We narrowed to 35 results for: des.1

1. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set B

   Pooled Library

   #104091

   Purpose

   Crispri

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Use

   Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

2. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92383

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

3. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

   Pooled Library

   #92384

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

4. Human CRISPR Poison Exon Knockout Library

   Pooled Library

   #138084

   Purpose

   The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

   Depositor

   Robert Bradley

   Article

   Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   March 6, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Human Whole Genome sgRNA iBAR Library

   Pooled Library

   #140633

   Purpose

   CRISPR pooled screen at high MOI by the embedded internal barcodes

   Depositor

   Wensheng Wei

   Article

   Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

   Use

   CRISPR and Lentiviral

   Available since

   April 21, 2020

   Availability

   Academic Institutions and Nonprofits only

6. Green monkey (Chlorocebus sabaeus) sgRNA library

   Pooled Library

   #178284

   Purpose

   Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

   Depositor

   John Doench, David Root

   Article

   Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

   Expression

   Mammalian

   Species

   Chlorocebus sabaeus (african green monkey)

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 23, 2021

   Availability

   Academic Institutions and Nonprofits only

7. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

8. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

9. Barcode Library 0 (BCL0)

   Pooled Library

   #179851

   Purpose

   Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

   Depositor

   Jason Moffat

   Article

   Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

10. Mouse sphingolipid metabolism knockout library

    Pooled Library

    #206249

    Purpose

    The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

11. MinLibCas9

    Pooled Library

    #164896

    Purpose

    Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

    Depositor

    Mathew Garnett

    Article

    Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 20, 2021

    Availability

    Academic Institutions and Nonprofits only

12. LibTest

    Pooled Library

    #113147

    Purpose

    Customized sgRNA library targeting 86 E. coli genes

    Depositor

    Chong Zhang

    Article

    Guo et al Nucleic Acids Res. 2018 Aug 21;46(14):70

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

13. E.coli_GW-sgRNA_Lib5

    Pooled Library

    #113138

    Purpose

    Genome-wide gRNA library for E. coli, sub5

    Depositor

    Chong Zhang

    Article

    Guo et al Nucleic Acids Res. 2018 Aug 21;46(14):70

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

14. pMuSIC pool v1.0

    Pooled Library

    #227193

    Purpose

    Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

    Depositor

    Marc Birtwistle

    Article

    Lu et al ACS Synth Biol. 2025 May 16;14(5):1533-1

    Expression

    Mammalian

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

15. Humagne Set C

    Pooled Library

    #172650

    Purpose

    Set C contains best-ranked guides 1 and 4.

    Depositor

    John Doench, David Root

    Article

    DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

    Expression

    Mammalian

    Available since

    Nov. 10, 2021

    Availability

    Academic Institutions and Nonprofits only