966 results

1. pTR-UF11 (AAV.A01.T)

   Viral Prep

   #157970-AAV.A01.T

   Purpose

   Ready-to-use AAV2 in TMN200 particles produced from pTR-UF11 (#157970). In addition to the viral particles, you will also receive purified pTR-UF11 plasmid DNA. 'Humanized' GFP driven by Chimeric CMV/Chicken Beta Actin promoter

   Depositor

   Sergei Zolotukhin

   Article

   Burger et al Mol Ther. 2004 Aug;10(2):302-17. doi: 10

   Promoter

   chimeric CMV/Chicken Beta actin (CBA)

   Tags

   GFP

   Available since

   Dec. 21, 2020

   Availability

   Academic Institutions and Nonprofits only

2. pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (AAV1)

   Viral Prep

   #106183-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (#106183). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S plasmid DNA. Synapsin-driven, Cre-dependent SF-Venus-iGluSnFR.A184S glutamate sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

   Promoter

   Syn

   Tags

   Venus (Cre-dependent)

   Available since

   Dec. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-S5E2-Gq-P2A-dTomato (AAV1)

   Viral Prep

   #135635-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Promoter

   Tags

   dTomato (physically separate, not a fusion protein)

   Available since

   Nov. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

4. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV8)

   Viral Prep

   #87306-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Li Zhang

   Article

   Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

   Promoter

   EF1a

   Tags

   None

   Available since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-hDlx-Flex-GFP-Fishell_6 (AAV Retrograde)

   Viral Prep

   #83895-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-hDlx-Flex-GFP-Fishell_6 (#83895). In addition to the viral particles, you will also receive purified pAAV-hDlx-Flex-GFP-Fishell_6 plasmid DNA. mDlx-driven, Cre-dependent expression of GFP. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   hDlx

   Tags

   GFP

   Available since

   March 2, 2020

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-Ef1a-mCherry (AAV9)

   Viral Prep

   #114470-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   EF1a

   Tags

   mCherry

   Available since

   Jan. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-Ef1a-mCherry (AAV2)

   Viral Prep

   #114470-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   EF1a

   Tags

   mCherry

   Available since

   Nov. 29, 2021

   Availability

   Academic Institutions and Nonprofits only

8. pACAGW-ChR2-Venus-AAV (AAV9)

   Viral Prep

   #20071-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pACAGW-ChR2-Venus-AAV (#20071). In addition to the viral particles, you will also receive purified pACAGW-ChR2-Venus-AAV plasmid DNA. CAG-driven, channelrhodopsin fused to Venus for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karel Svoboda

   Article

   Leopoldo et al Nature. 2009 Jan 18.

   Promoter

   CAGG

   Tags

   Venus

   Available since

   March 15, 2018

   Availability

   Academic Institutions and Nonprofits only

9. pAAV-CAG-eYFP (AAV2)

   Viral Prep

   #104055-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV-CAG-eYFP (#104055). In addition to the viral particles, you will also receive purified pAAV-CAG-eYFP plasmid DNA. CAG-driven eYFP expression control. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Viviana Gradinaru

   Article

   Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

   Promoter

   CAG

   Tags

   EYFP

   Available since

   June 13, 2023

   Availability

   Academic Institutions and Nonprofits only

10. pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH (AAV9)

    Viral Prep

    #100049-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH (#100049). In addition to the viral particles, you will also receive purified pAAV.hSynap.ChETA(E123T/H134R)-eYFP.WPRE.hGH plasmid DNA. Synapsin-driven ChETA(E123T/H134R)-EYFP expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    Syn

    Tags

    EYFP

    Available since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

11. pGP-AAV-syn-FLEX-jGCaMP7c variant 1513-WPRE (AAV1)

    Viral Prep

    #105322-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-FLEX-jGCaMP7c variant 1513-WPRE (#105322). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP7c variant 1513-WPRE plasmid DNA. Synapsin-driven, Cre-dependent jGCaMP7c expression. jGCaMP7c exhibits high contrast between peak fluorescence and resting fluorescence. It is useful for activity imaging of large populations of densely-labeled neurons because background fluorescence from inactive neurons is reduced. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    Syn

    Tags

    None

    Available since

    June 13, 2019

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-nEF-Con/Foff 2.0-ChR2-mCherry (AAV8)

