375 results

1. Mouse Base Editing Sensor Library

   Pooled Library

   #179217

   Purpose

   sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

   Depositor

   Lukas Dow

   Article

   Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   June 16, 2022

   Availability

   Academic Institutions and Nonprofits only

2. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Eric Lander, David Sabatini

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

3. pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

   Pooled Library

   #199601

   Purpose

   pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

   Depositor

   George Church

   Article

   Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

   Expression

   Mammalian

   Species

   Aav2

   Use

   AAV

   Available since

   June 13, 2023

   Availability

   Academic Institutions and Nonprofits only

4. hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/gene

   Pooled Library

   #83986

   Purpose

   Human CRISPRa Pooled Library targeting unassigned genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

5. Human lentiviral CRISPR library_v1

   Pooled Library

   #69763

   Purpose

   Genome-scale sgRNA screening library in lentiviral vector pLB, targeting 20,121 human protein-coding genes

   Depositor

   Haoquan Wu

   Article

   Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

   Pooled Library

   #86538

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

7. mCRISPRa-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

   Pooled Library

   #84001

   Purpose

   Mouse CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

8. mCRISPRa-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

   Pooled Library

   #84000

   Purpose

   Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

9. hCRISPRi-v2, Cancer and Apoptosis (h2), top 5 sgRNAs/gene

   Pooled Library

   #83972

   Purpose

   Human CRISPRi Pooled Library targeting cancer and apoptosis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Human Lentiviral sgRNA Library - Control

    Pooled Library

    #51048

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only