966 results

1. pAAV-CaMKIIa-hM4D(Gi)-mCherry (AAV1)

   Viral Prep

   #50477-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CaMKIIa-hM4D(Gi)-mCherry (#50477). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM4D(Gi)-mCherry plasmid DNA. CaMKIIa-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal silencing. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   CaMKII

   Tags

   mCherry

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

2. pENN.AAV.CB7.CI.mCherry.WPRE.RBG (AAV9)

   Viral Prep

   #105544-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pENN.AAV.CB7.CI.mCherry.WPRE.RBG (#105544). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.mCherry.WPRE.RBG plasmid DNA. CB7-driven mCherry. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   CB7

   Tags

   mCherry

   Available since

   Aug. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

3. AAV SYN PSAM4 GlyR IRES EGFP (AAV5)

   Viral Prep

   #119742-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from AAV SYN PSAM4 GlyR IRES EGFP (#119742). In addition to the viral particles, you will also receive purified AAV SYN PSAM4 GlyR IRES EGFP plasmid DNA. Synapsin-driven expression of PSAM4 GlyR IRES EGFP for neuronal silencing. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Scott Sternson

   Article

   Magnus et al Science. 2019 Mar 14. pii: science.aav52

   Promoter

   Syn

   Tags

   EGFP

   Available since

   Aug. 28, 2020

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-hSyn-GRAB_OT1.0 (AAV9)

   Viral Prep

   #185386-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSyn-GRAB_OT1.0 (#185386). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_OT1.0 plasmid DNA. hSyn-driven expression of the genetically-encoded fluorescent oxytocin(OT) sensor GRAB_OT1.0 in neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Yulong Li

   Article

   Qian et al Nat Biotechnol. 2023 Jan 2. doi: 10.1038

   Promoter

   Syn

   Tags

   None

   Available since

   June 26, 2024

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA (AAV1)

   Viral Prep

   #68719-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA (#68719). In addition to the viral particles, you will also receive purified pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA plasmid DNA. CAG-driven, Cre-dependent GCaMP6f calcium sensor with bicistronic mRuby2. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Mark Huebener, Tobias Bonhoeffer, Tobias Rose

   Article

   Rose et al Science. 2016 Jun 10;352(6291):1319-22.

   Promoter

   CAG-FLEX

   Tags

   mRuby2 (Cre-dependent)

   Available since

   June 5, 2018

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-hDlx-Flex-dTomato-Fishell_7 (AAV9)

   Viral Prep

   #83894-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hDlx-Flex-dTomato-Fishell_7 (#83894). In addition to the viral particles, you will also receive purified pAAV-hDlx-Flex-dTomato-Fishell_7 plasmid DNA. hDlx-driven, Cre-dependent expression of dTomato. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   hDlx

   Tags

   dTomato (Cre-dependent)

   Available since

   Nov. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 (AAV9)

   Viral Prep

   #124650-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 (#124650). In addition to the viral particles, you will also receive purified pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 plasmid DNA. CamKIIa-driven expression of C1V1(t/t) fused to mScarlet fluorophore and targeted to neuronal soma for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Christopher Harvey

   Article

   Chettih et al Nature. 2019 Mar 6. pii: 10.1038/s41586-

   Promoter

   CaMKII

   Tags

   mScarlet

   Available since

   Dec. 2, 2019

   Availability

   Academic Institutions and Nonprofits only

8. pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 (AAV9)

   Viral Prep

   #100839-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 (#100839). In addition to the viral particles, you will also receive purified pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 plasmid DNA. CAG-driven, Cre-dependent GCaMP6m calcium sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project, Douglas Kim

   Article

   Chen et al Nature. 2013 Jul 18;499(7458):295-300. d

   Promoter

   CAG

   Tags

   None

   Available since

   May 14, 2018

   Availability

   Academic Institutions and Nonprofits only

9. AAV-hSyn-Ribo-jGCaMP8s (AAV1)

   Viral Prep

   #167572-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from AAV-hSyn-Ribo-jGCaMP8s (#167572). In addition to the viral particles, you will also receive purified AAV-hSyn-Ribo-jGCaMP8s plasmid DNA. Synapsin-driven neuronal expression of soma-targeted (RL-10, ribosomal tag) jGCaMP8s. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Marianne Fyhn

   Article

   Grodem et al Nat Commun. 2023 Feb 4;14(1):608. doi: 1

   Promoter

   Syn

   Tags

   None

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-hSynapsin1-axon-jGCaMP8s-P2A-mRuby3 (AAV1)

