966 results

1. pAAV-nEF-Con/Foff 2.0-iC++-EYFP (AAV8)

   Viral Prep

   #137156-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-iC++-EYFP (#137156). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-iC++-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of chloride-conducting channelrhodopsin iC++-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre-dependent)

   Available since

   Nov. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

2. pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (AAV5)

   Viral Prep

   #98930-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (#98930). In addition to the viral particles, you will also receive purified pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 plasmid DNA. GFAP-driven glutamate sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

   Promoter

   GFAP

   Tags

   None

   Available since

   Feb. 27, 2018

   Availability

   Academic Institutions and Nonprofits only

3. AAV-mDlx-jGCaMP8f-WPRE (AAV9)

   Viral Prep

   #176753-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from AAV-mDlx-jGCaMP8f-WPRE (#176753). In addition to the viral particles, you will also receive purified AAV-mDlx-jGCaMP8f-WPRE plasmid DNA. mDlx enhancer-driven expression of calcium sensor GCaMP8f in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   mDlx

   Tags

   None

   Available since

   Feb. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-hSyn-GRAB_NE1h (AAV Retrograde)

   Viral Prep

   #123309-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-GRAB_NE1h (#123309). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_NE1h plasmid DNA. hSyn-driven expression of GRAB-NE1h norepinephrine sensor in neurons. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Yulong Li

   Article

   Feng et al Neuron. 2019 May 22;102(4):745-761.e8. d

   Promoter

   Syn

   Tags

   None

   Available since

   June 22, 2020

   Availability

   Academic Institutions and Nonprofits only

5. AAV-CamKIIa-jGCaMP8f-WPRE (AAV Retrograde)

   Viral Prep

   #176750-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from AAV-CamKIIa-jGCaMP8f-WPRE (#176750). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8f-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8f. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   CamKIIalpha

   Tags

   None

   Available since

   July 21, 2023

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-double floxed-eNpHR-EYFP-WPRE-pA (AAV9)

   Viral Prep

   #20949-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-double floxed-eNpHR-EYFP-WPRE-pA (#20949). In addition to the viral particles, you will also receive purified pAAV-double floxed-eNpHR-EYFP-WPRE-pA plasmid DNA. EF1a-driven, cre-dependent eNpHR EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   EF1a

   Tags

   EYFP (Cre-dependent)

   Available since

   July 12, 2018

   Availability

   Academic Institutions and Nonprofits only

7. pAAV-hSyn-GRAB_OTmut (AAV1)

   Viral Prep

   #185388-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn-GRAB_OTmut (#185388). In addition to the viral particles, you will also receive purified pAAV-hSyn-GRAB_OTmut plasmid DNA. hSyn-driven expression of the genetically-encoded fluorescent oxytocin(OT) control sensor GRAB_OTmut in neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Yulong Li

   Article

   Qian et al Nat Biotechnol. 2023 Jan 2. doi: 10.1038

   Promoter

   Syn

   Tags

   None

   Available since

   Oct. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (AAV1)

   Viral Prep

   #68717-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA (#68717). In addition to the viral particles, you will also receive purified pAAV-CAG-Flex-mRuby2-GSG-P2A-GCaMP6s-WPRE-pA plasmid DNA. CAG-driven, Cre dependent, GCaMP6s calcium sensor and bicistronic, physically separate mRuby2 expression. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Mark Huebener, Tobias Rose, Tobias Bonhoeffer

   Article

   Rose et al Science. 2016 Jun 10;352(6291):1319-22.

   Promoter

   CAG-FLEX

   Tags

   mRuby2 (Cre-dependent)

   Available since

   May 4, 2018

   Availability

   Academic Institutions and Nonprofits only

9. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV9)

   Viral Prep

   #105542-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   CB7

   Tags

   EGFP

   Available since

   Aug. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

10. AAV-CAG-jGCaMP8f-WPRE (AAV1)

    Viral Prep

    #179254-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from AAV-CAG-jGCaMP8f-WPRE (#179254). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8f-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8f. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CAG

    Tags

    None

    Available since

    May 18, 2023

    Availability

    Academic Institutions and Nonprofits only

11. pAAV.hSynap-FLEX.SF-iGluSnFR.A184V (AAV1)

    Viral Prep

    #106181-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-iGluSnFR.A184V (#106181). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-iGluSnFR.A184V plasmid DNA. Synapsin-driven, Cre-dependent expression of glutamate sensor iGluSnFR (medium affinity). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Tags