    Viral Prep

    #137143-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-ChR2-mCherry (#137143). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-ChR2-mCherry plasmid DNA. nEF-driven, Cre-dependent expression of ChR2-mCherry for optogenetic activation (inhibited in the presence of Flp recombinase). These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    mCherry (Cre-dependent)

    Available since

    Feb. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

13. pAAV.GFAP.SF-iGluSnFR.A184S (AAV1)

    Viral Prep

    #106192-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.GFAP.SF-iGluSnFR.A184S (#106192). In addition to the viral particles, you will also receive purified pAAV.GFAP.SF-iGluSnFR.A184S plasmid DNA. GFAP-driven expression of SF-iGluSnFR.A184S. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    GFAP

    Tags

    None

    Available since

    Sept. 11, 2020

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-CAG-eYFP (AAV PHP.eB)

    Viral Prep

    #104055-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-CAG-eYFP (#104055). In addition to the viral particles, you will also receive purified pAAV-CAG-eYFP plasmid DNA. CAG-driven eYFP expression control. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

    Promoter

    CAG

    Tags

    EYFP

    Available since

    June 13, 2023

    Availability

    Academic Institutions and Nonprofits only

15. AAV-hSyn-Ribo-jGCaMP8m (AAV1)

    Viral Prep

    #167574-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-hSyn-Ribo-jGCaMP8m (#167574). In addition to the viral particles, you will also receive purified AAV-hSyn-Ribo-jGCaMP8m plasmid DNA. Synapsin-driven neuronal expression of soma-targeted (RL-10, ribosomal tag) jGCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Marianne Fyhn

    Article

    Grodem et al Nat Commun. 2023 Feb 4;14(1):608. doi: 1

    Promoter

    Syn

    Tags

    None

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

16. pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (AAV PHP.eB)

    Viral Prep

    #104496-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE (#104496). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7f-WPRE plasmid DNA. CAG-driven, Cre-dependent jGCaMP7f calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    CAG

    Tags

    None

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

17. pZac2.1-GfaABC1D-lck-jGCaMP8m (AAV1)

    Viral Prep

    #176760-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pZac2.1-GfaABC1D-lck-jGCaMP8m (#176760). In addition to the viral particles, you will also receive purified pZac2.1-GfaABC1D-lck-jGCaMP8m plasmid DNA. GfaABC1D-driven expression of membrane-bound calcium sensor GCaMP8m. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    GfaABC1D

    Tags

    None

    Available since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

18. pAAV.hSyn1.Twitch2B.WPRE.SV40 (AAV1)

    Viral Prep

    #100040-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSyn1.Twitch2B.WPRE.SV40 (#100040). In addition to the viral particles, you will also receive purified pAAV.hSyn1.Twitch2B.WPRE.SV40 plasmid DNA. Synapsin-driven expression of (FRET)-based calcium biosensor Twitch2B. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Oliver Griesbeck

    Article

    Thestrup et al Nat Methods. 2014 Jan 5. doi: 10.1038/nm

    Promoter

    Syn

    Tags

    None

    Available since

    March 8, 2018

    Availability

    Academic Institutions and Nonprofits only

19. pAAV.hSyn.iGluSnFr.WPRE.SV40 (AAV5)

    Viral Prep

    #98929-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.hSyn.iGluSnFr.WPRE.SV40 (#98929). In addition to the viral particles, you will also receive purified pAAV.hSyn.iGluSnFr.WPRE.SV40 plasmid DNA. Synapsin-driven, iGluSnFr glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    Syn

    Tags

    None

    Available since

    Feb. 27, 2018

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-Ef1a-mCherry (AAV1)

    Viral Prep

    #114470-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-mCherry (#114470). In addition to the viral particles, you will also receive purified pAAV-Ef1a-mCherry plasmid DNA. EF1a-driven mCherry expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Promoter

    EF1a

    Tags

    mCherry

    Available since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

21. pAAV-mDlx-ChR2-mCherry-Fishell-3 (AAV Retrograde)

    Viral Prep

    #83898-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-mDlx-ChR2-mCherry-Fishell-3 (#83898). In addition to the viral particles, you will also receive purified pAAV-mDlx-ChR2-mCherry-Fishell-3 plasmid DNA. mDlx-driven expression of ChR2 fused to mCherry. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

