDGA2

Plasmid

#82542

Purpose

Lentiviral vector for expressing HRP-MDGA2 in neurons

Depositor

Alice Ting

Article

Loh et al Cell. 2016 Aug 25;166(5):1295-1307.e21.

Insert

MDGA2 (Mdga2 Rat)

Use

Lentiviral

Tags

HRP and V5

Expression

Mammalian

Promoter

Human Synapsin

Available Since

April 12, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
gh261

Plasmid

#106852

Purpose

expression of gRNA targeting ALG8

Depositor

Eric-Paul Bennett

Article

Narimatsu et al Glycobiology. 2018 Jan 5. pii: 4791732.

Insert

ALG8 (ALG8 Human)

Expression

Mammalian

Available Since

Nov. 9, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
mPapaya-Actin-C-18

Plasmid

#56395

Purpose

Localization: Actin, Excitation: 530, Emission: 541

Depositor

Michael Davidson

Article

Hoi et al Chem Biol. 2013 Oct 24;20(10):1296-304.

Insert

Actin (ACTB Human)

Tags

mPapaya

Expression

Mammalian

Promoter

CMV

Available Since

Dec. 18, 2014

Availability

Academic Institutions and Nonprofits only

Enlarge
pRCIscript-crhr1_TAL1B

Plasmid

#44235

Depositor

Karl Clark, Stephen Ekker

Article

Bedell et al Nature. 2012 Nov 1;491(7422):114-8. doi:

Insert

crhr1 pTAL scaffold 1B (crhr1 Zebrafish)

Use

Mrna transcription vector

Promoter

T3

Available Since

April 10, 2013

Availability

Academic Institutions and Nonprofits only

Enlarge
pRCIscript-crhr1_TAL1A

Plasmid

#44234

Depositor

Karl Clark, Stephen Ekker

Article

Bedell et al Nature. 2012 Nov 1;491(7422):114-8. doi:

Insert

crhr1 pTAL scaffold 1A (crhr1 Zebrafish)

Use

Mrna transcription vector

Promoter

T3

Available Since

April 10, 2013

Availability

Academic Institutions and Nonprofits only

Enlarge
Avi-TAZ1

Plasmid

#254289

Purpose

Bacterial expression of His- and Avi-tagged CBP TAZ1

Depositor

Rebecca Berlow

Article

Do et al bioRxiv [Preprint]. 2026 Jan 21:2026.01.

Insert

CBP TAZ1 (340-439) (Crebbp Mouse)

Tags

8X His-tag + Avi-tag

Expression

Bacterial

Promoter

T7

Available Since

April 2, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pT7II-dGAEtau

Plasmid

#249558

Purpose

Recombinant protein synthesis of dGAE (AD Core) human Tau cysless variant.

Depositor

Jeff Kuret

Article

Pettis et al Anal Biochem. 2026 Mar 4;714:116095. doi

Insert

Tau (dGAE) (MAPT Human)

Expression

Bacterial

Available Since

Jan. 22, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pT7II-dGAE C322A

Plasmid

#249559

Purpose

Recombinant protein synthesis of dGAE (AD Core) human Tau (C322A mutant) cysless variant.

Depositor

Jeff Kuret

Article

Pettis et al Anal Biochem. 2026 Mar 4;714:116095. doi

Insert

Tau (dGAE C322A) (MAPT Human)

Expression

Bacterial

Available Since

Jan. 14, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
pT7II-2N4Rtau I277P/I308P

Plasmid

#249557

Purpose

Recombinant protein synthesis of I277P/I308P mutant of human 2N4R Tau

Depositor

Jeff Kuret

Article

Pettis et al Anal Biochem. 2026 Mar 4;714:116095. doi

Insert

Tau (2N4R - I277P/I308P) (MAPT Human)

Expression

Bacterial

Available Since

Jan. 14, 2026

Availability

Academic Institutions and Nonprofits only

Enlarge
Lyn-FRB_star-P2A-mVenus-FKBP-5ptase

Plasmid

#241305

Purpose

Mammalian expression of Lyn-FRB_star and mVenus-FKBP-5ptase of INPP5E

Depositor

Justin Taraska

Article

Obashi et al Structure. Volume 34, Issue 1, 8 January

Insert

INPP5E (INPP5E Human)

Tags

mVenus, FKBP

Expression

Mammalian

Mutation

214-644 aa

Promoter

CMV

Available Since

Dec. 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
Syntaxin1A(I233A,R210H,K84TAG)-mCherry

Plasmid

#241300

Purpose

Mammalian expression of syntaxin-1(I233A,K84TAG,R210H) fused to mCherry for genetic code expansion via Amber codon supression

Depositor

Justin Taraska

Article

Obashi et al Structure. Volume 34, Issue 1, 8 January

Insert

Syntaxin-1A (Stx1a Rat)

Tags

mCherry

Expression

Mammalian

Mutation

I233A,K84TAG,R210H

Promoter

CMV

Available Since

Dec. 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
Syntaxin1A(K264A,K265A,K84TAG)-mCherry

