Addgene

374 results

Showing: 41 - 60 of 374 results

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pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

Pooled Library

#104861

Depositor

Sarah Teichmann

Article

Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

Available since

Sept. 9, 2019

Availability

Academic Institutions and Nonprofits only
Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Pooled Library

#92380

Purpose

CRISPRa

Depositor

David Root, John Doench

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

Aug. 3, 2017

Availability

Academic Institutions and Nonprofits only
Human SAM library in lentiSAMv2 backbone

Pooled Library

#1000000078

Purpose

Genome-wide CRISPR gRNA pooled library for activation of human genes

Depositor

Feng Zhang

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

Pooled Library

#1000000053

Purpose

CRISPR gRNA knockout pooled library for targeting the mouse genome

Depositor

Feng Zhang

Available since

July 23, 2014

Availability

Academic Institutions and Nonprofits only
hCRISPRi_dual_1_2

Pooled Library

#187246

Purpose

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Depositor

Jonathan Weissman, Marco Jost

Article

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Species

Synthetic

Use

Lentiviral

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only
Glycogene CRISPR Library

Pooled Library

#140961

Purpose

Targets human genes involved in cellular glycosylation.

Depositor

Sriram Neelamegham

Article

Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

Sept. 9, 2020

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_2

Pooled Library

#134583

Purpose

Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
Mouse metabolism knockout library

Pooled Library

#160129

Purpose

CRISPR library targets mouse metabolic genes

Depositor

Kivanc Birsoy

Article

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available since

Nov. 10, 2020

Availability

Academic Institutions and Nonprofits only
Mouse Chromatin Regulator Library

Pooled Library

#200011

Purpose

CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

Depositor

Robert Manguso, Gabriel Griffin, Bradley Bernstein

Article

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Dec. 15, 2023

Availability

Academic Institutions and Nonprofits only
Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

Pooled Library

#104090

Purpose

Crispri

Depositor

David Root, John Doench

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Watermelon

Pooled Library

#155257

Purpose

Lineage tracing library

Depositor

Joan Brugge, Aviv Regev

Article

Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

Expression

Mammalian

Use

Lentiviral

Available since

Oct. 15, 2021

Availability

Academic Institutions and Nonprofits only
Murine cell surface protein knockout (McspKO) library

Pooled Library

#200445

Purpose

A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene

Depositor

Junjie Chen

Article

Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

Expression

Mammalian

Species

Mus musculus

Use

CRISPR, Lentiviral, and Mouse Targeting

Available since

Oct. 26, 2023

Availability

Academic Institutions and Nonprofits only
Humagne Set C

Pooled Library

#172650

Purpose

Set C contains best-ranked guides 1 and 4.

Depositor

David Root, John Doench

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
Humagne Set D

Pooled Library

#172651

Purpose

Set D contains best-ranked guides 2 and 3.

Depositor

David Root, John Doench

Article

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Expression

Mammalian

Available since

Nov. 10, 2021

Availability

Academic Institutions and Nonprofits only
pMuSIC pool v1.0

Pooled Library

#227193

Purpose

Two-way barcodes from 18 fluorescent proteins for mammalian expression. Can be used for clone tracing, or for pairing with perturbations for single cell resolution in spectral detection measurements.

Depositor

Marc Birtwistle

Article

Lu et al bioRxiv [Preprint]. 2024 Oct 24:2024.10.

Expression

Mammalian

Available since

Dec. 18, 2024

Availability

Academic Institutions and Nonprofits only
TRE-MPRA_minPromega Library

Pooled Library

#201013

Purpose

Massively parallel reporter assay (MPRA) library with minPromega promoter

Depositor

Justin English

Article

Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

Expression

Mammalian

Use

Luciferase

Available since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
psgRNA_EcoWG1

Pooled Library

#131625

Purpose

Improved genome-wide knockdown of E. coli genes

Depositor

David Bikard

Article

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

Expression

Bacterial

Species

Escherichia coli

Use

CRISPR

Available since

May 12, 2020

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

Pooled Library

#83976

Purpose

Human CRISPRi Pooled Library targeting membrane proteins

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
PB-EF1a-Puro-V8.2

Pooled Library

#178943

Purpose

Barcoding library for the macsGESTALT inducible lineage recording system

Depositor

Christopher Lengner

Article

Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

Expression

Mammalian

Available since

March 22, 2022

Availability

Academic Institutions and Nonprofits only
Green monkey (Chlorocebus sabaeus) sgRNA library

Pooled Library

#178284

Purpose

Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

Depositor

David Root, John Doench

Article

Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

Expression

Mammalian

Species

Chlorocebus sabaeus (african green monkey)

Use

CRISPR and Lentiviral

Available since

Nov. 23, 2021

Availability

Academic Institutions and Nonprofits only

Showing: 41 - 60 of 374 results

Results per page:

Sort results by:

pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

Human SAM library in lentiSAMv2 backbone

Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

hCRISPRi_dual_1_2

Glycogene CRISPR Library

Drosophila_sgRNA_group_2

Mouse metabolism knockout library

Mouse Chromatin Regulator Library

Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

Watermelon

Murine cell surface protein knockout (McspKO) library

Humagne Set C

Humagne Set D

pMuSIC pool v1.0

TRE-MPRA_minPromega Library

psgRNA_EcoWG1

hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

PB-EF1a-Puro-V8.2

Green monkey (Chlorocebus sabaeus) sgRNA library

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