We narrowed to 161 results for: lentiviral

1. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

2. The Human Druggable CRISPR library

   Pooled Library

   #200013

   Purpose

   The library contains ~10,000 sgRNAs targeting 1,980 human genes (5 sgRNAs per gene and 100 nontargeting control sgRNAs).

   Depositor

   Lianxin Liu

   Article

   Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 9, 2023

   Availability

   Academic Institutions and Nonprofits only

3. MORF library without GFP and mCherry controls

   Pooled Library

   #192821

   Purpose

   Barcoded transcription factor ORF library for high throughput screening

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Mouse lipid metabolism knockout library

   Pooled Library

   #206248

   Purpose

   The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

5. hCRISPRi_dual_1_2

   Pooled Library

   #187246

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Marco Jost, Jonathan Weissman

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

6. hCRISPRa_dual_1_2

   Pooled Library

   #187249

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Marco Jost, Jonathan Weissman

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

7. RNA-binding protein pooled CRISPR knockout library

   Pooled Library

   #141438

   Purpose

   CRISPR knockout library targets RBPs with 10 sgRNAs/gene

   Depositor

   Eugene Yeo

   Article

   Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   May 28, 2020

   Availability

   Academic Institutions and Nonprofits only

8. Human SLC overexpression library

   Pooled Library

   #213694

   Purpose

   Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Aug. 30, 2024

   Availability

   Academic Institutions and Nonprofits only

9. SPECS library

   Pooled Library

   #127842

   Purpose

   For performing high-throughput cell state-specific synthetic promoter screening

   Depositor

   Timothy Lu

   Article

   Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Aug. 22, 2020

   Availability

   Academic Institutions and Nonprofits only

10. Perturb-seq GBC library

    Pooled Library

    #85968

    Purpose

    Perturb-seq GBC library

    Depositor

    Jonathan Weissman

    Article

    Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 14, 2017

    Availability

    Academic Institutions and Nonprofits only

11. Splicing-targeting CRISPR-Cas9 library for human lncRNAs

    Pooled Library

    #119977

    Purpose

    The CRISPR sgRNA library was designed to target the 5' or 3' splice sites of lncRNAs in genome-scale, in order to knockout the targeted lncRNAs.

    Depositor

    Wensheng Wei

    Article

    Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    March 27, 2019

    Availability

    Academic Institutions and Nonprofits only

12. hCRISPRi_dual_5_6

    Pooled Library

    #187248

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

13. TBG-mTSG

    Pooled Library

    #113585

    Purpose

    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

    Depositor

    Sidi Chen

    Article

    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

    Expression

    Mammalian

    Use

    AAV, CRISPR, Lentiviral, and Luciferase

    Available since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only

14. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

15. hCRISPRi_dual_3_4

    Pooled Library

    #187247

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

16. Human Genome-wide Intron Tagging Library, Frame 1

    Pooled Library

    #216134

    Purpose

    Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

    Depositor

    Stefan Kubicek

    Article

    Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

17. Human Genome-wide Intron Tagging Library, Frame 0

    Pooled Library

    #216133

    Purpose

    Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

    Depositor

    Stefan Kubicek

    Article

    Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

18. hCRISPRa_dual_3_4

    Pooled Library

    #187250

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

19. hCRISPRa_dual_5_6

    Pooled Library

    #187251

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

20. Human ABC Transporter Knockout Sub-library with UMIs

    Pooled Library

    #221410

    Purpose

    gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only