    Viral Prep

    #172921-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSynapsin1-axon-jGCaMP8s-P2A-mRuby3 (#172921). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-jGCaMP8s-P2A-mRuby3 plasmid DNA. hSyn-driven expression of calcium sensor jGCaMP8s in axons with cytosolic expression of mRuby3. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Promoter

    Syn

    Tags

    mRuby3

    Available since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

11. pACAGW-ChR2-Venus-AAV (AAV1)

    Viral Prep

    #20071-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pACAGW-ChR2-Venus-AAV (#20071). In addition to the viral particles, you will also receive purified pACAGW-ChR2-Venus-AAV plasmid DNA. CAG-driven, channelrhodopsin fused to Venus for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karel Svoboda

    Article

    Leopoldo et al Nature. 2009 Jan 18.

    Promoter

    CAGG

    Tags

    Venus

    Available since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

12. pAAV_BiVIPe4_ChR2_mCherry (AAV PHP.eB)

    Viral Prep

    #213856-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiVIPe4_ChR2_mCherry (#213856). In addition to the viral particles, you will also receive purified pAAV_BiVIPe4_ChR2_mCherry plasmid DNA. Expression of mCherry-tagged channelrhodopsin-2 under the control of the VIP interneuron-targeting enhancer E4. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    mCherry

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-CaMKIIa-hM3D(Gq)-mCherry (AAV2)

    Viral Prep

    #50476-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-CaMKIIa-hM3D(Gq)-mCherry (#50476). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM3D(Gq)-mCherry plasmid DNA. CaMKIIa-driven hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    CaMKII

    Tags

    mCherry

    Available since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

14. pENN.AAV.EF1a.eGFP.WPRE.rBG (AAV1)

    Viral Prep

    #105547-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pENN.AAV.EF1a.eGFP.WPRE.rBG (#105547). In addition to the viral particles, you will also receive purified pENN.AAV.EF1a.eGFP.WPRE.rBG plasmid DNA. EF1a-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    EF1a

    Tags

    EGFP

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pAAV_hSyn1-SIO-stGtACR2-FusionRed (AAV Retrograde)

    Viral Prep

    #105677-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV_hSyn1-SIO-stGtACR2-FusionRed (#105677). In addition to the viral particles, you will also receive purified pAAV_hSyn1-SIO-stGtACR2-FusionRed plasmid DNA. Synapsin-driven, Cre-dependent, soma-targeted anion-conducting channelrhodopsin fused to FusionRed for optogenetic inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Nat Commun. 2018 Oct 8;9(1):4125. doi: 1

    Promoter

    Syn

    Tags

    FusionRed (Cre-dependent)

    Available since

    July 8, 2020

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-Ef1a-Con/Fon-GCaMP6F (AAV8)

    Viral Prep

    #137122-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Fon-GCaMP6F (#137122). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Fon-GCaMP6F plasmid DNA. EF1a-driven, Cre and Flp-dependent expression of GCaMP6f. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    None

    Available since

    March 12, 2021

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-nEF-Con/Fon-iC++-EYFP (AAV8)

    Viral Prep

    #137155-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-iC++-EYFP (#137155). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-iC++-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of chloride-conducting channelrhodopsin iC++-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre and Flp-dependent)

    Available since

    Dec. 1, 2020

    Availability

    Academic Institutions and Nonprofits only

18. AAV-CAG-jGCaMP8f-WPRE (AAV Retrograde)

    Viral Prep

    #179254-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CAG-jGCaMP8f-WPRE (#179254). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8f-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8f. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CAG

    Tags

    None

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

19. AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035) (AAV PHP.eB)

    Viral Prep

    #214853-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035) (#214853). In addition to the viral particles, you will also receive purified AiP14035: pAAV-AiE0452h_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4035) plasmid DNA. minBG-driven expression of CoChR-EGFP striatal indirect pathway medium spiny neurons (D2 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Promoter

    Tags

    EGFP

    Available since

    Nov. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

20. pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (AAV Retrograde)

    Viral Prep

    #104492-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-FLEX-jGCaMP7f-WPRE (#104492). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7f-WPRE plasmid DNA. Syn-driven, Cre-dependent GCaMP7f calcium sensor. These AAV preparations are suitable purity for injection into animals. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    June 14, 2018

    Availability

    Academic Institutions and Nonprofits only

21. pAAV_BiPVe4_ChR2_mCherry (AAV PHP.eB)