    None

    Available since

    March 19, 2021

    Availability

    Academic Institutions and Nonprofits only

12. pGP-AAV-syn-iGABASnFR2(no bind)-WPRE (AAV5)

    Viral Prep

    #218876-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pGP-AAV-syn-iGABASnFR2(no bind)-WPRE (#218876). In addition to the viral particles, you will also receive purified pGP-AAV-syn-iGABASnFR2(no bind)-WPRE plasmid DNA. Syn-driven expression of the improved GABA sensor control iGABASnFR2(no bind) (no change in fluorescence). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Kolb et al bioRxiv 2025.03.25.644953

    Promoter

    Syn

    Tags

    None

    Available since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

13. pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (AAV8)

    Viral Prep

    #112677-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP (#112677). In addition to the viral particles, you will also receive purified pOTTC1032 - pAAV EF1a Nuc-flox(mCherry)-EGFP plasmid DNA. EF1a-driven, Cre-dependent color switch. This AAV directs expression of nuclear mCherry in the absence of Cre. In the presence of Cre, nuclear EGFP (and not mCherry) will be expressed. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Brandon Harvey

    Article

    Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

    Promoter

    EF1a

    Tags

    mCherry (Cre-negative cells), EGFP (Cre-positive cells)

    Available since

    Sept. 8, 2020

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-S5E2-C1V1-eYFP (AAV9)

    Viral Prep

    #135633-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-C1V1-eYFP (#135633). In addition to the viral particles, you will also receive purified pAAV-S5E2-C1V1-eYFP plasmid DNA. Expression of red-shifted opsin C1V1 fused to EYFP under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    EYFP

    Available since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pAAV-synapsin-HaloCaMP1a-EGFP (AAV1)

    Viral Prep

    #138327-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-synapsin-HaloCaMP1a-EGFP (#138327). In addition to the viral particles, you will also receive purified pAAV-synapsin-HaloCaMP1a-EGFP plasmid DNA. Synapsin-driven HaloCaMP1a, a far-red calcium sensor, fused to EGFP. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Eric Schreiter

    Article

    Deo et al Nat Chem Biol. 2021 Jun;17(6):718-723. d

    Promoter

    Syn

    Tags

    EGFP

    Available since

    Sept. 15, 2021

    Availability

    Academic Institutions and Nonprofits only

16. AAV pEF1a-DIO-FLPo-WPRE-hGHpA (AAV2)

    Viral Prep

    #87306-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from AAV pEF1a-DIO-FLPo-WPRE-hGHpA (#87306). In addition to the viral particles, you will also receive purified AAV pEF1a-DIO-FLPo-WPRE-hGHpA plasmid DNA. EF1a-driven, Cre dependent expression of the site-specific recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Li Zhang

    Article

    Zingg et al Neuron. 2017 Jan 4;93(1):33-47. doi: 10.

    Promoter

    EF1a

    Tags

    None

    Available since

    Aug. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

17. pAAV-CaMKIIa-hChR2(E123A)-mCherry (AAV9)

    Viral Prep

    #35506-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hChR2(E123A)-mCherry (#35506). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(E123A)-mCherry plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin E123A mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Mattis et al Nat Methods. 2011 Dec 18;9(2):159-72. do

    Promoter

    CaMKII

    Tags

    mCherry

    Available since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

18. AAV-CAG-jGCaMP8m-WPRE (AAV Retrograde)

    Viral Prep

    #179255-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CAG-jGCaMP8m-WPRE (#179255). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8m-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8m. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CAG

    Tags

    None

    Available since

    March 18, 2024

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 (AAV9)

    Viral Prep

    #112007-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 (#112007). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 plasmid DNA. hSyn-driven expression of calcium sensor GCaMP6s and bicistronic mRuby3. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

    Promoter

    Syn

    Tags

    mRuby3

    Available since

    Feb. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

20. pAAV CD68-hM4D(Gi)-mCherry (AAV1)

    Viral Prep

    #75033-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV CD68-hM4D(Gi)-mCherry (#75033). In addition to the viral particles, you will also receive purified pAAV CD68-hM4D(Gi)-mCherry plasmid DNA. CD68-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced microglial inhibition. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Grace et al Proc Natl Acad Sci U S A. 2016 Jun 14;11

    Promoter

    CD68

    Tags

    mCherry

    Available since

    March 27, 2019

    Availability

    Academic Institutions and Nonprofits only