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Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Pooled Library

#119977

Purpose

Designed for genomic deletion screening of functional lncRNAs by targeting their splice sites.

Depositor

Wensheng Wei

Article

Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

March 27, 2019

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (NEDD4 WW2 domain)

Pooled Library

#111707

Purpose

Encodes NEDD4 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available Since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (14-3-3σ)

Pooled Library

#111706

Purpose

Encodes 14-3-3σ and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available Since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (14-3-3β)

Pooled Library

#111705

Purpose

Encodes 14-3-3β and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available Since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

Pooled Library

#89640

Purpose

Designed for genomic deletion screening of functional lncRNAs (long non-coding RNAs) using lentiviral pgRNAs (paired-guide RNAs).

Depositor

Wensheng Wei

Article

Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

Expression

Mammalian

Use

Lentiviral

Available Since

May 17, 2017

Availability

Academic Institutions and Nonprofits only
Mode #2 Library (NEDD4-2 WW2 domain)

Pooled Library

#111708

Purpose

Encodes NEDD4-2 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available Since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

Pooled Library

#223064

Purpose

Knockout library to carry out genome-scale optical screening using Nuclear In-Situ Sequencing (NIS-Seq).

Depositor

Jonathan Schmid-Burgk

Article

Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

May 23, 2025

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library B

Pooled Library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Cherry Brie Pooled Library

Pooled Library

#170511

Purpose

Genome-wide knockout library. It is identical to the Brie library #73633, replacing Puromycin resistance with mCherry.

Depositor

Pavel Tolar

Article

Newman et al biorXiv 2021.03.02.433398

Expression

Mammalian

Species

Synthetic

Use

CRISPR and Lentiviral

Available Since

Sept. 9, 2021

Availability

Academic Institutions and Nonprofits only
pEPIP_PepTile_40merFragments_65CancerDrivers

Pooled Library

#172109

Purpose

Lentiviral peptide expression library for overexpression fitness screening

Depositor

Prashant Mali

Article

Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

Use

Lentiviral

Available Since

Oct. 21, 2021

Availability

Academic Institutions and Nonprofits only
Yeast Inducible CRISPRi Library

Pooled Library

#161829

Purpose

Inducible genome-wide CRISPRi library targeting S. cerevisiae genes with 6-12 guide RNAs per gene.

Depositor

Saeed Tavazoie

Article

Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available Since

April 28, 2021

Availability

Academic Institutions and Nonprofits only
LV2btCRISPRko.v1

Pooled Library

#213927

Purpose

Uses lentivirus to deliver the library into hard-to-transduce cells

Depositor

Wenfang Spring Tan

Article

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
PBbtCRISPRko.v1

Pooled Library

#213928

Purpose

Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

Depositor

Wenfang Spring Tan

Article

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
Mode #1 Library

Pooled Library

#111704

Purpose

Encodes GST-fused human phosphopeptides

Depositor

Jesse Rinehart

Article

Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

Expression

Bacterial

Species

Homo sapiens

Available Since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
StopPR epegRNA library (lAC002)

Pooled Library

#227706

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available Since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only
Lourido Toxoplasma CRISPR Library V1

Pooled Library

#80636

Purpose

Knockout library targeting 8,158 predicted protein-coding gene in Toxoplasma gondii.

Depositor

Sebastian Lourido

Article

Sidik et al Cell. 2016 Sep 8;166(6):1423-1435.e12. d

Available Since

Sept. 19, 2016

Availability

Academic Institutions and Nonprofits only
Pan-cancer CasRx lncRNA Albarossa library

Pooled Library

#212966

Purpose

Genome-scale library for pan-cancer interrogation of lncRNA dependencies using CasRx.

Depositor

Roland Rad

Article

Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 21, 2024

Availability

Academic Institutions and Nonprofits only
lenti_LTC_v2

Pooled Library

#238548

Purpose

Lentiviral expression of the ~2000 member library of v2 lineage tracing cassettes

Depositor

Jonathan Weissman

Article

Koblan et al Science. 2025 Jul 24:eadx3800. doi: 10.1

Expression

Mammalian

Use

Lentiviral

Available Since

Aug. 8, 2025

Availability

Academic Institutions and Nonprofits only
Self-targeting epegRNA library, +5 G>H (lDS004)

Pooled Library

#227707

Purpose

CRISPR guide RNA library for prime editing

Depositor

Brittany Adamson

Article

Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

Expression

Mammalian

Use

Lentiviral

Available Since

Jan. 23, 2025

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 54 results

Results per page:

Sort results by:

More Filters

We narrowed to 54 results for: p

Splicing-targeting CRISPR-Cas9 library for human lncRNAs

Mode #2 Library (NEDD4 WW2 domain)

Mode #2 Library (14-3-3σ)

Mode #2 Library (14-3-3β)

Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

Mode #2 Library (NEDD4-2 WW2 domain)

CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

Liu Lab MusCK Library A

Liu Lab MusCK Library B

Mouse Cherry Brie Pooled Library

pEPIP_PepTile_40merFragments_65CancerDrivers

Yeast Inducible CRISPRi Library

LV2btCRISPRko.v1

PBbtCRISPRko.v1

Mode #1 Library

StopPR epegRNA library (lAC002)

Lourido Toxoplasma CRISPR Library V1

Pan-cancer CasRx lncRNA Albarossa library

lenti_LTC_v2

Self-targeting epegRNA library, +5 G>H (lDS004)

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