    Viral Prep

    #213937-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiPVe4_ChR2_mCherry (#213937). In addition to the viral particles, you will also receive purified pAAV_BiPVe4_ChR2_mCherry plasmid DNA. Expression of mCherry-tagged channelrhodopsin-2 under the control of the chandelier cell-targeting enhancer E4. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    mCherry

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

22. pAAV_BiPVe4_dTomato_nlsdTomato (AAV PHP.eB)

    Viral Prep

    #213936-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiPVe4_dTomato_nlsdTomato (#213936). In addition to the viral particles, you will also receive purified pAAV_BiPVe4_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the chandelier cell-targeting enhancer E4. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    dTomato

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

23. pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry (PV2670) (AAV9)

    Viral Prep

    #100061-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry (PV2670) (#100061). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO C1V1 (t/t)-TS-mCherry (PV2670) plasmid DNA. EFIa-driven, Cre-dependent, C1V1 (t/t) fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    mCherry (Cre-dependent)

    Available since

    April 6, 2018

    Availability

    Academic Institutions and Nonprofits only

24. pAAV-hSyn-dLight1.2 (AAV1)

    Viral Prep

    #111068-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn-dLight1.2 (#111068). In addition to the viral particles, you will also receive purified pAAV-hSyn-dLight1.2 plasmid DNA. Synapsin-driven expression of dLight1.2 dopamine sensor. This sensor has a slightly increased dynamic range and is better for 2P imaging in vivo. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Patriarchi et al Science. 2018 Jun 29;360(6396). pii: sci

    Promoter

    Tags

    None

    Available since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

25. AAV-CamKIIa-jGCaMP8m-WPRE (AAV5)

    Viral Prep

    #176751-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from AAV-CamKIIa-jGCaMP8m-WPRE (#176751). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8m-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CamKIIalpha

    Tags

    None

    Available since

    Jan. 25, 2024

    Availability

    Academic Institutions and Nonprofits only

26. pAAV-hsyn-GRAB_rDA-mut (AAV9)

    Viral Prep

    #140558-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hsyn-GRAB_rDA-mut (#140558). In addition to the viral particles, you will also receive purified pAAV-hsyn-GRAB_rDA-mut plasmid DNA. Synapsin-driven expression of control red fluorescent dopamine sensor GRAB_rDA-mut (does not respond to DA). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Sun et al Nat Methods. 2020 Nov;17(11):1156-1166.

    Promoter

    Syn

    Tags

    None

    Available since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

27. pAAV-CAG-GFP (AAV CAP-B10)

    Viral Prep

    #37825-CAP-B10

    Purpose

    Ready-to-use AAV CAP-B10 particles produced from pAAV-CAG-GFP (#37825). In addition to the viral particles, you will also receive purified pAAV-CAG-GFP plasmid DNA. CAG-driven GFP expression. These AAV were produced with the CAP-B10 serotype, which permits efficient transduction of both inhibitory and excitatory neurons in the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Promoter

    CAG

    Tags

    GFP

    Available since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

28. pAAV-FLEX-tdTomato (AAV8)

    Viral Prep

    #28306-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-FLEX-tdTomato (#28306). In addition to the viral particles, you will also receive purified pAAV-FLEX-tdTomato plasmid DNA. CAG-driven, Cre-dependent tdTomato expression control. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Promoter

    CAG

    Tags

    tdTomato (Cre-dependent)

    Available since

    Oct. 18, 2021

    Availability

    Academic Institutions and Nonprofits only

29. pAAV-Ef1a-fDIO mCherry (AAV2)

    Viral Prep

    #114471-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-Ef1a-fDIO mCherry (#114471). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO mCherry plasmid DNA. Ef1a-driven, Flp recombinase-dependent expression of mCherry. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    mCherry (Flp-dependent)

    Available since

    March 31, 2020

    Availability

    Academic Institutions and Nonprofits only

30. pAAV-hSyn Con/Fon EYFP (AAV Retrograde)

    Viral Prep

    #55650-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn Con/Fon EYFP (#55650). In addition to the viral particles, you will also receive purified pAAV-hSyn Con/Fon EYFP plasmid DNA. Synapsin driven, Cre and Flp-dependent EYFP expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    Syn

    Tags

    EYFP (Cre- and Flp-dependent)

    Available since

    Sept. 8, 2020

    Availability

    Academic Institutions and Nonprofits only

31. AAV-FLEX-Arch-GFP (AAV1)

    Viral Prep

    #22222-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-FLEX-Arch-GFP (#22222). In addition to the viral particles, you will also receive purified AAV-FLEX-Arch-GFP plasmid DNA. CAG-driven cre-dependent Arch-GFP expression for optogenetic neural inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Chow et al Nature. 2010 Jan 7. 463(7277):98-102.

