1,043 results

1. pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (AAV9)

   Viral Prep

   #172922-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (#172922). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 plasmid DNA. hSyn-driven expression of jGCaMP8m in axons with cytosolic expression of mRuby3. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Promoter

   Syn

   Tags

   None

   Available Since

   Aug. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

2. pAAV-nEF-Con/Foff 2.0-iC++-EYFP (AAV8)

   Viral Prep

   #137156-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-nEF-Con/Foff 2.0-iC++-EYFP (#137156). In addition to the viral particles, you will also receive purified pAAV-nEF-Con/Foff 2.0-iC++-EYFP plasmid DNA. nEF-driven, Cre-dependent expression of chloride-conducting channelrhodopsin iC++-EYFP (inhibited in presence of Flp) for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   INTRSECT 2.0 Project, Karl Deisseroth

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   nEF

   Tags

   EYFP (Cre-dependent)

   Available Since

   Nov. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 (AAV5)

   Viral Prep

   #108422-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 (#108422). In addition to the viral particles, you will also receive purified pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2 plasmid DNA. CAG-driven, Cre dependent Archon1, an opsin-based fluorescent voltage indicator, fused to EGFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Article

   Piatkevich et al Nat Chem Biol. 2018 Feb 26. pii: 10.1038

   Promoter

   CAG

   Tags

   EGFP (Cre-dependent)

   Available Since

   Sept. 17, 2018

   Availability

   Academic Institutions and Nonprofits only

4. pAAV_hSyn-PdCO-EGFP-WPRE (AAV5)

   Viral Prep

   #198513-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV_hSyn-PdCO-EGFP-WPRE (#198513). In addition to the viral particles, you will also receive purified pAAV_hSyn-PdCO-EGFP-WPRE plasmid DNA. Synapsin-driven expression of the optimized opsin PdCO in frame with EGFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ofer Yizhar

   Article

   Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

   Promoter

   Syn

   Tags

   EGFP

   Available Since

   April 10, 2024

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-mDlx-NLS-mRuby2 (AAV Retrograde)

   Viral Prep

   #99130-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Viviana Gradinaru

   Article

   Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

   Promoter

   mDLX5/6

   Tags

   mRuby2

   Available Since

   Sept. 18, 2019

   Availability

   Academic Institutions and Nonprofits only

6. pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (AAV Retrograde)

   Viral Prep

   #162381-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (#162381). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Article

   Zhang et al Janelia Research Campus, Online Resource

   Promoter

   CAG

   Tags

   None

   Available Since

   Jan. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

7. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV1)

   Viral Prep

   #105542-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   CB7

   Tags

   EGFP

   Available Since

   May 8, 2018

   Availability

   Academic Institutions and Nonprofits only

8. pENN.AAV.CB7.CI.eGFP.WPRE.rBG (AAV9)

   Viral Prep

   #105542-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pENN.AAV.CB7.CI.eGFP.WPRE.rBG (#105542). In addition to the viral particles, you will also receive purified pENN.AAV.CB7.CI.eGFP.WPRE.rBG plasmid DNA. CB7-driven eGFP. These AAV preparations are suitable purity for injection into animals.

   Depositor

   James M. Wilson

   Promoter

   CB7

   Tags

   EGFP

   Available Since

   Aug. 2, 2018

   Availability

   Academic Institutions and Nonprofits only

9. pAAV CD68-hM4D(Gi)-mCherry (AAV1)

   Viral Prep

   #75033-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV CD68-hM4D(Gi)-mCherry (#75033). In addition to the viral particles, you will also receive purified pAAV CD68-hM4D(Gi)-mCherry plasmid DNA. CD68-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced microglial inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Article

   Grace et al Proc Natl Acad Sci U S A. 2016 Jun 14;11

   Promoter

   CD68

   Tags

   mCherry

   Available Since

   March 27, 2019

   Availability

   Academic Institutions and Nonprofits only

10. pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (AAV5)

    Viral Prep

    #162381-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE (#162381). In addition to the viral particles, you will also receive purified pGP-AAV-CAG-FLEX-jGCaMP8m-WPRE plasmid DNA. CAG-driven, Cre-dependent expression of calcium sensor GCaMP8m (faster, more sensitive). These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Zhang et al Janelia Research Campus, Online Resource

    Promoter

    CAG

    Tags

    None

    Available Since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

11. pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (AAV5)

    Viral Prep

    #98930-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (#98930). In addition to the viral particles, you will also receive purified pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 plasmid DNA. GFAP-driven glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    GFAP

    Tags

    None

    Available Since

    Feb. 27, 2018

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-Ef1a-Con/Foff 2.0-oScarlet (AAV8)

    Viral Prep

    #137137-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-oScarlet (#137137). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-oScarlet plasmid DNA. EF1a-driven, Cre-dependent expression of oScarlet (inhibited in presence of Flp). These AAV preparations are suitable purity for injection into animals.