    Promoter

    mDlx

    Tags

    mCherry

    Available since

    March 2, 2020

    Availability

    Academic Institutions and Nonprofits only

22. pGP-AAV-CAG-FLEX-jGCaMP8s-WPRE (AAV Retrograde)

    Viral Prep

    #162380-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pGP-AAV-CAG-FLEX-jGCaMP8s-WPRE (#162380). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8s-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of calcium sensor GCaMP8s (more sensitive). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    CAG

    Tags

    None

    Available since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only

23. pAAV.hSyn.iGluSnFr.WPRE.SV40 (AAV1)

    Viral Prep

    #98929-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSyn.iGluSnFr.WPRE.SV40 (#98929). In addition to the viral particles, you will also receive purified pAAV.hSyn.iGluSnFr.WPRE.SV40 plasmid DNA. Synapsin-driven, iGluSnFr glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    Syn

    Tags

    None

    Available since

    Feb. 27, 2018

    Availability

    Academic Institutions and Nonprofits only

24. pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) (AAV2)

    Viral Prep

    #121538-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) (#121538). In addition to the viral particles, you will also receive purified pOTTC1484 - pAAV SYN1 HA-hM4D(Gi) plasmid DNA. Synapsin-driven, HA-tagged hM4D(Gi) for neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Christopher Richie

    Article

    Galvan et al Eur J Neurosci. 2019 May 7. doi: 10.1111

    Promoter

    Syn

    Tags

    HA

    Available since

    Sept. 25, 2019

    Availability

    Academic Institutions and Nonprofits only

25. pAAV_BiLAMP5e3_ChR2_mCherry (AAV PHP.eB)

    Viral Prep

    #213915-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV_BiLAMP5e3_ChR2_mCherry (#213915). In addition to the viral particles, you will also receive purified pAAV_BiLAMP5e3_ChR2_mCherry plasmid DNA. Expression of mCherry-tagged channelrhodopsin-2 under the control of the Lamp5 interneuron-targeting enhancer E3. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Furlanis et al Neuron. 2025 May 21;113(10):1525-1547.e1

    Promoter

    Tags

    mCherry

    Available since

    Dec. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

26. pAAV-S5E2-C1V1-eYFP (AAV PHP.eB)

    Viral Prep

    #135633-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-C1V1-eYFP (#135633). In addition to the viral particles, you will also receive purified pAAV-S5E2-C1V1-eYFP plasmid DNA. Expression of red-shifted opsin C1V1 fused to EYFP under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    EYFP

    Available since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

27. pAAV-hSyn-GRAB_DA1h (AAV Retrograde)

    Viral Prep

    #113050-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-GRAB_DA1h (#113050). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_DA1h plasmid DNA. Synapsin-driven expression of GRAB-DA1h dopamine sensor in neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

    Promoter

    Syn

    Tags

    None

    Available since

    Nov. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

28. pAAV-mDlx-NLS-mRuby2 (AAV2)

    Viral Prep

    #99130-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    mDLX5/6

    Tags

    mRuby2

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

29. AAV-mDlx-jGCaMP8s-WPRE (AAV9)

    Viral Prep

    #176755-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from AAV-mDlx-jGCaMP8s-WPRE (#176755). In addition to the viral particles, you will also receive purified AAV-mDlx-jGCaMP8s-WPRE plasmid DNA. mDlx-driven expression of the calcium sensor jGCaMP8s in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    mDlx

    Tags

    None

    Available since

    Feb. 5, 2024

    Availability

    Academic Institutions and Nonprofits only

30. pSMAL-CellTag-V2 (Concentrated Lentiviral Prep)

    Viral Prep

    #115644-LVC

    Purpose

    Ready-to-use Concentrated Lentiviral Prep particles produced from pSMAL-CellTag-V2 (#115644). In addition to the viral particles, you will also receive purified pSMAL-CellTag-V2 plasmid DNA. Ready-to-use lentiviral particles carrying version 2 of the CellTag barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics.