    Promoter

    CAG

    Tags

    GFP (Cre-dependent)

    Available since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

32. pAAV-S5E2-ChR2-mCherry (AAV1)

    Viral Prep

    #135634-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-S5E2-ChR2-mCherry (#135634). In addition to the viral particles, you will also receive purified pAAV-S5E2-ChR2-mCherry plasmid DNA. Expression of ChR2-mCherry under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    mCherry

    Available since

    Nov. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

33. AAV-mDlx-jGCaMP8s-WPRE (AAV1)

    Viral Prep

    #176755-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-mDlx-jGCaMP8s-WPRE (#176755). In addition to the viral particles, you will also receive purified AAV-mDlx-jGCaMP8s-WPRE plasmid DNA. mDlx-driven expression of the calcium sensor jGCaMP8s in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    mDlx

    Tags

    None

    Available since

    Sept. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

34. AAV-EF1a-jGCaMP8m-WPRE (AAV9)

    Viral Prep

    #176757-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from AAV-EF1a-jGCaMP8m-WPRE (#176757). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8m-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    EF1a

    Tags

    None

    Available since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

35. pAAV-mDlx-NLS-mRuby2 (AAV Retrograde)

    Viral Prep

    #99130-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    mDLX5/6

    Tags

    mRuby2

    Available since

    Sept. 18, 2019

    Availability

    Academic Institutions and Nonprofits only

36. pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP (AAV8)

    Viral Prep

    #137148-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP (#137148). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of Arch3.3-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre and Flp-dependent)

    Available since

    May 6, 2021

    Availability

    Academic Institutions and Nonprofits only

37. pAAV-hDlx-Flex-dTomato-Fishell_7 (AAV Retrograde)

    Viral Prep

    #83894-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hDlx-Flex-dTomato-Fishell_7 (#83894). In addition to the viral particles, you will also receive purified pAAV-hDlx-Flex-dTomato-Fishell_7 plasmid DNA. hDlx-driven, Cre-dependent expression of dTomato. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

    Promoter

    hDlx

    Tags

    dTomato (Cre-dependent)

    Available since

    June 22, 2020

    Availability

    Academic Institutions and Nonprofits only

38. AAV-hSyn1-GCaMP6s-P2A-nls-dTomato (AAV1)

    Viral Prep

    #51084-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-hSyn1-GCaMP6s-P2A-nls-dTomato (#51084). In addition to the viral particles, you will also receive purified AAV-hSyn1-GCaMP6s-P2A-nls-dTomato plasmid DNA. GCaMP6s calcium sensor and bicistronic, physically separate nuclear localized dTomato expression under a human synapsin1 promoter. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting

    Promoter

    Syn

    Tags

    nuclear dTomato (physically separate, not a fusion protein)

    Available since

    Aug. 24, 2017

    Availability

    Academic Institutions and Nonprofits only

39. pGP-AAV-syn-FLEX-jGCaMP7s-WPRE (AAV Retrograde)

    Viral Prep

    #104491-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-syn-FLEX-jGCaMP7s-WPRE (#104491). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7s-WPRE plasmid DNA. Synapsin-driven, Cre-dependent, GCaMP7s calcium sensor. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project, Douglas Kim

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    June 14, 2018

    Availability

    Academic Institutions and Nonprofits only

40. pAAV-CAG-NIR-GECO2G (AAV2)

    Viral Prep

    #159605-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-CAG-NIR-GECO2G (#159605). In addition to the viral particles, you will also receive purified pAAV-CAG-NIR-GECO2G plasmid DNA. CAG-driven expression of the near-infrared calcium indicator NIR-GECO2G. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Robert Campbell

    Article

    Qian et al PLoS Biol. 2020 Nov 24;18(11):e3000965.