    Depositor

    INTRSECT 2.0 Project, Karl Deisseroth

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    oScarlet (Cre-dependent)

    Available Since

    April 8, 2021

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-S5E2-Gq-P2A-dTomato (AAV PHP.eB)

    Viral Prep

    #135635-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    dTomato (physically separate, not a fusion protein)

    Available Since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

14. AAV-CamKIIa-jGCaMP8s-WPRE (AAV5)

    Viral Prep

    #176752-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from AAV-CamKIIa-jGCaMP8s-WPRE (#176752). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8s-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8s (more sensitive). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CamKIIalpha

    Tags

    None

    Available Since

    Sept. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

15. AAV-CamKIIa-jGCaMP8f-WPRE (AAV Retrograde)

    Viral Prep

    #176750-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from AAV-CamKIIa-jGCaMP8f-WPRE (#176750). In addition to the viral particles, you will also receive purified AAV-CamKIIa-jGCaMP8f-WPRE plasmid DNA. CamKIIa-driven expression of calcium sensor GCaMP8f. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Promoter

    CamKIIalpha

    Tags

    None

    Available Since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-ihSyn1-DIO-tTA (AAV1)

    Viral Prep

    #99121-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-ihSyn1-DIO-tTA (#99121). In addition to the viral particles, you will also receive purified pAAV-ihSyn1-DIO-tTA plasmid DNA. Cre-dependent expression of the tet-off transactivator from an inducible synapsin promoter. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    ihSyn1

    Tags

    None

    Available Since

    April 4, 2019

    Availability

    Academic Institutions and Nonprofits only

17. pGP-AAV-syn-FLEX-Ace2N-4AA-mNeon-ST A122D WPRE (AAV1)

    Viral Prep

    #172908-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pGP-AAV-syn-FLEX-Ace2N-4AA-mNeon-ST A122D WPRE (#172908). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-Ace2N-4AA-mNeon-ST A122D WPRE plasmid DNA. Syn-driven, Cre-dependent Ace2N-4AA-mNeon-ST A122D expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Article

    Abdelfattah et al Neuron. 2023 Mar 28:S0896-6273(23)00205-

    Promoter

    Syn

    Tags

    mNeon (Cre-dependent)

    Available Since

    Feb. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-CAG-dLight1.2 (AAV1)

    Viral Prep

    #111069-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-dLight1.2 (#111069). In addition to the viral particles, you will also receive purified pAAV-CAG-dLight1.2 plasmid DNA. CAG-driven expression of dLight1.2 dopamine sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Patriarchi et al Science. 2018 Jun 29;360(6396). pii: sci

    Promoter

    Tags

    None

    Available Since

    Feb. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

19. pAAV-S5E2-C1V1-eYFP (AAV9)

    Viral Prep

    #135633-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-S5E2-C1V1-eYFP (#135633). In addition to the viral particles, you will also receive purified pAAV-S5E2-C1V1-eYFP plasmid DNA. Expression of red-shifted opsin C1V1 fused to EYFP under the control of the E2 regulatory element. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    EYFP

    Available Since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-hDlx-Flex-dTomato-Fishell_7 (AAV Retrograde)

    Viral Prep

    #83894-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-hDlx-Flex-dTomato-Fishell_7 (#83894). In addition to the viral particles, you will also receive purified pAAV-hDlx-Flex-dTomato-Fishell_7 plasmid DNA. hDlx-driven, Cre-dependent expression of dTomato. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Gordon Fishell

    Article

    Dimidschstein et al Nat Neurosci. 2016 Oct 31. doi: 10.1038/

    Promoter

    hDlx

    Tags

    dTomato (Cre-dependent)

    Available Since

    June 22, 2020

    Availability

    Academic Institutions and Nonprofits only