    Depositor

    Samantha Morris

    Article

    Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

    Promoter

    Minimal CMV

    Tags

    EGFP

    Available since

    Oct. 29, 2019

    Availability

    Academic Institutions and Nonprofits only

31. pENN.AAV.EF1a.eGFP.WPRE.rBG (AAV8)

    Viral Prep

    #105547-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pENN.AAV.EF1a.eGFP.WPRE.rBG (#105547). In addition to the viral particles, you will also receive purified pENN.AAV.EF1a.eGFP.WPRE.rBG plasmid DNA. EF1a-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    EF1a

    Tags

    EGFP

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

32. pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (AAV1)

    Viral Prep

    #68720-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (#68720). In addition to the viral particles, you will also receive purified pAAV-hSyn1-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA plasmid DNA. Cre-dependent GCaMP6s calcium sensor and bicistronic, physically separate mRuby2 expression under a human synapsin1 promoter. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Mark Huebener, Tobias Rose, Tobias Bonhoeffer

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Promoter

    hSyn1-FLEX

    Tags

    mRuby2 (Cre-dependent)

    Available since

    March 7, 2018

    Availability

    Academic Institutions and Nonprofits only

33. pAAV-CaMKIIa-hChR2(E123A)-EYFP (AAV9)

    Viral Prep

    #35505-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-EYFP (#35505). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-EYFP plasmid DNA. CaMKIIa-driven hChR2(E123A)-EYFP expression for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    CaMKII

    Tags

    EYFP

    Available since

    May 24, 2018

    Availability

    Academic Institutions and Nonprofits only

34. pAAV.hSynapsin.SF-iGluSnFR.S72A (AAV1)

    Viral Prep

    #106176-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSynapsin.SF-iGluSnFR.S72A (#106176). In addition to the viral particles, you will also receive purified pAAV.hSynapsin.SF-iGluSnFR.S72A plasmid DNA. hSynapsin driven SF-iGluSnFR.S72A, glutamate sensor. The S72A mutant has lower affinity for glutamate. Slower on-rate and faster off-rate. Enhanced temporal resolution and spatial resolution. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Tags

    None

    Available since

    Feb. 25, 2019

    Availability

    Academic Institutions and Nonprofits only

35. pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP (AAV8)

    Viral Prep

    #137139-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP (#137139). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-ChR2(ET/TC)-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of ChR2(E123T/T159C)-EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre and Flp-dependent)

    Available since

    May 19, 2021

    Availability

    Academic Institutions and Nonprofits only

36. pAAV.CAG.iAChSnFR (AAV9)

    Viral Prep

    #137955-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.CAG.iAChSnFR (#137955). In addition to the viral particles, you will also receive purified pAAV.CAG.iAChSnFR plasmid DNA. CAG-driven iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Borden et al bioRxiv 2020

    Promoter

    CAG

    Tags

    None

    Available since

    Nov. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

37. pGP-AAV-GFAP-iGABASnFR2-WPRE (AAV1)

    Viral Prep

    #218871-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-GFAP-iGABASnFR2-WPRE (#218871). In addition to the viral particles, you will also receive purified pGP-AAV-GFAP-iGABASnFR2-WPRE plasmid DNA. GFAP-driven expression of the improved GABA sensor iGABASnFR2 (positive change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    GFAP

    Tags

    None

    Available since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

38. pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (AAV PHP.eB)

    Viral Prep

    #104495-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE (#104495). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP7s-WPRE plasmid DNA. CAG-driven, Cre-dependent GCaMP7s calcium sensor. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Douglas Kim, GENIE Project

    Article

    Dana et al Nat Methods. 2019 Jul;16(7):649-657. doi

    Promoter

    CAG

    Tags

    None

    Available since

    Feb. 5, 2024

    Availability

    Academic Institutions and Nonprofits only

39. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A (Lentiviral Prep)

    Viral Prep

    #92385-LV

    Purpose

    Ready-to-use Lentiviral Prep particles produced from Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A (#92385). In addition to the viral particles, you will also receive purified Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A plasmid DNA.

