We narrowed to 131 results for: %s

#247028

Enriched for effective guides through prioritization of guides with strong on-target activity. Designed against current gene annotations, offering coverage of the contemporary mouse genome.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#90294

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Jason Moffat

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

May 5, 2017

Academic Institutions and Nonprofits only

#206249

The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#206248

The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#79153

Library of protospacer flanking sites (PFS) inserted at the 5' end of the β-lactamase gene for screening PFS preference for Cas13a/C2c2.

Feng Zhang

Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

Oct. 26, 2017

Academic Institutions and Nonprofits only

#236783

A genome-wide loss-of-function CRISPR base editing library designed to introduce STOP codons within the first 50% of coding sequences in the genome of Leishmania mexicana.

Tom Beneke

Arias del Angel et al bioRxiv 2025.06.16.659792

April 1, 2026

Academic Institutions and Nonprofits only

#183825

Paired gRNA library targeting genes related to B-cell to macrophage transdifferentiation.

Roderic Guigo

Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

Aug. 25, 2022

Academic Institutions and Nonprofits only

#226117

Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).

Rui Lu

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Oct. 29, 2024

Academic Institutions and Nonprofits only

#161829

Inducible genome-wide CRISPRi library targeting S. cerevisiae genes with 6-12 guide RNAs per gene.

Saeed Tavazoie

Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

April 28, 2021

Academic Institutions and Nonprofits only

#224585

Pyrrolysine tRNA synthetase library to generate new genetic code expansion (GCE) systems for site-specific incorporation of non-canonical amino acids (ncAAs) into proteins.

Ryan Mehl

Avila-Crump et al ACS Chem Biol. 2022 Dec 16;17(12):3458-3

Jan. 6, 2025

Academic Institutions and Nonprofits only

#171531

Knockout library targeting ubiquitination and de-ubiquitination complex genes.

Chunliang Li

Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

June 22, 2021

Academic Institutions and Nonprofits only

#122131

Increases transcriptional repression of genes encoding transcription factors in combination with dCas9 repression systems, such as the dCas9-KRAB system.

Stanley Qi

Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

April 25, 2019

Academic Institutions and Nonprofits only

#232068

The CRASP-Seq backbone is designed to accommodate the cloning of diverse gRNA libraries. It includes a cell barcode (CBC), which enhances its functionality by enabling library preparation.

Thomas Gonatopoulos-Pournatzis

Behera et al Mol Cell. 2026 Jan 8;86(1):41-59.e15. do

Oct. 28, 2025

Academic Institutions and Nonprofits only

#232070

Tiling library to conduct CRASP-Seq experiments combined with high-throughput base editing for precise and scalable investigations into protein regions that affect splicing regulation.

Thomas Gonatopoulos-Pournatzis

Behera et al Mol Cell. 2026 Jan 8;86(1):41-59.e15. do

Oct. 28, 2025

Academic Institutions and Nonprofits only

#162256

Knockout library that targets human epigenetic genes.

Kivanc Birsoy

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Nov. 17, 2020

Academic Institutions and Nonprofits only

#200011

Knockout library targeting a comprehensive set of mouse genes with annotated function as chromatin regulators.

Bradley Bernstein, Gabriel Griffin, Robert Manguso

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Dec. 15, 2023

Academic Institutions and Nonprofits only

#179851

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

Jason Moffat

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

May 12, 2022

Academic Institutions and Nonprofits only

#179852

Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

Jason Moffat

Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

May 12, 2022

Academic Institutions and Nonprofits only

#67989

Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Kosuke Yusa

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Oct. 14, 2016

Academic Institutions and Nonprofits only

#67988

Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Kosuke Yusa

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Oct. 14, 2016

Academic Institutions and Nonprofits only