1,043 results

1. pAAV-Ef1a-DIO-Synaptophysin-GCaMP6s (AAV5)

   Viral Prep

   #105715-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-Ef1a-DIO-Synaptophysin-GCaMP6s (#105715). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO-Synaptophysin-GCaMP6s plasmid DNA. EF1a-driven, Cre-dependent GCaMP6s fused to the presynaptic protein synaptophysin. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Rylan Larsen

   Promoter

   Ef1a, Human elongation factor-1 alpha

   Tags

   None

   Available Since

   Oct. 20, 2020

   Availability

   Academic Institutions and Nonprofits only

2. pAAV.hSyn.eGFP.WPRE.bGH (AAV1)

   Viral Prep

   #105539-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSyn.eGFP.WPRE.bGH (#105539). In addition to the viral particles, you will also receive purified pAAV.hSyn.eGFP.WPRE.bGH plasmid DNA. Synapsin-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   Syn

   Tags

   EGFP

   Available Since

   July 23, 2018

   Availability

   Academic Institutions and Nonprofits only

3. pENN.AAV.EF1a.eGFP.WPRE.rBG (AAV5)

   Viral Prep

   #105547-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pENN.AAV.EF1a.eGFP.WPRE.rBG (#105547). In addition to the viral particles, you will also receive purified pENN.AAV.EF1a.eGFP.WPRE.rBG plasmid DNA. EF1a-driven EGFP expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   EF1a

   Tags

   EGFP

   Available Since

   May 4, 2018

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-mDlx-GFP-Fishell-1 (AAV Retrograde)

   Viral Prep

   #83900-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-mDlx-GFP-Fishell-1 (#83900). In addition to the viral particles, you will also receive purified pAAV-mDlx-GFP-Fishell-1 plasmid DNA. mDlx-driven expression of GFP in GABA-ergic interneurons. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Gordon Fishell

   Article

   Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

   Promoter

   mDlx

   Tags

   GFP

   Available Since

   June 1, 2020

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine (AAV8)

   Viral Prep

   #50467-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine (#50467). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine plasmid DNA. CaMKIIa-driven HA-tagged hM4D(Gi) and bicistronic mCitrine expression, for chemogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   CaMKII

   Tags

   mCitrine

   Available Since

   May 29, 2020

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-S5E2-GFP-fGFP (AAV1)

   Viral Prep

   #135631-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-S5E2-GFP-fGFP (#135631). In addition to the viral particles, you will also receive purified pAAV-S5E2-GFP-fGFP plasmid DNA. Bicistronic expression of GFP and membrane-targeted GFP under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jordane Dimidschstein

   Article

   Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

   Promoter

   Tags

   EGFP

   Available Since

   Sept. 15, 2021

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn-hM3D(Gq)-mCherry (AAV1)

   Viral Prep

   #50474-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn-hM3D(Gq)-mCherry (#50474). In addition to the viral particles, you will also receive purified pAAV-hSyn-hM3D(Gq)-mCherry plasmid DNA. hSyn-driven hM3D(Gq) receptor with an mCherry reporter for CNO-induced neuronal activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Promoter

   Syn

   Tags

   mCherry

   Available Since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP (AAV8)

   Viral Prep

   #137153-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP (#137153). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-NpHR3.3-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of NpHR3.3-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre-dependent)

   Available Since

   April 8, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pAAV.hSynap.iAChSnFR (AAV1)

   Viral Prep

   #137950-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSynap.iAChSnFR (#137950). In addition to the viral particles, you will also receive purified pAAV.hSynap.iAChSnFR plasmid DNA. Synapsin-driven, iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Borden et al bioRxiv 2020

   Promoter

   hSynanpsin

   Tags

   None

   Available Since

   Sept. 15, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-Ef1a-fDIO EYFP (AAV Retrograde)

    Viral Prep

    #55641-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-Ef1a-fDIO EYFP (#55641). In addition to the viral particles, you will also receive purified pAAV-Ef1a-fDIO EYFP plasmid DNA. EF1a-driven, Flp-dependent expression of EYFP. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

    Promoter

    EF1a

    Tags

    EYFP (Flp-dependent)

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-EF1a-Flp-DOG-NW (AAV1)

    Viral Prep

    #75469-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-EF1a-Flp-DOG-NW (#75469). In addition to the viral particles, you will also receive purified pAAV-EF1a-Flp-DOG-NW plasmid DNA. EF1a-driven expression of Flp recombinase dependent on GFP (Flp-DOG); to be coinjected with GFP (or for use with transgenic GFP animals). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Connie Cepko

    Article

    Tang et al Elife. 2016 May 20;5. pii: e15312. doi:

