We narrowed to 407 results for: SAM activators

1. pYJ32-lenti-U6-MAFA-acti-gRNA3-MS2

   Plasmid

   #131075

   Purpose

   Activation of Mafa via SAM system

   Depositor

   Xiaojun Lian

   Insert

   MAFA activation gRNA3 (MAFA Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Oct. 3, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAct:dCas9-VP64

   Plasmid

   #78901

   Purpose

   Expresses dCas9-VP64 under actin promoter for SAM CRISPRa in Drosophila cells

   Depositor

   Norbert Perrimon

   Article

   Chavez et al Nat Methods. 2016 May 23. doi: 10.1038/n

   Insert

   dCas9-VP64
   

   Use

   CRISPR

   Expression

   Insect

   Promoter

   pActin (Drosophila)

   Available Since

   Oct. 11, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. pZR158_Lenti-U6-gRNA-10xCS1-PP7_hPGK-PCP-P65-HSF1-Puro

   Plasmid

   #180273

   Purpose

   Lentiviral expression vector for CRISPRa-SAM sgRNA with 10x capture sequence, and PCP-P65-HSF1 cassette

   Depositor

   Alexander Marson

   Article

   Schmidt et al Science. 2022 Feb 4;375(6580):eabj4008.

   Type

   Empty backbone

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Feb. 11, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pET23b-proMMP-7

   Plasmid

   #29524

   Depositor

   William Parks

   Article

   Ra et al J Biol Chem. 2009 Oct 9. 284(41):27924-3

   Insert

   proMMP-7 (MMP7 Human)
   

   Expression

   Bacterial

   Available Since

   April 29, 2011

   Availability

   Academic Institutions and Nonprofits only

5. pET23b-proMMP-7-E215Q

   Plasmid

   #29642

   Depositor

   William Parks

   Article

   Ra et al J Biol Chem. 2009 Oct 9. 284(41):27924-3

   Insert

   proMMP-7 (MMP7 Human)
   

   Expression

   Bacterial

   Mutation

   E215Q Catalytically Inactive

   Available Since

   April 29, 2011

   Availability

   Academic Institutions and Nonprofits only

6. pAct:MS2-p65-HSF

   Plasmid

   #78902

   Purpose

   Expresses MS2-p65-HSF under actin promoter for SAM CRISPRa in Drosophila cells

   Depositor

   Norbert Perrimon

   Article

   Chavez et al Nat Methods. 2016 May 23. doi: 10.1038/n

   Insert

   MS2-p65-HSF
   

   Use

   CRISPR

   Expression

   Insect

   Promoter

   pActin (Drosophila)

   Available Since

   Sept. 21, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. pWJ66

   Plasmid

   #46570

   Purpose

   Same as pdCas9, but with the dCas9-w fusion (w is fused at the C-terminal end of dCas9)

   Depositor

   Luciano Marraffini

   Article

   Bikard et al Nucleic Acids Res. 2013 Jun 12.

   Inserts

   tracrRNA
   dcas9-w
   CRISPR array
   

   Use

   CRISPR

   Tags

   rpoZ

   Expression

   Bacterial

   Mutation

   D10A, H840A

   Available Since

   Aug. 20, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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8. pWJ68

   Plasmid

   #46571

   Purpose

   Same as pdCas9, but with the w-dCas9 fusion (w is fused at the N-terminal end of dCas9)

   Depositor

   Luciano Marraffini

   Article

   Bikard et al Nucleic Acids Res. 2013 Jun 12.

   Inserts

   tracrRNA
   w-dcas9
   CRISPR array
   

   Use

   CRISPR

   Tags

   rpoZ

   Expression

   Bacterial

   Mutation

   D10A, H840A

   Available Since

   Aug. 27, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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9. pUC57 β-Globin

   Plasmid

   #194437

   Purpose

   In Situ hybridization probes

   Depositor

   Christopher Sansam

   Article

   Masser et al eLife 2023 (Reviewed Preprint) 12:RP8767

   Insert

   β-globin
   

   Use

   In situ hybridization

   Available Since

   Jan. 13, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA3-ABKAR

    Plasmid

    #140051

    Purpose

    Genetically encoded FRET-based biosensor for monitoring AMPK activity. Also sensitive to phosphorylation by BRSK1/2 when expressed in neurons.