Plasmid

#241301

Purpose

Mammalian expression of syntaxin-1(K264A,K265A,K84TAG) fused to mCherry for genetic code expansion via Amber codon supression

Depositor

Justin Taraska

Article

Obashi et al Structure. Volume 34, Issue 1, 8 January

Insert

Syntaxin-1A (Stx1a Rat)

Tags

mCherry

Expression

Mammalian

Mutation

K264A,K265A,K84TAG

Promoter

CMV

Available Since

Dec. 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
mVenus-synaptojanin1(498-901)-CAAX

Plasmid

#241303

Purpose

Mammalian expression of truncated form of synaptojanin-1 with CAAX motif fused to mVenus

Depositor

Justin Taraska

Article

Obashi et al Structure. Volume 34, Issue 1, 8 January

Insert

Synaptojanin-1 (SYNJ1 Human)

Tags

mVenus

Expression

Mammalian

Mutation

498-901 aa

Promoter

CMV

Available Since

Dec. 11, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-H4-BioID2-HA

Plasmid

#232026

Purpose

mammalian expression (CMV promoter) of histone H4 fused to BioID2-HA

Depositor

Primo Schaer

Article

Richina et al Cell Mol Life Sci. 2025 Nov 25. doi: 10.

Insert

H4 (H4C14 Human)

Tags

BioID2-HA

Expression

Mammalian

Available Since

Nov. 26, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV-mTDGa-BioID2-HA

Plasmid

#232027

Purpose

mammalian expression (CMV promoter) of murine TDG fused to BioID2-HA

Depositor

Primo Schaer

Article

Richina et al Cell Mol Life Sci. 2025 Nov 25. doi: 10.

Insert

Tdg (Tdg Mouse)

Tags

BioID2-HA

Expression

Mammalian

Promoter

CMV

Available Since

Nov. 26, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pGEM-7zf(+)_mmSRA1

Plasmid

#232032

Purpose

in vitro transcription of murine Sra1

Depositor

Primo Schaer

Article

Richina et al Cell Mol Life Sci. 2025 Nov 25. doi: 10.

Insert

Sra1 (Sra1 Mouse)

Use

In vitro transcription

Promoter

T7

Available Since

Nov. 26, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pGEM-3zf(+)_hsSRA1

Plasmid

#232033

Purpose

in vitro transcription of human Sra1

Depositor

Primo Schaer

Article

Richina et al Cell Mol Life Sci. 2025 Nov 25. doi: 10.

Insert

Sra1 (SRA1 Human)

Use

In vitro transcription

Promoter

T7

Available Since

Nov. 26, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
XLone-UCE intron 3' deletion

Plasmid

#242182

Purpose

Express doxycycline inducible UCE intron 3' deletion of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE intron with 3' deletion (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 22, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
XLone-Unspliced CRNDE

Plasmid

#242177

Purpose

Express doxycycline inducible Unspliced CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

Unspliced CRNDE (CRNDE Human)

Expression

Mammalian

Mutation

PAM mutation (CCT to GTT)

Promoter

TRE3GS

Available Since

Aug. 22, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
XLone-UCE intron

Plasmid

#242180

Purpose

Express doxycycline inducible UCE-containing intron of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE intron (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
XLone-UCE mutant

Plasmid

#242185

Purpose

Express doxycycline inducible UCE 32S binding mutation of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE mutant (CRNDE Human)

Expression

Mammalian

Mutation

ATTTTCATGGGC to TAAAAGTACCCG

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
XLone-UCE

Plasmid

#242184

Purpose

Express doxycycline inducible UCE intron of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
XLone-UCE intron 5' deletion

Plasmid

#242181

Purpose

Express doxycycline inducible UCE intron 5' deletion of CRNDE in mammalian cells

Depositor

Joshua Mendell

Article

Lee et al Mol Cell. 2025 Apr 17;85(8):1543-1560.e1

Insert

CRNDE UCE intron with 5' deletion (CRNDE Human)

Expression

Mammalian

Promoter

TRE3GS

Available Since

Aug. 20, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE2-TetO-SOX17WT

Plasmid

#216176

Purpose

Generate lentiviruses encoding for wild-type SOX17

Depositor

Ralf Jauch

Article

Ho et al Stem Cell Reports. 2025 Mar 11;20(3):102

Insert

SOX17 (SOX17 Human)

Use

Lentiviral

Mutation

Glu113Glu (silent mutation); Glu120Glu (silent mu…

Available Since

July 2, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
Tau BA 12->10 V393I

Plasmid

#203390

Purpose

For transfection and in vitro assay

Depositor

Stefan Stamm

Article

Margvelani et al Biochim Biophys Acta Mol Basis Dis. 2024

Insert

MAPT (MAPT Human)

Expression

Mammalian

Mutation

V363I

Promoter

CMVf

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge
Tau BA 12->10 K369I

Plasmid

#203391

Purpose

For transfection and in vitro assay

Depositor

Stefan Stamm

Article

Margvelani et al Biochim Biophys Acta Mol Basis Dis. 2024

Insert

MAPT (MAPT Human)

Expression

Mammalian

Mutation

K369I

Promoter

CMVf

Available Since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

Enlarge

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