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Human Whole Genome sgRNA iBAR Library

Pooled Library

#140633

Purpose

Enables genome-wide CRISPR screening at high MOI through use of barcoded gRNA plasmids.

Depositor

Wensheng Wei

Article

Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

Use

CRISPR and Lentiviral

Available Since

April 21, 2020

Availability

Academic Institutions and Nonprofits only
Human CRISPR Metabolic Gene Knockout Library

Pooled Library

#110066

Purpose

Targets 2,981 human metabolic genes with 29,790 guide RNAs. The library contains ~10 gRNAs per gene.

Depositor

David Sabatini

Article

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

Use

Lentiviral

Available Since

May 4, 2018

Availability

Academic Institutions and Nonprofits only
pC004 - PFS library in Beta-lactamase gene Target Plasmid

Pooled Library

#79153

Purpose

Library of protospacer flanking sites (PFS) inserted at the 5' end of the β-lactamase gene for screening PFS preference for Cas13a/C2c2.

Depositor

Feng Zhang

Article

Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

Available Since

Oct. 26, 2017

Availability

Academic Institutions and Nonprofits only
MORF library without GFP and mCherry controls

Pooled Library

#192821

Purpose

Barcoded transcription factor ORF library for high throughput screening

Depositor

Feng Zhang

Article

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available Since

Jan. 11, 2023

Availability

Academic Institutions and Nonprofits only
RNA-binding protein pooled CRISPR knockout library

Pooled Library

#141438

Purpose

Knockout library targeting RNA-binding proteins with 10 guide RNAs per target.

Depositor

Eugene Yeo

Article

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

May 28, 2020

Availability

Academic Institutions and Nonprofits only
Human Metabolic Gene CRISPRa sgRNA library

Pooled Library

#187080

Purpose

Library targeting 2,989 human metabolic genes for activation of gene expression.

Depositor

Kivanc Birsoy

Article

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available Since

Oct. 26, 2022

Availability

Academic Institutions and Nonprofits only
Mouse Metabolic Gene CRISPRa sgRNA library

Pooled Library

#187081

Purpose

Library targeting 2,989 mouse metabolic genes for activation of gene expression.

Depositor

Kivanc Birsoy

Article

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Expression

Mammalian

Species

Mus musculus

Use

Lentiviral

Available Since

Oct. 26, 2022

Availability

Academic Institutions and Nonprofits only
mTORC1 Focused library

Pooled Library

#164084

Purpose

Knockout library targeting human genes required for mTORC1 activation and inhibition.

Depositor

David Sabatini

Article

Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Jan. 11, 2021

Availability

Academic Institutions and Nonprofits only
Human Paralog Knockout Library (pgPEN)

Pooled Library

#171172

Purpose

Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

Depositor

Alice Berger

Article

Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

Expression

Mammalian

Species

Homo sapiens and Synthetic

Use

CRISPR and Lentiviral

Available Since

Sept. 28, 2021

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiCRISPRv2

Pooled Library

#73179

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiCRISPRv2

Pooled Library

#73632

Purpose

Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Human Epigenetic Knockout Library

Pooled Library

#162256

Purpose

Knockout library that targets human epigenetic genes.

Depositor

Kivanc Birsoy

Article

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Nov. 17, 2020

Availability

Academic Institutions and Nonprofits only
Mouse metabolism knockout library

Pooled Library

#160129

Purpose

Targets mouse metabolic genes and includes most metabolic enzymes and transporters.

Depositor

Kivanc Birsoy

Article

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Nov. 10, 2020

Availability

Academic Institutions and Nonprofits only
Human SLC SAM Library

Pooled Library

#132561

Purpose

Activation library targeting human SLC proteins.

Depositor

Giulio Superti-Furga

Article

Rebsamen et al Life Sci Alliance. 2022 Sep 16;5(11):e20

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

May 18, 2020

Availability

Academic Institutions and Nonprofits only
MYC-CRISPR

Pooled Library

#173195

Purpose

Knockout library targeting human E-boxes genome-wide.

Depositor

Agnieszka Dzikiewicz-Krawczyk

Article

Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Aug. 11, 2021

Availability

Academic Institutions and Nonprofits only
Human sgRNA library Brunello in lentiGuide-Puro

Pooled Library

#73178

Purpose

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
Mouse sgRNA library Brie in lentiGuide-Puro

Pooled Library

#73633

Purpose

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Has Service

Lentiviral Prep

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

Feb. 25, 2016

Availability

Academic Institutions and Nonprofits only
Human SLC KO Library

Pooled Library

#132552

Purpose

Knockout library targeting human SLC proteins.

Depositor

Giulio Superti-Furga

Article

Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut version 3 library (TKOv3)

Pooled Library

#90294

Purpose

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Depositor

Jason Moffat

Article

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

Available Since

May 5, 2017

Availability

Academic Institutions and Nonprofits only
Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

Pooled Library

#159392

Purpose

Mouse lentiviral genome-wide CRISPR library

Depositor

Jason Moffat

Article

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Nov. 9, 2020

Availability

Academic Institutions and Nonprofits only

Showing: 81 - 100 of 100 results

Results per page:

Sort results by:

More Filters

We narrowed to 100 results for: eng

Human Whole Genome sgRNA iBAR Library

Human CRISPR Metabolic Gene Knockout Library

pC004 - PFS library in Beta-lactamase gene Target Plasmid

MORF library without GFP and mCherry controls

RNA-binding protein pooled CRISPR knockout library

Human Metabolic Gene CRISPRa sgRNA library

Mouse Metabolic Gene CRISPRa sgRNA library

mTORC1 Focused library

Human Paralog Knockout Library (pgPEN)

Human sgRNA library Brunello in lentiCRISPRv2

Mouse sgRNA library Brie in lentiCRISPRv2

Human Epigenetic Knockout Library

Mouse metabolism knockout library

Human SLC SAM Library

MYC-CRISPR

Human sgRNA library Brunello in lentiGuide-Puro

Mouse sgRNA library Brie in lentiGuide-Puro

Human SLC KO Library

Toronto KnockOut version 3 library (TKOv3)

Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

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