We narrowed to 279 results for: Spr

1. CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

   Pooled Library

   #86538

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

2. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

3. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Rebecca Voorhees, Jonathan Weissman

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92379

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

   Pooled Library

   #92380

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Use

   Lentiviral

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

6. Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

   Pooled Library

   #101931

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92383

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

8. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

   Pooled Library

   #1000000126

   Purpose

   CRISPR gRNA mouse knockout pooled library - Trafficking, mitochondrial, and motility

   Depositor

   Michael Bassik

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

9. CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

   Pooled Library

   #86539

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

10. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92384

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

11. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136479

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #101927

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #1000000122

    Purpose

    CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

14. Human CRISPR lncRNA activation library (SAM) in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000106

    Purpose

    Human CRISPR Synergistic Activation Mediator (SAM) pooled library for the transcriptional activation of lncRNAs

    Depositor

    Feng Zhang

    Available since

    June 5, 2017

    Availability

    Academic Institutions and Nonprofits only

15. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

    Pooled Library

    #1000000100

    Purpose

    CRISPR gRNA knockout pooled library (version 1) for targeting the human genome

    Depositor

    Eric Lander, David Sabatini

    Available since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

16. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

17. Sabatini/Lander Lab Ras synthetic lethal candidate focused human sgRNA library in lentiCRISPRv1

    Pooled Library

    #92352

    Purpose

    contains 6,661 sgRNAs (comprising 499 intergenic control sgRNAs and 6,162 sgRNAs targeting 132 control and candidate Ras synthetic lethal genes at up to 50 sgRNAs per gene)

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

    Species

    Homo sapiens

    Available since

    June 7, 2017

    Availability

    Academic Institutions and Nonprofits only

18. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

    Pooled Library

    #89640

    Purpose

    Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

    Depositor

    Wensheng Wei

    Article

    Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 17, 2017

    Availability

    Academic Institutions and Nonprofits only

19. Human messenger-RBP sgRNA library

    Pooled Library

    #168791

    Purpose

    CRISPR library targets sub-pool of human mRNA binding proteins

    Depositor

    Martin Turner

    Article

    Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    July 30, 2021

    Availability

    Academic Institutions and Nonprofits only

20. DDR_MKOv4

    Pooled Library

    #140219

    Purpose

    CRISPR DNA damage response library

    Depositor

    Junjie Chen

    Article

    Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 20, 2021

    Availability

    Academic Institutions and Nonprofits only