We narrowed to 172 results for: ide

1. Oxford Drosophila melanogaster Genome-wide CRISPR Library

   Pooled Library

   #64750

   Purpose

   Library designed for genomic targeting and screening in Drosophila cells. All possible gRNA target sites within the shared exonic regions on either DNA strand of the Drosophila genome were computed.

   Depositor

   Ji-Long Liu

   Article

   Bassett et al J Genet Genomics. 2015 Jun 20;42(6):301-

   Expression

   Insect

   Species

   Drosophila melanogaster, Streptococcus pyogenes, and Synthetic

   Use

   CRISPR

   Available Since

   March 7, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

   Pooled Library

   #1000000083

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human kinome

   Depositor

   John Doench, David Root

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Human genome-wide lentiviral CRISPR gRNA library version 1

   Pooled Library

   #67989

   Purpose

   Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

   Depositor

   Kosuke Yusa

   Article

   Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

   Species

   Homo sapiens, Mus musculus, and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Mouse genome-wide lentiviral CRISPR gRNA library version 2

   Pooled Library

   #67988

   Purpose

   Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

   Depositor

   Kosuke Yusa

   Article

   Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

   Species

   Homo sapiens, Mus musculus, and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

5. Human Brunello kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75314

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

   Pooled Library

   #75317

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

7. Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

   Pooled Library

   #75315

   Purpose

   Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

8. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

9. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

10. Mini-human AsCpf1-based human genome-wide knockout library

    Pooled Library

    #130630

    Purpose

    Knockout library targeting 16,977 genes. Each gene is targeted by an AsCpf1(AsCas12a)-based array containing 3-4 guides concatenated in one vector.

    Depositor

    Giulio Draetta

    Article

    Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 9, 2019

    Availability

    Academic Institutions and Nonprofits only

11. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

    Pooled Library

    #1000000100

    Purpose

    CRISPR gRNA knockout pooled library (version 1) for targeting the human genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

12. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000096

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

13. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

    Pooled Library

    #1000000095

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Eric Lander, David Sabatini

    Available Since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

14. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

    Pooled Library

    #89640

    Purpose

    Designed for genomic deletion screening of functional lncRNAs (long non-coding RNAs) using lentiviral pgRNAs (paired-guide RNAs).

    Depositor

    Wensheng Wei

    Article

    Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    May 17, 2017

    Availability

    Academic Institutions and Nonprofits only

15. Mouse Cherry Brie Pooled Library

    Pooled Library

    #170511

    Purpose

    Genome-wide knockout library. It is identical to the Brie library #73633, replacing Puromycin resistance with mCherry.

    Depositor

    Pavel Tolar

    Article

    Newman et al biorXiv 2021.03.02.433398

    Expression

    Mammalian

    Species

    Synthetic

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 9, 2021

    Availability

    Academic Institutions and Nonprofits only

16. Mode #2 Library (14-3-3σ)

    Pooled Library

    #111706

    Purpose

    Encodes 14-3-3σ and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Mode #2 Library (14-3-3β)

    Pooled Library

    #111705

    Purpose

    Encodes 14-3-3β and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

18. Mode #1 Library

    Pooled Library

    #111704

    Purpose

    Encodes GST-fused human phosphopeptides

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

19. Mode #2 Library (NEDD4-2 WW2 domain)

    Pooled Library

    #111708

    Purpose

    Encodes NEDD4-2 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

20. Mode #2 Library (NEDD4 WW2 domain)

    Pooled Library

    #111707

    Purpose

    Encodes NEDD4 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

    Depositor

    Jesse Rinehart

    Article

    Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

    Expression

    Bacterial

    Species

    Homo sapiens

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only