    Promoter

    EF-1a

    Tags

    None

    Available Since

    Feb. 19, 2020

    Availability

    Academic Institutions and Nonprofits only

12. pENN.AAV.CAG.Flex.GFPsm_myc.WPRE.SV40 (AAV1)

    Viral Prep

    #98927-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pENN.AAV.CAG.Flex.GFPsm_myc.WPRE.SV40 (#98927). In addition to the viral particles, you will also receive purified pENN.AAV.CAG.Flex.GFPsm_myc.WPRE.SV40 plasmid DNA. CAG-driven, Cre-dependent expression of GFPsm_myc spaghetti monster construct. Spaghetti monster constructs are not fluorescent ("dark") to allow full range of antibody staining. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Viswanathan et al Nat Methods. 2015 Jun;12(6):568-76. doi:

    Promoter

    CAG

    Tags

    GFPsm-myc (spaghetti monster construct)

    Available Since

    June 12, 2018

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-EF1α1.1-GFP (AAV2)

    Viral Prep

    #122100-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-EF1α1.1-GFP (#122100). In addition to the viral particles, you will also receive purified pAAV-EF1α1.1-GFP plasmid DNA. EF1a-driven expression of GFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Edward Boyden

    Article

    Klapoetke et al Nat Methods. 2014 Mar;11(3):338-46. doi:

    Promoter

    EF1a（1.1kb short version)

    Tags

    GFP

    Available Since

    Aug. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP (AAV8)

    Viral Prep

    #137148-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP (#137148). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Fon-Arch3.3-p2a-EYFP plasmid DNA. nEF-driven, Cre and Flp-dependent expression of Arch3.3-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre and Flp-dependent)

    Available Since

    May 6, 2021

    Availability

    Academic Institutions and Nonprofits only

15. AiP12610 - pAAV-AiE0780m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2610) (AAV PHP.eB)

    Viral Prep

    #191737-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP12610 - pAAV-AiE0780m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2610) (#191737). In addition to the viral particles, you will also receive purified AiP12610 - pAAV-AiE0780m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2610) plasmid DNA. minBG-driven expression of SYFP2 in striatal direct pathway medium spiny neurons (D1-MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Promoter

    Tags

    SYFP2

    Available Since

    Nov. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

16. AiP14496: pAAV-AiE0873m_3xC2-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN4496) (AAV PHP.eB)

    Viral Prep

    #214858-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from AiP14496: pAAV-AiE0873m_3xC2-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN4496) (#214858). In addition to the viral particles, you will also receive purified AiP14496: pAAV-AiE0873m_3xC2-minBG-SYFP2-P2A-3XFLAG-10aa-H2B-WPRE3-BGHpA (Alias: CN4496) plasmid DNA. minBG-driven expression of SYFP2 plus a separate nuclear FLAG epitope in striatal cholinergic neurons. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Promoter

    Tags

    SYFP2

    Available Since

    Nov. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-nEF-Con/Foff 2.0-ChR2(ET/TC)-EYFP (AAV8)

    Viral Prep

    #137140-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-ChR2(ET/TC)-EYFP (#137140). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-ChR2(ET/TC)-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of ChR2(E123T/T159C)-EYFP (inhibited in presence of Flp) for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    nEF

    Tags

    EYFP (Cre-dependent)

    Available Since

    May 6, 2021

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 (AAV9)

    Viral Prep

    #124650-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 (#124650). In addition to the viral particles, you will also receive purified pAAV-CamKIIa-C1V1(t/t)-mScarlet-KV2.1 plasmid DNA. CamKIIa-driven expression of C1V1(t/t) fused to mScarlet fluorophore and targeted to neuronal soma for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Christopher Harvey

    Article

    Chettih et al Nature. 2019 Mar 6. pii: 10.1038/s41586-

    Promoter

    CaMKII

    Tags

    mScarlet

    Available Since

    Dec. 2, 2019

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-mDlx-NLS-mRuby2 (AAV1)

    Viral Prep

    #99130-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    mDLX5/6

    Tags

    mRuby2

    Available Since

    Jan. 14, 2019

    Availability

    Academic Institutions and Nonprofits only

20. Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A (Lentiviral Prep)

    Viral Prep

    #92385-LV

    Purpose

    Ready-to-use Lentiviral Prep particles produced from Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A (#92385). In addition to the viral particles, you will also receive purified Human CRISPRi sgRNA library Dolcetto in backbone XPR_050, Set A plasmid DNA.

    Depositor

    David Root, John Doench

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Promoter

    Tags

    None

    Available Since

    Sept. 2, 2020

    Availability

    Academic Institutions and Nonprofits only