We narrowed to 262 results for: crispr library

1. Human Transporter Knockout library

   Pooled Library

   #213695

   Purpose

   Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

2. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000096

   Purpose

   CRISPR gRNA knockout pooled library for targeting the mouse genome

   Depositor

   Eric Lander, David Sabatini

   Available Since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

3. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Eric Lander, David Sabatini

   Available Since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

4. Mouse Metabolism Library

   Pooled Library

   #163966

   Purpose

   Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

   Depositor

   Alec Kimmelman

   Article

   Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

   Use

   CRISPR and Lentiviral

   Available Since

   July 1, 2021

   Availability

   Academic Institutions and Nonprofits only

5. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

6. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

7. Mouse SLC KO Library

   Pooled Library

   #141436

   Purpose

   Expresses gRNAs for knockout of the mouse Solute Carrier family

   Depositor

   Giulio Superti-Furga

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   May 18, 2020

   Availability

   Academic Institutions and Nonprofits only

8. Human Paralog Knockout Library (pgPEN)

   Pooled Library

   #171172

   Purpose

   CRISPR library targets human duplicate paralog gene pairs

   Depositor

   Alice Berger

   Article

   Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

   Expression

   Mammalian

   Species

   Homo sapiens and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Sept. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

9. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75312

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

10. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

    Pooled Library

    #75313

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

11. lentiGuide-Puro-pKO-library

    Pooled Library

    #190744

    Purpose

    CRISPR/Cas9 paired-guide RNA library to delete proximal poly(A) sites in mouse melanoma.

    Depositor

    Robert Bradley

    Article

    Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR, Lentiviral, and Mouse Targeting

    Available Since

    Feb. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

12. psgRNA Library

    Pooled Library

    #115927

    Purpose

    Genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available Since

    June 6, 2019

    Availability

    Academic Institutions and Nonprofits only

13. Liu Lab MusCK Library A

    Pooled Library

    #174196

    Purpose

    MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

    Depositor

    Xiaole Shirley Liu

    Article

    Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

14. BARBEKO sgRNA library

    Pooled Library

    #174163

    Purpose

    iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

    Depositor

    Wensheng Wei

    Article

    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

    Pooled Library

    #104861

    Depositor

    Sarah Teichmann

    Article

    Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

    Available Since

    Sept. 9, 2019

    Availability

    Academic Institutions and Nonprofits only

16. Mouse messenger-RBP sgRNA library

    Pooled Library

    #169082

    Purpose

    CRISPR library targeting mouse genes

    Depositor

    Martin Turner

    Article

    Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

17. Green monkey (Chlorocebus sabaeus) sgRNA library

    Pooled Library

    #178284

    Purpose

    Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

    Depositor

    David Root, John Doench

    Article

    Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

    Expression

    Mammalian

    Species

    Chlorocebus sabaeus (african green monkey)

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

18. Liu Lab MusCK Library B

    Pooled Library

    #174197

    Purpose

    MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

    Depositor

    Xiaole Shirley Liu

    Article

    Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

19. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

20. DNA repair library with 1,573 sgRNAs

    Pooled Library

    #177663

    Purpose

    CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available Since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only