    Promoter

    CAG

    Tags

    None

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

41. pAAV_hsyn_NES-his-CaMPARI2-F391W-WPRE-SV40 (AAV1)

    Viral Prep

    #101061-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV_hsyn_NES-his-CaMPARI2-F391W-WPRE-SV40 (#101061). In addition to the viral particles, you will also receive purified pAAV_hsyn_NES-his-CaMPARI2-F391W-WPRE-SV40 plasmid DNA. Synapsin-driven, photoconvertible (irreversible green-to-red) calcium integrator his-tagged CaMPARI2-F391W. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Moeyaert et al Nat Commun. 2018 Oct 25;9(1):4440. doi:

    Promoter

    Syn

    Tags

    None

    Available since

    July 23, 2018

    Availability

    Academic Institutions and Nonprofits only

42. pAAV_BiCHATe27_dTomato_nlsdTomato (AAV PHP.eB)

    Viral Prep

    #213829-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiCHATe27_dTomato_nlsdTomato (#213829). In addition to the viral particles, you will also receive purified pAAV_BiCHATe27_dTomato_nlsdTomato plasmid DNA. Bicistronic expression of dTomato and nuclear-targeted dTomato under the control of the cholinergic neuron-targeting enhancer E27. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    dTomato

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

43. pAAV-S5E2-GFP-fGFP (AAV PHP.eB)

    Viral Prep

    #135631-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-GFP-fGFP (#135631). In addition to the viral particles, you will also receive purified pAAV-S5E2-GFP-fGFP plasmid DNA. Bicistronic expression of GFP and membrane-targeted GFP under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    EGFP

    Available since

    Nov. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

44. AAV-EF1a-jGCaMP8s-WPRE (AAV1)

    Viral Prep

    #176758-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-EF1a-jGCaMP8s-WPRE (#176758). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8s-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8s (more sensitive). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    EF1a

    Tags

    None

    Available since

    July 12, 2023

    Availability

    Academic Institutions and Nonprofits only

45. pAAV-nEF-Coff/Fon-iC++-EYFP (AAV8)

    Viral Prep

    #137157-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Coff/Fon-iC++-EYFP (#137157). In addition to the viral particles, you will also receive purified pAAV-nEF-Coff/Fon-iC++-EYFP plasmid DNA. nEF-driven, Flp-dependent expression of chloride-conducting channelrhodopsin iC++-EYFP (inhibited in presence of Cre) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Flp-dependent)

    Available since

    Feb. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

46. pAAV-CAG-iSeroSnFR-Nlgn (AAV9)

    Viral Prep

    #128485-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CAG-iSeroSnFR-Nlgn (#128485). In addition to the viral particles, you will also receive purified pAAV-CAG-iSeroSnFR-Nlgn plasmid DNA. CAG-driven expression of a fluorescent reporter for serotonin (localized to dendrites). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Unger et al Cell. 2020 Dec 12. pii: S0092-8674(20)31

    Promoter

    CAG

    Tags

    None

    Available since

    Feb. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

47. AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) (AAV PHP.eB)

    Viral Prep

    #214852-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) (#214852). In addition to the viral particles, you will also receive purified AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) plasmid DNA. minBG-driven expression of CoChR-EGFP in striatal direct pathway medium spiny neurons (D1 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Promoter

    Tags

    EGFP

    Available since

    Nov. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

48. pAAV.GFA104.PI.eGFP.WPRE.bGH (AAV5)

    Viral Prep

    #100896-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.GFA104.PI.eGFP.WPRE.bGH (#100896). In addition to the viral particles, you will also receive purified pAAV.GFA104.PI.eGFP.WPRE.bGH plasmid DNA. GFA104-driven eGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Philip Haydon

    Article

    Ortinski et al Nat Neurosci. 2010 May;13(5):584-91. doi

    Promoter

    GFA104 (GFAP promoter)

    Tags

    EGFP

    Available since

    April 6, 2018

    Availability

    Academic Institutions and Nonprofits only

49. pAAV-S5E2-ChR2-mCherry (AAV9)

    Viral Prep

    #135634-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-ChR2-mCherry (#135634). In addition to the viral particles, you will also receive purified pAAV-S5E2-ChR2-mCherry plasmid DNA. Expression of ChR2-mCherry under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    mCherry

    Available since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

50. pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (AAV Retrograde)

    Viral Prep

    #125712-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE (#125712). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa(0.4)-eOPN3-mScarlet-WPRE plasmid DNA. CaMKIIa-driven expression of the optimized mosquito OPN3 rhodopsin in-frame with mScarlet. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Neuron. 2021 May 10. pii: S0896-6273(21)

    Promoter

    short version of αCamKinase II promoter (0.4kb)

    Tags

    None

    Available since

    Jan. 8, 2025

    Availability

    Academic Institutions and Nonprofits only