1,043 results

1. pGP-AAV-CAG-FLEX-jGCaMP8f-WPRE (AAV5)

   Viral Prep

   #162382-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pGP-AAV-CAG-FLEX-jGCaMP8f-WPRE (#162382). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8f-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of the ultrafast calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Article

   Zhang et al Janelia Research Campus, Online Resource

   Promoter

   CAG

   Tags

   None

   Available Since

   Sept. 27, 2023

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-hSyn-JEDI-2P-Kv-WPRE (AAV9)

   Viral Prep

   #179463-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSyn-JEDI-2P-Kv-WPRE (#179463). In addition to the viral particles, you will also receive purified pAAV-hSyn-JEDI-2P-Kv-WPRE plasmid DNA. hSyn-driven expression (soma and AIS-localized) of the genetically encoded voltage indicator JEDI-2P. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Francois St-Pierre

   Article

   Liu et al Cell. 2022 Aug 16. pii: S0092-8674(22)00

   Promoter

   Syn

   Tags

   None

   Available Since

   Jan. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-CAG-FLEX-EGFP (AAV1)

   Viral Prep

   #59331-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CAG-FLEX-EGFP (#59331). In addition to the viral particles, you will also receive purified pAAV-CAG-FLEX-EGFP plasmid DNA. CAG-driven, Cre-dependent expression of EGFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ian Wickersham

   Promoter

   CAG

   Tags

   EGFP

   Available Since

   July 12, 2023

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-nEF-Con/Fon-ChR2-mCherry (AAV8)

   Viral Prep

   #137142-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-ChR2-mCherry (#137142). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-ChR2-mCherry plasmid DNA. nEF-driven, Cre and Flp-dependent expression of channelrhodopsin fused to mCherry for optogenetic activation.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   mCherry (Cre and Flp-dependent)

   Available Since

   Feb. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

5. pAAV.CAG.FLEX.iGluSnFR3.v857.PDGFR (AAV2)

   Viral Prep

   #196219-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV.CAG.FLEX.iGluSnFR3.v857.PDGFR (#196219). In addition to the viral particles, you will also receive purified pAAV.CAG.FLEX.iGluSnFR3.v857.PDGFR plasmid DNA. CAG-driven, Cre-dependent third generation glutamate sensor iGluSnFR3, variant 857. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Kaspar Podgorski

   Article

   Aggarwal et al Nat Methods. 2023 May 4. doi: 10.1038/s4

   Promoter

   Tags

   None

   Available Since

   Aug. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-Ef1a-Con/Foff 2.0-GCaMP6F (AAV8)

   Viral Prep

   #137123-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-GCaMP6F (#137123). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-GCaMP6F plasmid DNA. EF1a-driven, Cre-dependent expression of GCaMP6f (inhibited in presence of Flp). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   EF1a

   Tags

   None

   Available Since

   May 5, 2021

   Availability

   Academic Institutions and Nonprofits only

7. AAV-EF1a-jGCaMP8s-WPRE (AAV9)

   Viral Prep

   #176758-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from AAV-EF1a-jGCaMP8s-WPRE (#176758). In addition to the viral particles, you will also receive purified AAV-EF1a-jGCaMP8s-WPRE plasmid DNA. EF1a-driven expression of calcium sensor GCaMP8s. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   EF1a

   Tags

   None

   Available Since

   Feb. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

8. AAV-hSyn1-GCaMP6f-P2A-nls-dTomato (AAV Retrograde)

   Viral Prep

   #51085-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from AAV-hSyn1-GCaMP6f-P2A-nls-dTomato (#51085). In addition to the viral particles, you will also receive purified AAV-hSyn1-GCaMP6f-P2A-nls-dTomato plasmid DNA. GCaMP6f calcium sensor and bicistronic, physically separate nuclear localized dTomato expression under a human synapsin1 promoter. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jonathan Ting

   Promoter

   Syn

   Tags

   nuclear dTomato (physically separate, not a fusion protein)

   Available Since

   May 10, 2017

   Availability

   Academic Institutions and Nonprofits only

9. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV9)

   Viral Prep

   #87306-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Li Zhang

   Article

   Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

   Promoter

   EF1a

   Tags

   None

   Available Since

   Jan. 26, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-Ef1a-DIO ChETA-EYFP (AAV1)

    Viral Prep

    #26968-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-Ef1a-DIO ChETA-EYFP (#26968). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO ChETA-EYFP plasmid DNA. EF1a-driven, Cre-dependent, ChETA fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Gunaydin et al Nat Neurosci. 2010 Mar;13(3):387-92. doi

    Promoter

    EF1a

    Tags

    EYFP (Cre-dependent)