    Depositor

    Jin Zhang

    Article

    Sample et al Mol Biol Cell. 2015 May 15;26(10):1935-4

    Insert

    ABKAR
    

    Tags

    6xHIS - T7 tag (gene 10 leader) - Xpress (TM) tag…

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 30, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCS2TAL3-RR-zrif1_exon8

    Plasmid

    #194434

    Purpose

    Right (RR) TALEN for mutating zebrafish rif1 gene

    Depositor

    Christopher Sansam

    Article

    Masser et al eLife 2023 (Reviewed Preprint) 12:RP8767

    Insert

    zrif1_ex8_RIGHT (rif1 Zebrafish)
    

    Use

    TALEN

    Promoter

    CMV IE94

    Available Since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCS2TAL3-DD-zrif1_exon8

    Plasmid

    #194435

    Purpose

    Left (DD) TALEN for mutating zebrafish rif1 gene

    Depositor

    Christopher Sansam

    Article

    Masser et al eLife 2023 (Reviewed Preprint) 12:RP8767

    Insert

    zrif1_ex8_LEFT (rif1 Zebrafish)
    

    Use

    TALEN

    Promoter

    CMV IE94

    Available Since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pUC57-GATA1

    Plasmid

    #194436

    Purpose

    In Situ hybridization probes

    Depositor

    Christopher Sansam

    Article

    Masser et al eLife 2023 (Reviewed Preprint) 12:RP8767

    Insert

    GATA1a (gata1a Zebrafish)
    

    Use

    In situ hybridization

    Available Since

    Jan. 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pYJ33-lenti-U6-Oct4-PE-acti-gRNA-DsRed

    Plasmid

    #131076

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    OCT4 proximal enhancer gRNA (POU5F1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCRISPRa_all-in-one

    Plasmid

    #183695

    Purpose

    Expresses CRISPRa components including dCas9-VP64, Synergistic Activation Mediators (SAM), mCherry, and gRNA expression cassette, blasticidin selective

    Depositor

    Edward Avezov

    Article

    Melo et al Nat Commun. 2022 May 6;13(1):2501. doi:

    Type

    Empty backbone

    Use

    CRISPR

    Available Since

    April 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pZR043_Lenti-U6-sgEGFR-MS2-PP7-hPGK-PCP-p65-HSF1-Puro

    Plasmid

    #180267

    Purpose

    Lentiviral expression vector for CRISPRa-SAM with EGFR targeting sgRNA

    Depositor

    Alexander Marson

    Article

    Schmidt et al Science. 2022 Feb 4;375(6580):eabj4008.

    Insert

    EGFR sgRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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17. pZR040_Lenti-U6-sgCtrl-MS2-PP7-hPGK-PCP-p65-HSF1-Puro

    Plasmid

    #180266

    Purpose

    Lentiviral expression vector for CRISPRa-SAM with non-targeting control sgRNA

    Depositor

    Alexander Marson

    Article

    Schmidt et al Science. 2022 Feb 4;375(6580):eabj4008.

    Insert

    No-Target Control sgRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pZR047_Lenti-U6-sgGARP-MS2-PP7-hPGK-PCP-p65-HSF1-Puro

    Plasmid

    #180268

    Purpose

    Lentiviral expression vector for CRISPRa-SAM with GARP targeting sgRNA

    Depositor

    Alexander Marson

    Article

    Schmidt et al Science. 2022 Feb 4;375(6580):eabj4008.

    Insert

    GARP sgRNA
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCAG MCP-VP64

    Plasmid

    #92357

    Purpose

    CAG-driven ubiquitous expression of MCP-VP64. MCP is bacteriophage MS2 coat protein, VP64 is transcriptional activation domain. Part of SAM-mediated gene activation system in chicken embryos.

    Depositor

    Tatjana Sauka-Spengler

    Article

    Williams et al Development. 2018 Feb 23;145(4). pii: de

    Insert

    MCP-VP64
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    Aug. 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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20. Raichu-OsRac1 CA

    Plasmid

    #133264

    Purpose

    Constitutively-active (CA) mutant of OsRac1; Acts as a positive control for small GTPases activation assays.

    Depositor

    Yoji Kawano

    Article

    Wong et al Plant Methods. 2018 Jul 7;14:56. doi: 10

    Insert

    OsRac1(G19V) (LOC4325879 Oryza sativa)
    

    Tags

    CFP-lipid and Venus-CRIB

    Expression

    Plant

    Mutation

    OsRac1 G19V

    Promoter

    Ubi

    Available Since

    Jan. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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