390 results

1. hCRISPRi_dual_3_4

   Pooled Library

   #187247

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Jonathan Weissman, Marco Jost

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available Since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

2. p11-3’_8xN_PAM-site2 (RTW555)

   Pooled Library

   #160133

   Purpose

   Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

   Depositor

   Keith Joung, Benjamin Kleinstiver

   Article

   Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

   Species

   Synthetic

   Use

   CRISPR

   Available Since

   Feb. 8, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

   Pooled Library

   #138015

   Purpose

   This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

   Depositor

   William Pu

   Article

   VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

   Species

   Mus musculus

   Use

   AAV, CRISPR, and Cre/Lox

   Available Since

   April 17, 2020

   Availability

   Academic Institutions and Nonprofits only

4. SARS-CoV-2 RBD XBB.1.5 SSM Library

   Pooled Library

   #1000000232

   Depositor

   Tyler Starr

   Available Since

   Oct. 25, 2023

   Availability

   Academic Institutions and Nonprofits only

5. Sctrans-PP

   Pooled Library

   #153101

   Purpose

   CRISPR library targets all non-essential and conditionally essential transporter genes in S. cerevisiae

   Depositor

   Irina Borodina

   Article

   Wang et al Metab Eng. 2021 Jan 16. pii: S1096-7176(

   Expression

   Yeast

   Species

   Saccharomyces cerevisiae

   Use

   CRISPR

   Available Since

   Jan. 20, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Human Genome-wide Intron Tagging Library, Frame 1

   Pooled Library

   #216134

   Purpose

   Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

   Depositor

   Stefan Kubicek

   Article

   Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

7. Human Genome-wide Intron Tagging Library, Frame 0

   Pooled Library

   #216133

   Purpose

   Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

   Depositor

   Stefan Kubicek

   Article

   Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

8. CRISPRi non-coding library (CRiNCL) - Unique to iPSC

   Pooled Library

   #86540

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available Since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

9. scQers promoter control series (p027, p028, p029, p041, p042)

   Pooled Library

   #1000000239

   Depositor

   Jay Shendure

   Available Since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

10. Human Transporter Knockout Library with UMIs

    Pooled Library

    #221409

    Purpose

    gRNA library to test the impact of transporters on biological processes

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only