    Available Since

    Feb. 21, 2018

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-mDlx-NLS-mRuby2 (AAV PHP.eB)

    Viral Prep

    #99130-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    mDLX5/6

    Tags

    mRuby2

    Available Since

    Feb. 16, 2024

    Availability

    Academic Institutions and Nonprofits only

12. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV8)

    Viral Prep

    #87306-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Li Zhang

    Article

    Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

    Promoter

    EF1a

    Tags

    None

    Available Since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-Ef1a-fDIO hChR2(H134R)-EYFP (AAV Retrograde)

    Viral Prep

    #55639-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-Ef1a-fDIO hChR2(H134R)-EYFP (#55639). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO hChR2(H134R)-EYFP plasmid DNA. Ef1a-driven, Flp-dependent expression of ChR2(H134R)-EYFP. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    EF1a

    Tags

    EYFP

    Available Since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

14. pAAV_hSyn-DIO-PdCO-mScarlet-WPRE (AAV1)

    Viral Prep

    #198511-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV_hSyn-DIO-PdCO-mScarlet-WPRE (#198511). In addition to the viral particles, you will also receive purified pAAV_hSyn-DIO-PdCO-mScarlet-WPRE plasmid DNA. Syn-driven Cre-dependent expression of optimized PdCO in frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

    Promoter

    Syn

    Tags

    mScarlet (Cre-dependent)

    Available Since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

15. CaMKII-somBiPOLES-mCerulean (AAV5)

    Viral Prep

    #154948-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from CaMKII-somBiPOLES-mCerulean (#154948). In addition to the viral particles, you will also receive purified CaMKII-somBiPOLES-mCerulean plasmid DNA. CamKII-driven expression of soma-targeted BiPOLES for optogenetic inhibition (blue light) and activation (red light). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Simon Wiegert

    Article

    Vierock et al Nat Commun. 2021 Jul 26;12(1):4527. doi:

    Promoter

    CaMKIIa(0.4)

    Tags

    mCerulean

    Available Since

    Sept. 1, 2021

    Availability

    Academic Institutions and Nonprofits only

16. pAAV_hSyn1-SIO-stGtACR2-FusionRed (AAV Retrograde)

    Viral Prep

    #105677-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV_hSyn1-SIO-stGtACR2-FusionRed (#105677). In addition to the viral particles, you will also receive purified pAAV_hSyn1-SIO-stGtACR2-FusionRed plasmid DNA. Synapsin-driven, Cre-dependent, soma-targeted anion-conducting channelrhodopsin fused to FusionRed for optogenetic inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Nat Commun. 2018 Oct 8;9(1):4125. doi: 1

    Promoter

    Syn

    Tags

    FusionRed (Cre-dependent)

    Available Since

    July 8, 2020

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-hsyn-GRAB_DA-mut (AAV9)

    Viral Prep

    #140555-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hsyn-GRAB_DA-mut (#140555). In addition to the viral particles, you will also receive purified pAAV-hsyn-GRAB_DA-mut plasmid DNA. Synapsin-driven expression of control dopamine sensor GRAB_DA-mut (does not respond to DA). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Yulong Li

    Article

    Sun et al Nat Methods. 2020 Nov;17(11):1156-1166.

    Promoter

    Syn

    Tags

    None

    Available Since

    Aug. 31, 2021

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA (AAV1)

    Viral Prep

    #68719-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA (#68719). In addition to the viral particles, you will also receive purified pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6f-WPRE-pA plasmid DNA. CAG-driven, Cre-dependent GCaMP6f calcium sensor with bicistronic mRuby2. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Tobias Rose, Mark Huebener, Tobias Bonhoeffer

    Article

    Rose et al Science. 2016 Jun 10;352(6291):1319-22.

    Promoter

    CAG-FLEX

    Tags

    mRuby2 (Cre-dependent)

    Available Since

    June 5, 2018

    Availability

    Academic Institutions and Nonprofits only

19. pENN.AAV.EF1a.eGFP.WPRE.rBG (AAV Retrograde)

    Viral Prep

    #105547-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pENN.AAV.EF1a.eGFP.WPRE.rBG (#105547). In addition to the viral particles, you will also receive purified pENN.AAV.EF1a.eGFP.WPRE.rBG plasmid DNA. EF1a-driven EGFP expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    EF1a

    Tags

    EGFP

    Available Since

    Oct. 18, 2021

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-S5E2-GCaMP6f (AAV1)

    Viral Prep

    #135632-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-S5E2-GCaMP6f (#135632). In addition to the viral particles, you will also receive purified pAAV-S5E2-GCaMP6f plasmid DNA. Expression of GCaMP6f under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    None

    Available Since

    Nov. 11, 2020

    Availability

    Academic Institutions and Nonprofits only