We narrowed to 285 results for: Spr

#115927

~93,000 gRNAs targeting random positions along the genome of E. coli MG1655 with a NGG PAM motif. Contains ~19 targets per gene and can be used with SpdCas9 to perform pooled CRISPRi screens.

David Bikard

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

June 6, 2019

Academic Institutions and Nonprofits only

#140633

Enables genome-wide CRISPR screening at high MOI through use of barcoded gRNA plasmids.

Wensheng Wei

Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

April 21, 2020

Academic Institutions and Nonprofits only

#247027

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#160134

Plasmid library harboring a randomized 10nt PAM 5’ of target site 3. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160132

Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160135

Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#160133

Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#123361

CRISPR-Cpf1/Cas12a double knockout library. Targets 26 genes, chosen from analysis of human metastasis cohorts. It can be used to interrogate the genetic interactions driving metastasis.

Sidi Chen

Chow et al Nat Methods. 2019 May;16(5):405-408. doi

June 10, 2019

Academic Institutions and Nonprofits only

#209552

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

John Doench

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Dec. 5, 2023

Academic Institutions and Nonprofits only

#209551

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

John Doench

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Dec. 5, 2023

Academic Institutions and Nonprofits only

#164084

Knockout library targeting human genes required for mTORC1 activation and inhibition.

David Sabatini

Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

Jan. 11, 2021

Academic Institutions and Nonprofits only

#113585

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#113584

AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

Sidi Chen

Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

July 23, 2019

Academic Institutions and Nonprofits only

#234855

A CRISPRi library for inducible, genome-wide gene repression in Pseudomonas aeruginosa PA14.

Xue Liu

Zhang et al Nat Commun. 2025 Jul 1;16(1):5870. doi:

June 5, 2025

Academic Institutions and Nonprofits only

#85968

Barcode library for cloning gRNA sublibraries for single cell CRISPR analysis.

Jonathan Weissman

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Feb. 14, 2017

Academic Institutions and Nonprofits only

#132552

Knockout library targeting human SLC proteins.

Giulio Superti-Furga

Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

May 7, 2020

Academic Institutions and Nonprofits only

#174196

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Xiaole Shirley Liu

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Oct. 29, 2021

Academic Institutions and Nonprofits only

#174197

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Xiaole Shirley Liu

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Oct. 29, 2021

Academic Institutions and Nonprofits only

#229137

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

Thorsten Stiewe

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Feb. 24, 2025

Industry, Academic Institutions, and Nonprofits

#229138

Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

Thorsten Stiewe

Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

Feb. 24, 2025

Industry, Academic Institutions, and Nonprofits