We narrowed to 1,034 results for: sri

1. pKHH030_sgAMBRA1#2

   Plasmid

   #174147

   Purpose

   Lentiviral vector expressing a sgRNA against the human AMBRA1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA (AMBRA1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pKHH030_sgAMBRA1#1

   Plasmid

   #174146

   Purpose

   Lentiviral vector expressing a sgRNA against the human AMBRA1 gene

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA (AMBRA1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pCG_SARS-CoV2/bat-CoV RaTG13 E C-V5-tag

   Plasmid

   #179977

   Purpose

   Mammalian expression vector for SARS-CoV-2 E or bat RaTG13 E, V5-tagged (SARS-CoV-2 E and RaTG13 E have the same amino acid sequence and codon optimized sequence).

   Depositor

   Konstantin Sparrer

   Article

   Hayn et al Cell Rep. 2021 May 18;35(7):109126.

   Insert

   SARS-CoV-2 E (E Synthetic)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   human codon-optimized

   Promoter

   Available since

   Feb. 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pPB-AMBRA1-501*-3xFLAG

   Plasmid

   #174160

   Purpose

   PiggyBac vector to stably express 3xFLAG-tagged AMBRA1 truncated at amino acid 501

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA1 (AMBRA1 Human)
   

   Use

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Missing aa 501-1208

   Promoter

   EF1A

   Available since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pPB-AMBRA1-217*-3xFLAG

   Plasmid

   #174161

   Purpose

   PiggyBac vector to stably express 3xFLAG-tagged AMBRA1 truncated at amino acid 217

   Depositor

   Julien Sage

   Article

   Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

   Insert

   AMBRA1 (AMBRA1 Human)
   

   Use

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Missing aa 217-1208

   Promoter

   EF1A

   Available since

   Sept. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. KRD9_HBA1(HBA1reg-HBB)

   Plasmid

   #232402

   Purpose

   AAV production plasmid for HBA1 UTRs vector from Fig. 3 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank HBA1 cassette. HAs are ~400bp each.

   Depositor

   Kyle Cromer, Matthew Porteus

   Article

   Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

   Insert

   Hemoglobin Subunit Alpha 1 (HBA1 Human)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. KRD2_HBA1(HBA1reg-UbC-GFP)

   Plasmid

   #232401

   Purpose

   AAV production plasmid for HBA1 WGR vector from Fig. 1 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBA1 UTRs flank UbC-GFP cassette; GFP is followed by BGH polyA. HAs are ~400bp each.

   Depositor

   Kyle Cromer, Matthew Porteus

   Article

   Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

   Insert

   Hemoglobin Subunit Alpha 1 (HBA1 Human)
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Feb. 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. Nav1.5_1-2linker411-717_PPSYtoAASA1960-1996

   Plasmid

   #187732

   Purpose

   Express a chimera of the Nav1.5 linker between the first and second transmembrane domain with the motif surrounding PPSY; residues 1974-1977 PPSY mutated to AASA

   Depositor

   Sandra Gabelli

   Article

   Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi

   Insert

   Nav1.5 1,2linker residues 411-717 and Nav1.5 residues 1960-1996 PPSY mutated to AASA (SCN5A Human)
   

   Use

   Tags

   His-TEV

   Expression

   Bacterial

   Mutation

   deletion of residues 1-410 and 718-1959 and 1997-…

   Promoter

   Available since

   Oct. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pCW-codon optimized catalytically inactive PHGDH

   Plasmid

   #154903

   Purpose

   Expresses codon optimized catalytically inactive PHGDH in mammalian cells

   Depositor

   Michael Pacold

   Article

   Ngo et al Cancer Discov. 2020 Sep;10(9):1352-1373.

   Insert

   Phosphoglycerate dehydrogenase (PHGDH Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Three mutations: D175N, R236K, H283A

   Promoter

   TRE

   Available since

   July 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. KRD22_HBA1(HBA1reg-HBB-longHAs)

    Plasmid

    #232403

    Purpose

    AAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bp

    Depositor

    Kyle Cromer, Matthew Porteus

    Article

    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10

    Inserts

    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Human Hemoglobin Subunit Beta (HBB Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    April 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge