963 results

1. pAAV-Ef1a-Con/Foff 2.0-BFP (AAV8)

   Viral Prep

   #137130-AAV8

   Purpose

   Ready-to-use AAV8 particles produced from pAAV-Ef1a-Con/Foff 2.0-BFP (#137130). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Con/Foff 2.0-BFP plasmid DNA. EF1a-driven, Cre-dependent expression of BFP (inhibited in the presence of Flp recombinase). These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth, INTRSECT 2.0 Project

   Article

   Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

   Promoter

   EF1a

   Tags

   BFP (Cre-dependent)

   Available since

   March 19, 2021

   Availability

   Academic Institutions and Nonprofits only

2. pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 (AAV2)

   Viral Prep

   #100054-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 (#100054). In addition to the viral particles, you will also receive purified pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 plasmid DNA. CAG-driven, humanized channelrhodopsin H134R mutant fused to mCherry for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Promoter

   CAG

   Tags

   mCherry

   Available since

   Oct. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

3. pOTTC1596 - pAAV SYN1 HA-hM3D(Gq) (AAV2)

   Viral Prep

   #121539-AAV2

   Purpose

   Ready-to-use AAV2 particles produced from pOTTC1596 - pAAV SYN1 HA-hM3D(Gq) (#121539). In addition to the viral particles, you will also receive purified pOTTC1596 - pAAV SYN1 HA-hM3D(Gq) plasmid DNA. Synapsin-driven, HA-tagged hM3D(Gq) for neuronal activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Christopher Richie

   Article

   Galvan et al Eur J Neurosci. 2019 May 7. doi: 10.1111

   Promoter

   Syn

   Tags

   HA

   Available since

   April 3, 2023

   Availability

   Academic Institutions and Nonprofits only

4. pAAV.hSyn-FLEX.iGABASnFR.F102G (AAV1)

   Viral Prep

   #112164-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.hSyn-FLEX.iGABASnFR.F102G (#112164). In addition to the viral particles, you will also receive purified pAAV.hSyn-FLEX.iGABASnFR.F102G plasmid DNA. Synapsin-driven, Cre-dependent iGABASnFR.F102G GABA sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Marvin et al Nat Methods. 2019 Aug;16(8):763-770. doi

   Promoter

   Syn

   Tags

   None

   Available since

   Jan. 3, 2019

   Availability

   Academic Institutions and Nonprofits only

5. AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) (AAV PHP.eB)

   Viral Prep

   #214852-PHPeB

   Purpose

   Ready-to-use AAV PHP.eB particles produced from AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) (#214852). In addition to the viral particles, you will also receive purified AiP14033: pAAV-AiE0779m_3xC2-minBG-CoChR-EGFP-WPRE3-BGHpA (Alias: CN4033) plasmid DNA. minBG-driven expression of CoChR-EGFP in striatal direct pathway medium spiny neurons (D1 MSNs). These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Jonathan Ting, The Allen Institute for Brain Science

   Article

   Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

   Promoter

   Tags

   EGFP

   Available since

   Nov. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

6. AAV-mDlx-jGCaMP8s-WPRE (AAV9)

   Viral Prep

   #176755-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from AAV-mDlx-jGCaMP8s-WPRE (#176755). In addition to the viral particles, you will also receive purified AAV-mDlx-jGCaMP8s-WPRE plasmid DNA. mDlx-driven expression of the calcium sensor jGCaMP8s in GABA-ergic interneurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   mDlx

   Tags

   None

   Available since

   Feb. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

7. AAV-CAG-jGCaMP8m-WPRE (AAV Retrograde)

   Viral Prep

   #179255-AAVrg

   Purpose

   Ready-to-use AAV Retrograde particles produced from AAV-CAG-jGCaMP8m-WPRE (#179255). In addition to the viral particles, you will also receive purified AAV-CAG-jGCaMP8m-WPRE plasmid DNA. CAG-driven expression of calcium sensor GCaMP8m. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Promoter

   CAG

   Tags

   None

   Available since

   March 18, 2024

   Availability

   Academic Institutions and Nonprofits only

8. pAAV.CAG.iAChSnFR (AAV1)

   Viral Prep

   #137955-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV.CAG.iAChSnFR (#137955). In addition to the viral particles, you will also receive purified pAAV.CAG.iAChSnFR plasmid DNA. CAG-driven iAChSnFR acetylcholine sensor. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Loren Looger

   Article

   Borden et al bioRxiv 2020

   Promoter

   CAG

   Tags

   None

   Available since

   Oct. 28, 2021

   Availability

   Academic Institutions and Nonprofits only

9. pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE (AAV5)

   Viral Prep

   #198516-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE (#198516). In addition to the viral particles, you will also receive purified pAAV_EF1a-DIO-PdCO-mScarlet-ER-miniWPRE plasmid DNA. Ef1a-driven, Cre-dependent expression of the optimized opsin PdCO in frame with mScarlet. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Ofer Yizhar

   Article

   Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

   Promoter

   EF-1a

   Tags

   mScarlet

   Available since

   April 10, 2024

   Availability

   Academic Institutions and Nonprofits only

10. pAAV-CAG-eYFP (AAV Retrograde)

    Viral Prep

    #104055-AAVrg

    Purpose

    Ready-to-use AAV Retrograde particles produced from pAAV-CAG-eYFP (#104055). In addition to the viral particles, you will also receive purified pAAV-CAG-eYFP plasmid DNA. CAG-driven eYFP expression control. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

    Promoter

    CAG

    Tags

    EYFP

    Available since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

11. pAAV-CAG-FlpO (AAV1)

    Viral Prep

    #183412-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV-CAG-FlpO (#183412). In addition to the viral particles, you will also receive purified pAAV-CAG-FlpO plasmid DNA. CAG-driven expression of the recombinase FlpO. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Janelia Viral Tools

    Promoter

    CAG

    Tags

    None

    Available since

    March 27, 2024

    Availability

    Academic Institutions and Nonprofits only

12. pAAV-CAG-iSeroSnFR-Nlgn (AAV9)

    Viral Prep

    #128485-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CAG-iSeroSnFR-Nlgn (#128485). In addition to the viral particles, you will also receive purified pAAV-CAG-iSeroSnFR-Nlgn plasmid DNA. CAG-driven expression of a fluorescent reporter for serotonin (localized to dendrites). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Unger et al Cell. 2020 Dec 12. pii: S0092-8674(20)31

    Promoter

    CAG

    Tags

    None

    Available since

    Feb. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 (AAV5)

    Viral Prep

    #112005-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 (#112005). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3 plasmid DNA. Synapsin-driven, axon-targeted GCaMP6s calcium sensor and mRuby3 expression. The mRuby3 will be a separate protein (not a fusion protein). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Lin Tian

    Article

    Broussard et al Nat Neurosci. 2018 Sep;21(9):1272-1280.

    Promoter

    Syn

    Tags

    mRuby3

    Available since

    Dec. 4, 2018

    Availability

    Academic Institutions and Nonprofits only

14. pAAV-S5E2-Gq-P2A-dTomato (AAV PHP.eB)

    Viral Prep

    #135635-PHPeB

    Purpose

    Ready-to-use AAV PHP.eB particles produced from pAAV-S5E2-Gq-P2A-dTomato (#135635). In addition to the viral particles, you will also receive purified pAAV-S5E2-Gq-P2A-dTomato plasmid DNA. Expression of Gq-DREADD and dTomato (physically separate) under the control of the E2 regulatory element. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Jordane Dimidschstein

    Article

    Vormstein-Schneider et al Nat Neurosci. 2020 Dec;23(12):1629-1636.

    Promoter

    Tags

    dTomato (physically separate, not a fusion protein)

    Available since

    Aug. 27, 2021

    Availability

    Academic Institutions and Nonprofits only

15. pAAV.hSynapsin.SF-iGluSnFR.A184S (AAV9)

    Viral Prep

    #106174-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV.hSynapsin.SF-iGluSnFR.A184S (#106174). In addition to the viral particles, you will also receive purified pAAV.hSynapsin.SF-iGluSnFR.A184S plasmid DNA. hSynapsin driven SF-iGluSnFR.A184S glutamate sensor. The A184S mutant has a higher glutamate affinity. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Tags

    None

    Available since

    Feb. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

16. pAAV-Ef1a-Coff/Fon-BFP (AAV8)

    Viral Prep

    #137131-AAV8

    Purpose

    Ready-to-use AAV8 particles produced from pAAV-Ef1a-Coff/Fon-BFP (#137131). In addition to the viral particles, you will also receive purified pAAV-Ef1a-Coff/Fon-BFP plasmid DNA. EF1a-driven, Flp-dependent expression of BFP (inhibited in presence of Cre). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth, INTRSECT 2.0 Project

    Article

    Fenno et al Neuron. 2020 Jun 20. pii: S0896-6273(20)

    Promoter

    EF1a

    Tags

    BFP (Flp-dependent)

    Available since

    April 5, 2021

    Availability

    Academic Institutions and Nonprofits only

17. pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (AAV5)

    Viral Prep

    #98930-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 (#98930). In addition to the viral particles, you will also receive purified pENN.AAV.GFAP.iGluSnFr.WPRE.SV40 plasmid DNA. GFAP-driven glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2013 Feb;10(2):162-70. doi:

    Promoter

    GFAP

    Tags

    None

    Available since

    Feb. 27, 2018

    Availability

    Academic Institutions and Nonprofits only

18. pAAV-mDlx-NLS-mRuby2 (AAV2)

    Viral Prep

    #99130-AAV2

    Purpose

    Ready-to-use AAV2 particles produced from pAAV-mDlx-NLS-mRuby2 (#99130). In addition to the viral particles, you will also receive purified pAAV-mDlx-NLS-mRuby2 plasmid DNA. mDlx-driven NLS-mRuby2 expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Viviana Gradinaru

    Article

    Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

    Promoter

    mDLX5/6

    Tags

    mRuby2

    Available since

    Sept. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

19. pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (AAV1)

    Viral Prep

    #106183-AAV1

    Purpose

    Ready-to-use AAV1 particles produced from pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S (#106183). In addition to the viral particles, you will also receive purified pAAV.hSynap-FLEX.SF-Venus-iGluSnFR.A184S plasmid DNA. Synapsin-driven, Cre-dependent SF-Venus-iGluSnFR.A184S glutamate sensor. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Loren Looger

    Article

    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do

    Promoter

    Syn

    Tags

    Venus (Cre-dependent)

    Available since

    Dec. 26, 2018

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (AAV9)

    Viral Prep

    #172922-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 (#172922). In addition to the viral particles, you will also receive purified pAAV-hSynapsin1-axon-jGCaMP8m-P2A-mRuby3 plasmid DNA. hSyn-driven expression of jGCaMP8m in axons with cytosolic expression of mRuby3. These AAV preparations are suitable purity for injection into animals.

    Depositor

    GENIE Project

    Promoter

    Syn

    Tags

    None

    Available since

    Aug. 24, 2023

    Availability

    Academic Institutions and Nonprofits only