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Promoter

    Tags

    None

    Available since

    Sept. 2, 2020

    Availability

    Academic Institutions and Nonprofits only

40. pAAV-Ef1a-fDIO EYFP (AAV2)

    Viral Prep

    #55641-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-Ef1a-fDIO EYFP (#55641). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO EYFP plasmid DNA. EF1a-driven, Flp-dependent expression of EYFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    EF1a

    Tags

    EYFP (Flp-dependent)

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

41. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV5)

    Viral Prep

    #87306-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Li Zhang

    Article

    Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

    Promoter

    EF1a

    Tags

    None

    Available since

    July 22, 2020

    Availability

    Academic Institutions and Nonprofits only

42. pAAV-EF1a-vCre (AAV Retrograde)

    Viral Prep

    #55638-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-EF1a-vCre (#55638). In addition to the viral particles, you will also receive purified pAAV-EF1a-vCre plasmid DNA. EF1a-driven expression of VCre. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    EF1a

    Tags

    None

    Available since

    Nov. 12, 2020

    Availability

    Academic Institutions and Nonprofits only

43. pAAV-CAG-DIO-EYFP (AAV PHP.V1)

    Viral Prep

    #104052-AAVPHP.V1

    Purpose

    Ready-to-use AAV PHP.V1 particles produced from pAAV-CAG-DIO-EYFP (#104052). In addition to the viral particles, you will also receive purified pAAV-CAG-DIO-EYFP plasmid DNA. CAG-driven, Cre-dependent expression of EYFP. These AAV were produced with the PHP.V1 serotype, which permits efficient transduction of brain vascular cells. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

    Promoter

    CAG

    Tags

    EYFP (Cre-dependent)

    Available since

    July 24, 2020

    Availability

    Academic Institutions and Nonprofits only

44. pAAV.hSyn.CaMPARI.WPRE.SV40 (AAV9)

    Viral Prep

    #100832-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.hSyn.CaMPARI.WPRE.SV40 (#100832). In addition to the viral particles, you will also receive purified pAAV.hSyn.CaMPARI.WPRE.SV40 plasmid DNA. Synapsin-driven, photoconvertible (irreversible green-to-red) calcium integrator. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger, Eric Schreiter

    Article

    Fosque et al Science. 2015 Feb 13;347(6223):755-60. d

    Promoter

    Syn

    Tags

    None

    Available since

    April 17, 2018

    Availability

    Academic Institutions and Nonprofits only

45. pAAV-nEF-NpHR3.3-EYFP (AAV8)

    Viral Prep

    #137151-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-NpHR3.3-EYFP (#137151). In addition to the viral particles, you will also receive purified pAAV-nEF-NpHR3.3-EYFP plasmid DNA. nEF-driven expression of NpHR3.3-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP

    Available since

    May 5, 2021

    Availability

    Academic Institutions and Nonprofits only

46. pAAV-GFAP-HA-rM3D(Gs)-IRES-mCitrine (AAV5)

    Viral Prep

    #50472-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-GFAP-HA-rM3D(Gs)-IRES-mCitrine (#50472). In addition to the viral particles, you will also receive purified pAAV-GFAP-HA-rM3D(Gs)-IRES-mCitrine plasmid DNA. GFAP-driven HA-tagged rM3D(Gs) and bicistronic mCitrine expression, for chemogenetic excitation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    GFAP

    Tags

    mCitrine

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

47. pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40 (AAV9)

    Viral Prep

    #98931-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40 (#98931). In addition to the viral particles, you will also receive purified pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40 plasmid DNA. Synapsin-driven, Cre-dependent, iGluSnFr glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    Syn

    Tags

    None

    Available since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

48. pAAV-CaMKIIa-ChRmine-oScarlet-KV 2.1-WPRE (AAV8)

    Viral Prep

    #183519-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-ChRmine-oScarlet-KV 2.1-WPRE (#183519). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-ChRmine-oScarlet-KV 2.1-WPRE plasmid DNA. CaMKIIa-driven expression of ChRmine-oScarlet-KV 2.1. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Kishi et al Cell. 2022 Feb 17;185(4):672-689.e23. do

    Promoter

    CaMKII

    Tags

    None

    Available since

    Dec. 18, 2024

    Availability

    Academic Institutions and Nonprofits only

49. AAV-CamKIIa-jGCaMP8s-WPRE (AAV Retrograde)

    Viral Prep

    #176752-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CamKIIa-jGCaMP8s-WPRE (#176752). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8s-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8s. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CamKIIalpha

    Tags

    None

    Available since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

50. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV8)

    Viral Prep

    #105542-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    CB7

    Tags

    EGFP

    Available since

    July 25, 2018

    Availability

    Academic Institutions and Nonprofits only